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anti-CADPS antibody :: Rabbit anti-Human CADPS Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS6009530 anti-CADPS antibody
Unit / Price
0.05 mg  /  $630 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CADPS, Polyclonal Antibody

 Also Known As   

CADPS, CT (Calcium-dependent Secretion Activator 1, Calcium-dependent Activator Protein for Secretion 1, CAPS-1, CAPS, CAPS1, KIAA1121)

 Product Synonym Names    Anti -CADPS, CT (Calcium-dependent Secretion Activator 1, Calcium-dependent Activator Protein for Secretion 1, CAPS-1, CAPS, CAPS1, KIAA1121)
 Product Gene Name   

anti-CADPS antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 3; NC_000003.11 (62384021..62861064, complement). Location: 3p14.2
 OMIM    604667
 3D Structure    ModBase 3D Structure for Q9ULU8
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Recognizes human CADPS. Species sequence homology: mouse and rat.
 Purity/Purification    Affinity Purified
Purified by immunoaffinity chromatography.
 Form/Format    Supplied as a liquid in PBS, 0.02% sodium azide.
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 Immunogen    Synthetic peptide corresponding to aa20 near the C-terminus of the human CAPS1.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-CADPS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-CADPS antibody

   CADPS encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. CADPS acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2).
 Product Categories/Family for anti-CADPS antibody    Antibodies; Abs to Binding Proteins
 Applications Tested/Suitable for anti-CADPS antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-CADPS antibody    Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot: 0.5-1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
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NCBI/Uniprot data below describe general gene information for CADPS. It may not necessarily be applicable to this product.
 NCBI GI #    124297171
 NCBI GeneID    8618
 NCBI Accession #    AAI31732.1 [Other Products]
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 UniProt Primary Accession #    Q9ULU8 [Other Products]
 UniProt Secondary Accession #    Q13339; Q6GQQ6; Q8N2Z5; Q8N3M7; Q8NFR0; Q96BC2; A6NF60 [Other Products]
 UniProt Related Accession #    Q9ULU8 [Other Products]
 Molecular Weight    152,786 Da [Similar Products]
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 NCBI Official Full Name    CADPS protein
 NCBI Official Synonym Full Names    Ca++-dependent secretion activator
 NCBI Official Symbol    CADPS [Similar Products]
 NCBI Official Synonym Symbols   
CAPS; CAPS1; CADPS1
[Similar Products]
 NCBI Protein Information    calcium-dependent secretion activator 1; CAPS-1; Ca2+-dependent secretion activator; Ca2+-regulated cytoskeletal protein; Ca2+-dependent activator protein for secretion; calcium-dependent activator protein for secretion 1
 UniProt Protein Name    Calcium-dependent secretion activator 1
 UniProt Synonym Protein Names   
Calcium-dependent activator protein for secretion 1
 Protein Family    Calcium-dependent secretion activator
 UniProt Gene Name    CADPS [Similar Products]
 UniProt Synonym Gene Names    CAPS; CAPS1; KIAA1121; CAPS-1 [Similar Products]
 UniProt Entry Name    CAPS1_HUMAN
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 NCBI Summary for CADPS    This gene encodes a novel neural/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. The protein acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. [provided by RefSeq, Aug 2008]
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 UniProt Comments for CADPS    CADPS: Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates catecholamine loading of DCVs. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles by acting as a PtdIns(4,5)P2-binding protein that acts at prefusion step following ATP-dependent priming and participates in DCVs-membrane fusion. However, it may also participate in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 3p14.2

Cellular Component: cytoplasmic vesicle membrane; synapse; cytosol; cell junction

Molecular Function: protein binding; metal ion binding; protein kinase binding; lipid binding

Biological Process: catecholamine secretion; protein transport; exocytosis; vesicle organization and biogenesis; synaptic vesicle priming
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 Research Articles on CADPS    1. Increased level of CADPS protein, human in Schizophrenic patients
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CADPS antibodyDiseases associated with anti-CADPS antibody
 Reference Product  PubMed Publications
 CAPS2 antibody  >4 publications with CADPS and CAPS2
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with CADPS and Neoplasms
 Brain Diseases Antibodies  >1 publications with CADPS and Brain Diseases
 Nervous System Diseases Antibodies  >1 publications with CADPS and Nervous System Diseases
Organs/Tissues associated with anti-CADPS antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >7 publications with CADPS and Brain
 Nerve Antibodies  >5 publications with CADPS and Nerve
 Embryonic Tissue Antibodies  >3 publications with CADPS and Embryonic Tissue
 Pituitary Gland Antibodies  >2 publications with CADPS and Pituitary Gland
 Testis Antibodies  >1 publications with CADPS and Testis
 Ovary Antibodies  >1 publications with CADPS and Ovary
 Adrenal Gland Antibodies  >1 publications with CADPS and Adrenal Gland
 Lung Antibodies  >1 publications with CADPS and Lung
 Eye Antibodies  >1 publications with CADPS and Eye
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