View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List Rabbit anti-Human, Mouse CBS Polyclonal Antibody Catalog # MBS627106 Unit / Price 0.2 mL / $770 +1 FREE 8GB USB 5x0.2 mL / $3,295 +4 FREE 8GB USB Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name CBS, Polyclonal Antibody Full Product Name CBS, ID (Cystathionine beta-synthase, Serine Sulfhydrase, Beta-thionase) Product Synonym Names Anti -CBS, ID (Cystathionine beta-synthase, Serine Sulfhydrase, Beta-thionase) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human, Mouse Specificity Recognizes human CBS. Species Crossreactivity: mouse. Purity/Purification Affinity PurifiedPurified by immunoaffinity chromatography. Form/Format Supplied as a liquid in PBS, 0.09% sodium azide. Immunogen Synthetic peptide selected from the Center region of human CBS (KLH). Preparation and Storage May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Other Notes Small volumes of anti-CBS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-CBS antibody CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Product Categories/Family for anti-CBS antibody Antibodies; Abs to Enzymes; Synthase Applications Tested/Suitable for anti-CBS antibody ELISA (EL/EIA), Western Blot (WB) Application Notes for anti-CBS antibody Suitable for use in ELISA and Western Blot.Dilution: ELISA: 1:1,000Western Blot: 1:100-1:500 Immunohistochemistry (IHC) of anti-CBS antibody Formalin-fixed and paraffin-embedded human brain tissue reacted with MBS627106, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western Blot (WB) of anti-CBS antibody Western Blot analysis in Raji cell line, rat brain and cerebellum tissue lysates (35ug/lane) using MBS627106 . This demonstrates the CBS antibody detected the CBS protein (arrow). Immunofluorescence (IF) of anti-CBS antibody Confocal immunofluorescent analysis of 293 cell using MBS627106 followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue). Flow Cytometry (FC/FACS) of anti-CBS antibody Flow cytometric analysis of 293 cells(bottom histogram) using MBS627106 compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. TOP NCBI/Uniprot data below describe general gene information for CBS. It may not necessarily be applicable to this product. NCBI GI # 71915446 TOP NCBI Official Full Name CBS Protein Family Cystathionine beta-synthase TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-CBS antibody Reference Product PubMed Publications FLNA antibody >12 publications with CBS and FLNA Pathways associated with anti-CBS antibody Products by Pathway Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram Focal Adhesion Pathway antibodies Focal Adhesion Pathway Diagram MAPK Signaling Pathway antibodies MAPK Signaling Pathway Diagram MAPK Signaling Pathway antibodies MAPK Signaling Pathway Diagram Salmonella Infection Pathway antibodies Salmonella Infection Pathway Diagram Salmonella Infection Pathway antibodies Salmonella Infection Pathway Diagram Organs/Tissues associated with anti-CBS antibody Organ/Tissue Name Pubmed Publications Bone Antibodies >13 publications with CBS and Bone Connective Tissue Antibodies >4 publications with CBS and Connective Tissue Heart Antibodies >3 publications with CBS and Heart Muscle Antibodies >3 publications with CBS and Muscle Brain Antibodies >3 publications with CBS and Brain Vascular Antibodies >2 publications with CBS and Vascular Embryonic Tissue Antibodies >2 publications with CBS and Embryonic Tissue Ear Antibodies >1 publications with CBS and Ear Kidney Antibodies >1 publications with CBS and Kidney Umbilical Cord Antibodies >1 publications with CBS and Umbilical Cord TOP