Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow Antibody rightarrow CCNE2 rightarrow Polyclonal CCNE2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Stromal cell Derived factor 1Alpha (SDF1Alpha ) ELISA Kit
 • ADH1B Antibody
 • Corticosteroid 11-beta-dehydrogenase isozyme 1 (HSD11B1) Recombinant Protein
 • Complement C3a des Arg ELISA Kit
 • rheumatoid factor (RF) antibody (IgG) ELISA Kit
 • Bacillus anthracis Spore Antigen (Anthrax) Antibody
 • Goat Anti-Human lambda (lambda chain specific) Secondary Antibody
 • Prostaglandin E1 (PGE1) ELISA Kit
 • BLeptin Recombinant Protein
 • collagen, type XVII, alpha 1 (COL17A1) ELISA Kit
 • NELFA Antibody
 • Leukotriene B4 (LTB4) ELISA Kit
 • Fibroblast Growth Factor-21 (mFGF 21) Recombinant Protein
 • fusion (involved in t (12;16) in malignant liposarcoma) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

anti-CCNE2 antibody :: Rabbit anti-Human CCNE2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS129815
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CCNE2, Polyclonal Antibody

 Also Known As   

CCNE2

 Product Gene Name   

anti-CCNE2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 OMIM    603775
 3D Structure    ModBase 3D Structure for O96020
Section Bar
 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
Section Bar
Section Bar
 Species    Human
 Immunogen    Recombinant Protein
Section Bar
 Other Notes    Small volumes of anti-CCNE2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Table BarTOPTable Bar
 Product Categories/Family for anti-CCNE2 antibody    Polyclonal
 Applications Tested/Suitable for anti-CCNE2 antibody   

Western Blot (WB), Immunohistochemistry (IHC)

Section Bar
 Western Blot (WB) of anti-CCNE2 antibody    Western blot analysis of extracts of Jurkat cells, using CCNE2 antibody.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
anti-CCNE2 antibody Western Blot (WB) (WB) image
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for CCNE2. It may not necessarily be applicable to this product.
 NCBI GI #    5921733
 NCBI GeneID    9134
 NCBI Accession #    O96020.1 [Other Products]
Section Bar
 UniProt Primary Accession #    O96020 [Other Products]
 UniProt Secondary Accession #    O95439 [Other Products]
 UniProt Related Accession #    O96020 [Other Products]
 Molecular Weight    404
Table BarTOPTable Bar
 NCBI Official Full Name    G1/S-specific cyclin-E2
 NCBI Official Synonym Full Names    cyclin E2
 NCBI Official Symbol    CCNE2 [Similar Products]
 NCBI Official Synonym Symbols   
CYCE2
[Similar Products]
 NCBI Protein Information    G1/S-specific cyclin-E2
 UniProt Protein Name    G1/S-specific cyclin-E2
 Protein Family    G1/S-specific cyclin
 UniProt Gene Name    CCNE2 [Similar Products]
 UniProt Entry Name    CCNE2_HUMAN
Section Bar
 NCBI Summary for CCNE2    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for CCNE2    CCNE2: Essential for the control of the cell cycle at the late G1 and early S phase. Interacts with the CDK2 (in vivo) and CDK3 (in vitro) protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex. Activated by papilloma viral oncoproteins E6 and E7 which bind to and inactivate p53 and Rb, respectively. According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor- derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon. Belongs to the cyclin family. Cyclin E subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; Activator

Chromosomal Location of Human Ortholog: 8q22.1

Cellular Component: nucleoplasm; cytosol

Molecular Function: protein binding; cyclin-dependent protein kinase regulator activity

Biological Process: DNA replication initiation; cell division; regulation of cyclin-dependent protein kinase activity; mitotic cell cycle; cell cycle checkpoint; G1/S transition of mitotic cell cycle
Table BarTOPTable Bar
 Research Articles on CCNE2    1. Data indicate that miR-26a overexpression inhibited pancreatic cancer cell growth by the downregulation of cyclin E2 expression.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with anti-CCNE2 antibodyPathways associated with anti-CCNE2 antibody
 Reference Product  PubMed Publications
 CDK2 antibody  >20 publications with CCNE2 and CDK2
 CDKN1A antibody  >17 publications with CCNE2 and CDKN1A
 CDKN1B antibody  >6 publications with CCNE2 and CDKN1B
 CDK1 antibody  >5 publications with CCNE2 and CDK1
 CDC25A antibody  >3 publications with CCNE2 and CDC25A
 E2F2 antibody  >2 publications with CCNE2 and E2F2
 CDKN1C antibody  >1 publications with CCNE2 and CDKN1C
 Products by Pathway  Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Checkpoints Pathway antibodies  Cell Cycle Checkpoints Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle - G1/S Transition Pathway antibodies  Cell Cycle - G1/S Transition Pathway Diagram
 Cell Cycle - G1/S Transition Pathway antibodies  Cell Cycle - G1/S Transition Pathway Diagram
 Cellular Senescence Pathway antibodies  Cellular Senescence Pathway Diagram
 Cellular Responses To Stress Pathway antibodies  Cellular Responses To Stress Pathway Diagram
Diseases associated with anti-CCNE2 antibodyOrgans/Tissues associated with anti-CCNE2 antibody
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >17 publications with CCNE2 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >7 publications with CCNE2 and Neoplasm Metastasis
 Lung Diseases Antibodies  >6 publications with CCNE2 and Lung Diseases
 Cell Transformation, Neoplastic Antibodies  >6 publications with CCNE2 and Cell Transformation, Neoplastic
 Skin Neoplasms Antibodies  >5 publications with CCNE2 and Skin Neoplasms
 Lung Neoplasms Antibodies  >5 publications with CCNE2 and Lung Neoplasms
 Liver Diseases Antibodies  >4 publications with CCNE2 and Liver Diseases
 Carcinoma, Squamous Cell Antibodies  >4 publications with CCNE2 and Carcinoma, Squamous Cell
 Hyperplasia Antibodies  >4 publications with CCNE2 and Hyperplasia
 Abnormalities, Drug-Induced Antibodies  >3 publications with CCNE2 and Abnormalities, Drug-Induced
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >8 publications with CCNE2 and Liver
 Lung Antibodies  >6 publications with CCNE2 and Lung
 Skin Antibodies  >5 publications with CCNE2 and Skin
 Ovary Antibodies  >5 publications with CCNE2 and Ovary
 Prostate Antibodies  >5 publications with CCNE2 and Prostate
 Muscle Antibodies  >4 publications with CCNE2 and Muscle
 Lymph Node Antibodies  >3 publications with CCNE2 and Lymph Node
 Embryonic Tissue Antibodies  >2 publications with CCNE2 and Embryonic Tissue
 Bone Antibodies  >2 publications with CCNE2 and Bone
 Testis Antibodies  >2 publications with CCNE2 and Testis
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions