NP_001755.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
30,740 Da
NCBI Official Full Name
T-cell surface glycoprotein CD1b
NCBI Official Synonym Full Names
CD1b molecule
NCBI Protein Information
T-cell surface glycoprotein CD1b
UniProt Protein Name
T-cell surface glycoprotein CD1b
UniProt Synonym Protein Names
CD_antigen: CD1b
NCBI Summary for CD1B
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008]
UniProt Comments for CD1B
Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
Research Articles on CD1B
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Disclaimer
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Products associated with anti-CD1B antibody
Pathways associated with anti-CD1B antibody
Diseases associated with anti-CD1B antibody
Organs/Tissues associated with anti-CD1B antibody
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