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anti-CD1C antibody :: Rabbit anti-Human, Mouse CD1C Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7051829
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD1C, Polyclonal Antibody

★Popular Item★
 Also Known As   

CD1C Antibody

 Product Synonym Names    T-cell surface glycoprotein CD1c; CD1c; CD1C
 Product Gene Name   

anti-CD1C antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    M22178
 3D Structure
   ModBase 3D Structure for P29017
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant Human T-cell surface glycoprotein CD1c protein (18-302AA)
 Conjugation    Non-conjugated
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, pH 7.4
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CD1C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CD1C antibody

   Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
 Applications Tested/Suitable for anti-CD1C antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

 Application Notes for anti-CD1C antibody    WB: 1:500-1:5000
IF: 1:50-1:200
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 Western Blot (WB) of anti-CD1C antibody    Western Blot
Positive WB detected in: Mouse heart tissue
All lanes: CD1C antibody at 3ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 38 KDa
Observed band size: 38 KDa

anti-CD1C antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-CD1C antibody    Immunofluorescent analysis of A549 cells using MBS7051829 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-CD1C antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for CD1C. It may not necessarily be applicable to this product.
 NCBI GI #    110618227
 NCBI GeneID    911
 NCBI Accession #    NP_001756.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001765.2 [Other Products]
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 UniProt Primary Accession #    P29017 [Other Products]
 UniProt Secondary Accession #    Q5TDJ7; Q6IAS4; Q9UMM0; Q9UN96 [Other Products]
 UniProt Related Accession #    P29017 [Other Products]
 Molecular Weight    37,654 Da
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 NCBI Official Full Name    T-cell surface glycoprotein CD1c
 NCBI Official Synonym Full Names    CD1c molecule
 NCBI Official Symbol    CD1C [Similar Products]
 NCBI Official Synonym Symbols   
R7; CD1; CD1A; BDCA1
[Similar Products]
 NCBI Protein Information    T-cell surface glycoprotein CD1c
 UniProt Protein Name    T-cell surface glycoprotein CD1c
 UniProt Synonym Protein Names   
CD_antigen: CD1c
 Protein Family    T-cell surface glycoprotein
 UniProt Gene Name    CD1C [Similar Products]
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 NCBI Summary for CD1C    This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD1C    CD1C: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q23.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: beta-2-microglobulin binding; endogenous lipid antigen binding; exogenous lipid antigen binding; glycolipid binding

Biological Process: antigen processing and presentation, exogenous lipid antigen via MHC class Ib; regulation of immune response; T cell activation during immune response
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 Research Articles on CD1C    1. human CD1c adopts different conformations dependent on ligand occupancy of its groove, with CE and ASG stabilizing CD1c conformations that provide a footprint for binding of CD1c self-reactive T-cell receptors
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD1C antibodyPathways associated with anti-CD1C antibody
 Reference Product  PubMed Publications
 CD4 antibody  >103 publications with CD1C and CD4
 CD40 antibody  >42 publications with CD1C and CD40
 CD86 antibody  >42 publications with CD1C and CD86
 CD83 antibody  >39 publications with CD1C and CD83
 CD19 antibody  >23 publications with CD1C and CD19
 CLEC4C antibody  >17 publications with CD1C and CLEC4C
 CD209 antibody  >6 publications with CD1C and CD209
 Products by Pathway  Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
Diseases associated with anti-CD1C antibodyOrgans/Tissues associated with anti-CD1C antibody
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >43 publications with CD1C and Necrosis
 Skin Diseases Antibodies  >42 publications with CD1C and Skin Diseases
 Nervous System Diseases Antibodies  >18 publications with CD1C and Nervous System Diseases
 Liver Diseases Antibodies  >9 publications with CD1C and Liver Diseases
 Kidney Diseases Antibodies  >9 publications with CD1C and Kidney Diseases
 Anemia Antibodies  >5 publications with CD1C and Anemia
 Hepatitis C Antibodies  >5 publications with CD1C and Hepatitis C
 Muscular Diseases Antibodies  >3 publications with CD1C and Muscular Diseases
 Fetal Diseases Antibodies  >3 publications with CD1C and Fetal Diseases
 Pre-Eclampsia Antibodies  >3 publications with CD1C and Pre-Eclampsia
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >356 publications with CD1C and Blood
 Bone Antibodies  >35 publications with CD1C and Bone
 Lymph Node Antibodies  >33 publications with CD1C and Lymph Node
 Bone Marrow Antibodies  >30 publications with CD1C and Bone Marrow
 Lung Antibodies  >25 publications with CD1C and Lung
 Thymus Antibodies  >21 publications with CD1C and Thymus
 Spleen Antibodies  >20 publications with CD1C and Spleen
 Liver Antibodies  >19 publications with CD1C and Liver
 Intestine Antibodies  >16 publications with CD1C and Intestine
 Vascular Antibodies  >15 publications with CD1C and Vascular
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