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anti-CD27 antibody :: Rabbit CD27 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS551257 anti-CD27 antibody
Unit / Price
0.05 mg  /  $260 +1 FREE 8GB USB
0.2 mg  /  $610 +1 FREE 8GB USB
1 mg  /  $2,145 +2 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD27, Polyclonal Antibody

 Also Known As   

Human CD27 Affinity Purified Polyclonal

 Product Synonym Names    RAA25055; polyclonal; CD27
 Product Gene Name   

anti-CD27 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 12; NC_000012.11 (6554051..6560884). Location: 12p13
 OMIM    186711
 3D Structure    ModBase 3D Structure for P26842
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 Clonality    Polyclonal
 Isotype    Rabbit IgG
 Host    Rabbit
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 Preparation and Storage    This antibody can be stored in working aliquots at 2C - 8C for one month without detectable loss of activity. The antibody is stable for at least 1 year from date of receipt at -20C.


Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-CD27 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CD27 antibody    Antigen affinity polyclonals
 Application Notes for anti-CD27 antibody    Western Blot Concentration: 0.1-0.2 ug/ml
Western Blot Limit: 0.5 ng/lane
ELISA Concentration: 0.1-0.2 ug/ml
ELISA Limit: 2 pg/well
IHC Concentration: 0.1-2 ug/mL
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NCBI/Uniprot data below describe general gene information for CD27. It may not necessarily be applicable to this product.
 NCBI GI #    4507587
 NCBI GeneID    939
 NCBI Accession #    NP_001233.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001242.4 [Other Products]
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 UniProt Primary Accession #    P26842 [Other Products]
 UniProt Secondary Accession #    B2RDZ0 [Other Products]
 UniProt Related Accession #    P26842 [Other Products]
 Molecular Weight    29,137 Da
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 NCBI Official Full Name    CD27 antigen
 NCBI Official Synonym Full Names    CD27 molecule
 NCBI Official Symbol    CD27 [Similar Products]
 NCBI Official Synonym Symbols   
T14; S152; Tp55; TNFRSF7; S152. LPFS2
[Similar Products]
 NCBI Protein Information    CD27 antigen; CD27L receptor; T cell activation antigen S152; T-cell activation antigen CD27; tumor necrosis factor receptor superfamily, member 7
 UniProt Protein Name    CD27 antigen
 UniProt Synonym Protein Names   
CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7
 Protein Family    CD27 antigen
 UniProt Gene Name    CD27 [Similar Products]
 UniProt Synonym Gene Names    TNFRSF7 [Similar Products]
 UniProt Entry Name    CD27_HUMAN
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 NCBI Summary for CD27    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CD27    CD27: Receptor for CD70/CD27L. May play a role in survival of activated T-cells. May play a role in apoptosis through association with SIVA1.

Protein type: Membrane protein, integral; Apoptosis; Receptor, cytokine

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: integral to plasma membrane; extracellular region; external side of plasma membrane

Molecular Function: protein binding; transmembrane receptor activity; caspase inhibitor activity

Biological Process: release of cytoplasmic sequestered NF-kappaB; response to ethanol; cell surface receptor linked signal transduction; positive regulation of JNK cascade; positive regulation of B cell differentiation; negative regulation of caspase activity; immunoglobulin mediated immune response; negative regulation of apoptosis

Disease: Lymphoproliferative Syndrome 2
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 Research Articles on CD27    1. We identified soluble CD27 as an immune modulator associated with enhanced human T cell activation
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD27 antibodyPathways associated with anti-CD27 antibody
 Reference Product  PubMed Publications
 CD70 antibody  >243 publications with CD27 and CD70
 CD38 antibody  >205 publications with CD27 and CD38
 CCR7 antibody  >190 publications with CD27 and CCR7
 CD5 antibody  >101 publications with CD27 and CD5
 CXCR3 antibody  >41 publications with CD27 and CXCR3
 TRAF2 antibody  >13 publications with CD27 and TRAF2
 SIVA1 antibody  >12 publications with CD27 and SIVA1
 TRAF3 antibody  >8 publications with CD27 and TRAF3
 CCR3 antibody  >4 publications with CD27 and CCR3
 CD40LG antibody  >1 publications with CD27 and CD40LG
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
Diseases associated with anti-CD27 antibodyOrgans/Tissues associated with anti-CD27 antibody
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >815 publications with CD27 and Immune System Diseases
 Neoplasms Antibodies  >463 publications with CD27 and Neoplasms
 Necrosis Antibodies  >404 publications with CD27 and Necrosis
 Lymphoma Antibodies  >213 publications with CD27 and Lymphoma
 Inflammation Antibodies  >134 publications with CD27 and Inflammation
 Nervous System Diseases Antibodies  >92 publications with CD27 and Nervous System Diseases
 Skin Diseases Antibodies  >87 publications with CD27 and Skin Diseases
 Neoplasms, Experimental Antibodies  >74 publications with CD27 and Neoplasms, Experimental
 Liver Diseases Antibodies  >56 publications with CD27 and Liver Diseases
 Carcinoma Antibodies  >54 publications with CD27 and Carcinoma
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2100 publications with CD27 and Blood
 Lymph Node Antibodies  >164 publications with CD27 and Lymph Node
 Spleen Antibodies  >136 publications with CD27 and Spleen
 Lymph Antibodies  >134 publications with CD27 and Lymph
 Lung Antibodies  >78 publications with CD27 and Lung
 Thymus Antibodies  >76 publications with CD27 and Thymus
 Kidney Antibodies  >65 publications with CD27 and Kidney
 Tonsil Antibodies  >56 publications with CD27 and Tonsil
 Heart Antibodies  >33 publications with CD27 and Heart
 Intestine Antibodies  >32 publications with CD27 and Intestine
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