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anti-PECAM1 antibody :: Rabbit CD31 (pY713) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS821613 (SPECIAL PRICING: 1 unit is in stock at 40% OFF web price.
Please contact customer service for more information)
Western Blot (WB)
Unit / Price
0.03 mL  /  $165 +1 FREE 8GB USB
0.1 mL  /  $245 +1 FREE 8GB USB
0.2 mL  /  $350 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD31 (pY713) (PECAM1), Polyclonal Antibody

 Also Known As   

Anti-CD31 (pY713) Antibody

 Product Synonym Names    Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD31
 Product Gene Name   

anti-PECAM1 antibody

[Similar Products]
 Antibody/Peptide Pairs    CD31 (pY713) peptide (MBS824008) is used for blocking the activity of CD31 (pY713) antibody (MBS821613)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    173445
 3D Structure    ModBase 3D Structure for P16284
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    Recognizes endogenous levels of CD31 (pY713) protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD31. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-PECAM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-PECAM1 antibody

   Rabbit polyclonal antibody to CD31 (pY713)
 Applications Tested/Suitable for anti-PECAM1 antibody   

Western Blot (WB)

 Application Notes for anti-PECAM1 antibody    WB (1/500 - 1/1000)
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 Western Blot (WB) of anti-PECAM1 antibody    Western blot analysis of CD31 (pY713) expression in HeLa (A), Jurkat (B), K562 (C), NIH3T3 (D), PC12 (E) whole cell lysates.
anti-PECAM1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for PECAM1. It may not necessarily be applicable to this product.
 NCBI GI #    313760624
 NCBI GeneID    5175
 NCBI Accession #    NP_000433.4 [Other Products]
 NCBI GenBank Nucleotide #    NM_000442.4 [Other Products]
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 UniProt Primary Accession #    P16284 [Other Products]
 UniProt Secondary Accession #    Q6LDA9; Q8TBH1; Q96RF5; Q96RF6; Q9NP65; Q9NPB7; Q9NPG9; Q9NQS9; Q9NQT0; A8K3S7; D3DU31 [Other Products]
 UniProt Related Accession #    P16284 [Other Products]
 Molecular Weight    81,378 Da
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 NCBI Official Full Name    platelet endothelial cell adhesion molecule
 NCBI Official Synonym Full Names    platelet/endothelial cell adhesion molecule 1
 NCBI Official Symbol    PECAM1 [Similar Products]
 NCBI Official Synonym Symbols   
CD31; PECA1; GPIIA'; PECAM-1; endoCAM; CD31/EndoCAM
[Similar Products]
 NCBI Protein Information    platelet endothelial cell adhesion molecule; CD31 antigen
 UniProt Protein Name    Platelet endothelial cell adhesion molecule
 UniProt Synonym Protein Names   
EndoCAM; GPIIA'; PECA1; CD_antigen: CD31
 Protein Family    Platelet endothelial cell adhesion molecule
 UniProt Gene Name    PECAM1 [Similar Products]
 UniProt Synonym Gene Names    PECAM-1 [Similar Products]
 UniProt Entry Name    PECA1_HUMAN
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 NCBI Summary for PECAM1    The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]
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 UniProt Comments for PECAM1    PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 17q23.3

Cellular Component: extracellular space; platelet alpha granule membrane; plasma membrane; integral to membrane; cell junction

Molecular Function: protein binding

Biological Process: platelet activation; extracellular matrix organization and biogenesis; platelet degranulation; diapedesis; cell recognition; cell adhesion; signal transduction; blood coagulation; leukocyte migration; phagocytosis
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 Research Articles on PECAM1    1. S. pneumoniae physically binds to PECAM-1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-PECAM1 antibodyDiseases associated with anti-PECAM1 antibody
 Products by Pathway  Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Integrin Cell Surface Interactions Pathway antibodies  Integrin Cell Surface Interactions Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Leukocyte Transendothelial Migration Pathway antibodies  Leukocyte Transendothelial Migration Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Malaria Pathway antibodies  Malaria Pathway Diagram
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >624 publications with PECAM1 and Cardiovascular Diseases
 Inflammation Antibodies  >495 publications with PECAM1 and Inflammation
 Necrosis Antibodies  >401 publications with PECAM1 and Necrosis
 Neoplasms, Experimental Antibodies  >261 publications with PECAM1 and Neoplasms, Experimental
 Lung Diseases Antibodies  >239 publications with PECAM1 and Lung Diseases
 Heart Diseases Antibodies  >229 publications with PECAM1 and Heart Diseases
 Breast Neoplasms Antibodies  >207 publications with PECAM1 and Breast Neoplasms
 Lung Neoplasms Antibodies  >186 publications with PECAM1 and Lung Neoplasms
 Liver Diseases Antibodies  >172 publications with PECAM1 and Liver Diseases
 Atherosclerosis Antibodies  >144 publications with PECAM1 and Atherosclerosis
Organs/Tissues associated with anti-PECAM1 antibody
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >3391 publications with PECAM1 and Vascular
 Blood Antibodies  >2990 publications with PECAM1 and Blood
 Muscle Antibodies  >682 publications with PECAM1 and Muscle
 Embryonic Tissue Antibodies  >509 publications with PECAM1 and Embryonic Tissue
 Lung Antibodies  >428 publications with PECAM1 and Lung
 Heart Antibodies  >347 publications with PECAM1 and Heart
 Skin Antibodies  >337 publications with PECAM1 and Skin
 Brain Antibodies  >322 publications with PECAM1 and Brain
 Connective Tissue Antibodies  >243 publications with PECAM1 and Connective Tissue
 Kidney Antibodies  >234 publications with PECAM1 and Kidney
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