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anti-CD34 antibody :: Rabbit anti-Human CD34 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8216965
Western Blot (WB)
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD34, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-CD34 Antibody

 Product Synonym Names    Hematopoietic progenitor cell antigen CD34; CD34
 Product Gene Name   

anti-CD34 antibody

[Similar Products]
 Antibody/Peptide Pairs    CD34 peptide (MBS8223410) is used for blocking the activity of CD34 antibody (MBS8216965)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    142230
 3D Structure    ModBase 3D Structure for P28906
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Recognizes endogenous levels of CD34 protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD34. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-CD34 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CD34 antibody

   Rabbit polyclonal antibody to CD34
 Applications Tested/Suitable for anti-CD34 antibody   

Western Blot (WB)

 Application Notes for anti-CD34 antibody    WB (1/500 - 1/1000)
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 Western Blot (WB) of anti-CD34 antibody    Western blot analysis of CD34 expression in HeLa (A), HepG2 (B) whole cell lysates.
anti-CD34 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CD34. It may not necessarily be applicable to this product.
 NCBI GI #    68342038
 NCBI GeneID    947
 NCBI Accession #    NP_001020280.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001025109.1 [Other Products]
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 UniProt Primary Accession #    P28906 [Other Products]
 UniProt Secondary Accession #    Q15970; Q15971; Q5JTA3; Q5JTA4; Q9UJB1; A8K664 [Other Products]
 UniProt Related Accession #    P28906 [Other Products]
 Molecular Weight    35,011 Da
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 NCBI Official Full Name    hematopoietic progenitor cell antigen CD34 isoform a
 NCBI Official Synonym Full Names    CD34 molecule
 NCBI Official Symbol    CD34 [Similar Products]
 NCBI Protein Information    hematopoietic progenitor cell antigen CD34
 UniProt Protein Name    Hematopoietic progenitor cell antigen CD34
 UniProt Synonym Protein Names   
CD_antigen: CD34
 Protein Family    Hematopoietic progenitor cell antigen
 UniProt Gene Name    CD34 [Similar Products]
 UniProt Entry Name    CD34_HUMAN
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 NCBI Summary for CD34    The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
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 UniProt Comments for CD34    CD34: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. Belongs to the CD34 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Cell surface

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: intercellular bridge; perinuclear region of cytoplasm; lysosome; integral to plasma membrane; cytoplasm; apical plasma membrane; basal plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: sulfate binding; carbohydrate binding; transcription factor binding

Biological Process: positive regulation of odontogenesis; regulation of immune response; negative regulation of nitric oxide biosynthetic process; glomerular filtration; cell motility involved in cell locomotion; negative regulation of blood coagulation; negative regulation of tumor necrosis factor production; signal transduction; positive regulation of interleukin-10 production; cell proliferation; cell-cell adhesion; positive regulation of angiogenesis; endothelial cell proliferation; regulation of blood pressure; tissue homeostasis; hemopoiesis; leukocyte migration
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 Research Articles on CD34    1. CD34 and CD49b are cell surface markers that can be used to enrich a subpopulation of leiomyoma cells possessing stem/progenitor cell properties.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD34 antibodyPathways associated with anti-CD34 antibody
 Reference Product  PubMed Publications
 KIT antibody  >2076 publications with CD34 and KIT
 CD33 antibody  >1077 publications with CD34 and CD33
 CD19 antibody  >995 publications with CD34 and CD19
 VEGFA antibody  >262 publications with CD34 and VEGFA
 PTPRC antibody  >88 publications with CD34 and PTPRC
 MYB antibody  >62 publications with CD34 and MYB
 CRKL antibody  >31 publications with CD34 and CRKL
 SELL antibody  >4 publications with CD34 and SELL
 DNTT antibody  >2 publications with CD34 and DNTT
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 C-MYB Transcription Factor Network Pathway antibodies  C-MYB Transcription Factor Network Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Cell Adhesion Molecules (CAMs) Pathway antibodies  Cell Adhesion Molecules (CAMs) Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
Diseases associated with anti-CD34 antibodyOrgans/Tissues associated with anti-CD34 antibody
 Disease Name  Pubmed Publications
 Bone Marrow Diseases Antibodies  >2804 publications with CD34 and Bone Marrow Diseases
 Skin Diseases Antibodies  >1845 publications with CD34 and Skin Diseases
 Necrosis Antibodies  >1187 publications with CD34 and Necrosis
 Adenocarcinoma Antibodies  >956 publications with CD34 and Adenocarcinoma
 Anemia Antibodies  >871 publications with CD34 and Anemia
 Breast Neoplasms Antibodies  >860 publications with CD34 and Breast Neoplasms
 Disease Models, Animal Antibodies  >740 publications with CD34 and Disease Models, Animal
 Inflammation Antibodies  >735 publications with CD34 and Inflammation
 Lung Diseases Antibodies  >714 publications with CD34 and Lung Diseases
 Liver Neoplasms Antibodies  >637 publications with CD34 and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >16945 publications with CD34 and Blood
 Bone Antibodies  >10165 publications with CD34 and Bone
 Bone Marrow Antibodies  >9545 publications with CD34 and Bone Marrow
 Vascular Antibodies  >5514 publications with CD34 and Vascular
 Muscle Antibodies  >2560 publications with CD34 and Muscle
 Umbilical Cord Antibodies  >1749 publications with CD34 and Umbilical Cord
 Liver Antibodies  >1672 publications with CD34 and Liver
 Skin Antibodies  >1531 publications with CD34 and Skin
 Lung Antibodies  >1124 publications with CD34 and Lung
 Heart Antibodies  >1060 publications with CD34 and Heart
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