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anti-CD55 antibody :: anti-Human, Mouse CD55 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS178344
Unit / Price
0.1 mg  /  $280 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CD55, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-CD55 Antibody

 Product Synonym Names    Complement decay-accelerating factor; CD 55; CD55; CD55 antigen; CD55 Cromer blood group system; CD55 molecule; CD55 molecule, decay accelerating factor for complement (Cromer blood group); Cd55a; Complement decay accelerating factor; Complement decay-accelerating factor; Complement decay-accelerating factor, GPI-anchored; CR; CROM; Cromer Blood Group antigen; Cromer blood group system; DAF; Daf-GPI; DAF_HUMAN; Daf1; Dcay accelerating factor for complement (CD55, Cromer blood group system); Decay accelarating factor 1, isoform CRA_a; Decay accelerating factor (GPI-form); Decay Accelerating Factor for Complement; Decay accelerating factor GPI-form; Decay accelerating factor soluble-form; GPI-DAF; TC; CD55 molecule, decay accelerating factor for complement (Cromer blood group)
 Product Gene Name   

anti-CD55 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    125240
 3D Structure    ModBase 3D Structure for P08174
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 Clonality    Polyclonal
 Species Reactivity    Human, Mouse
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 Specificity    No cross reactivity with other proteins.
 Purity/Purification    Immunogen Affinity Purified
 Form/Format    Lyophilized
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 Immunogen    E Coli-derived human CD55 recombinant protein (Position: D35-K347). Human CD55 shares 49.1% amino acid (aa) sequence identity with mouse CD55.
 Ig Type    Rabbit IgG
 Reconstitution    Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
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 Preparation and Storage    At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CD55 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CD55 antibody

   Description: Rabbit IgG polyclonal antibody for Complement decay-accelerating factor(CD55) detection. Tested with WB, IHC-P in Human;Mouse.

Background: Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene. This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins.
 Applications Tested/Suitable for anti-CD55 antibody   

Western Blot (WB), Immunohistochemistry (IHC) Paraffin

 Application Notes for anti-CD55 antibody    Western Blot
Concentration: 0.1-0.5ug/ml
Tested Species: Hu, Ms

Immunohistochemistry (IHC) Paraffin:
Concentration: 0.5-1ug/ml
Tested Species: Hu
Antigen Retrieval: By Heat

Tested Species: In-house tested species with positive results.
By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Other applications have not been tested.
Optimal dilutions should be determined by end users.
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 Western Blot (WB) of anti-CD55 antibody    Anti- CD55 Picoband antibody, MBS178344, Western blotting
All lanes: Anti CD55 (MBS178344) at 0.5ug/ml
WB: K562 Whole Cell Lysate at 40ug
Predicted bind size: 41KD
Observed bind size: 41KD
anti-CD55 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CD55 antibody    Anti- CD55 Picoband antibody, MBS178344, IHC(P)
IHC(P): Human Placenta Tissue
anti-CD55 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CD55. It may not necessarily be applicable to this product.
 NCBI GI #    10835143
 NCBI GeneID    1604
 NCBI Accession #    NP_000565.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000574.4 [Other Products]
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 UniProt Primary Accession #    P08174 [Other Products]
 UniProt Secondary Accession #    P09679; P78361; Q14UF2; Q14UF3; Q14UF4; Q14UF5; Q14UF6; B1AP14; D3DT83; D3DT84; E7ER69 [Other Products]
 UniProt Related Accession #    P08174 [Other Products]
 Molecular Weight    59,038 Da
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 NCBI Official Full Name    complement decay-accelerating factor isoform 1 preproprotein
 NCBI Official Synonym Full Names    CD55 molecule (Cromer blood group)
 NCBI Official Symbol    CD55 [Similar Products]
 NCBI Official Synonym Symbols   
CR; TC; DAF; CROM
[Similar Products]
 NCBI Protein Information    complement decay-accelerating factor
 UniProt Protein Name    Complement decay-accelerating factor
 UniProt Synonym Protein Names   
CD_antigen: CD55
 Protein Family    Complement decay-accelerating factor
 UniProt Gene Name    CD55 [Similar Products]
 UniProt Synonym Gene Names    CR; DAF [Similar Products]
 UniProt Entry Name    DAF_HUMAN
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 NCBI Summary for CD55    This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. [provided by RefSeq, Jul 2014]
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 UniProt Comments for CD55    This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
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Product References and Citations for anti-CD55 antibody

   1. Medof ME, Lublin DM, Holers VM, Ayers DJ, Getty RR, Leykam JF, Atkinson JP, Tykocinski ML (April 1987). "Cloning and characterization of cDNAs encoding the complete sequence of decay-accelerating factor of human complement". Proc. Natl. Acad. Sci. U.S.A. 84 (7): 2007-11.
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 Research Articles on CD55    1. present study suggested that the expressions of CD97 antigen and decay accelerating factor DAF were both upregulated in human cervical squamous cell carcinoma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CD55 antibodyPathways associated with anti-CD55 antibody
 Reference Product  PubMed Publications
 CD59 antibody  >883 publications with CD55 and CD59
 CD97 antibody  >52 publications with CD55 and CD97
 EMR2 antibody  >10 publications with CD55 and EMR2
 LCK antibody  >8 publications with CD55 and LCK
 Products by Pathway  Pathway Diagram
 Asparagine N-linked Glycosylation Pathway antibodies  Asparagine N-linked Glycosylation Pathway Diagram
 COPI-mediated Anterograde Transport Pathway antibodies  COPI-mediated Anterograde Transport Pathway Diagram
 Class B/2 (Secretin Family Receptors) Pathway antibodies  Class B/2 (Secretin Family Receptors) Pathway Diagram
 Complement Activation, Classical Pathway antibodies  Complement Activation, Classical Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement And Coagulation Cascades Pathway antibodies  Complement And Coagulation Cascades Pathway Diagram
 Complement Cascade Pathway antibodies  Complement Cascade Pathway Diagram
 ER To Golgi Anterograde Transport Pathway antibodies  ER To Golgi Anterograde Transport Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Hematopoietic Cell Lineage Pathway antibodies  Hematopoietic Cell Lineage Pathway Diagram
Diseases associated with anti-CD55 antibodyOrgans/Tissues associated with anti-CD55 antibody
 Disease Name  Pubmed Publications
 Anemia Antibodies  >352 publications with CD55 and Anemia
 Inflammation Antibodies  >151 publications with CD55 and Inflammation
 Necrosis Antibodies  >86 publications with CD55 and Necrosis
 Disease Models, Animal Antibodies  >73 publications with CD55 and Disease Models, Animal
 Kidney Diseases Antibodies  >62 publications with CD55 and Kidney Diseases
 Nervous System Diseases Antibodies  >59 publications with CD55 and Nervous System Diseases
 Lung Diseases Antibodies  >33 publications with CD55 and Lung Diseases
 Breast Neoplasms Antibodies  >25 publications with CD55 and Breast Neoplasms
 Heart Diseases Antibodies  >24 publications with CD55 and Heart Diseases
 Brain Diseases Antibodies  >23 publications with CD55 and Brain Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >942 publications with CD55 and Blood
 Vascular Antibodies  >213 publications with CD55 and Vascular
 Kidney Antibodies  >157 publications with CD55 and Kidney
 Bone Antibodies  >135 publications with CD55 and Bone
 Heart Antibodies  >132 publications with CD55 and Heart
 Bone Marrow Antibodies  >124 publications with CD55 and Bone Marrow
 Muscle Antibodies  >92 publications with CD55 and Muscle
 Lung Antibodies  >88 publications with CD55 and Lung
 Liver Antibodies  >84 publications with CD55 and Liver
 Ovary Antibodies  >51 publications with CD55 and Ovary
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