View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-CD80 antibody :: Rabbit anti-Human CD80 molecule Polyclonal Antibody Catalog # MBS719249 Unit / Price 0.1 mL / $495 +1 FREE 8GB USB 5x0.1 mL / $2,225 +2 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name CD80 molecule, Polyclonal Antibody Full Product Name Rabbit anti-human CD80 molecule polyclonal Antibody Product Synonym Names CD80 molecule; CD80; CD28LG; CD28LG1; LAB7 Product Gene Name anti-CD80 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 112203 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human Purity/Purification Antigen Affinity Purified Immunogen Human B7-1 Storage Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20 degree C, Avoid freeze / thaw cycles. Santa Cruz Alternative Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1634 / sc-1633 / sc-9091 ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of anti-CD80 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Applications Tested/Suitable for anti-CD80 antibody ELISA (EIA), Western Blot (WB) TOP NCBI/Uniprot data below describe general gene information for CD80. It may not necessarily be applicable to this product. NCBI GI # 27503576 NCBI GeneID 941 NCBI Accession # AAH42665.1 [Other Products] UniProt Secondary Accession # Q5DTA9; Q5DTB0[Other Products] UniProt Related Accession # P33681[Other Products] Molecular Weight 18,761 Da[Similar Products] TOP NCBI Official Full Name CD80 molecule NCBI Official Synonym Full Names CD80 molecule NCBI Official Symbol CD80 [Similar Products] NCBI Official Synonym Symbols B7; BB1; B7-1; B7.1; LAB7; CD28LG; CD28LG1 [Similar Products] NCBI Protein Information T-lymphocyte activation antigen CD80; activation B7-1 antigen; costimulatory factor CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; costimulatory molecule variant IgV-CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) UniProt Protein Name T-lymphocyte activation antigen CD80 UniProt Synonym Protein Names Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD_antigen: CD80 Protein Family T-lymphocyte activation antigen UniProt Gene Name CD80 [Similar Products] UniProt Synonym Gene Names CD28LG; CD28LG1; LAB7; B7 [Similar Products] UniProt Entry Name CD80_HUMAN TOP NCBI Summary for CD80 The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011] TOP UniProt Comments for CD80 CD80: Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.Protein type: Membrane protein, integral; Immunoglobulin superfamilyChromosomal Location of Human Ortholog: 3q13.3-q21Cellular Component: cell surface; plasma membrane; integral to membrane; external side of plasma membraneMolecular Function: protein binding; coreceptor activityBiological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; viral reproduction; positive regulation of signal transduction; nerve growth factor receptor signaling pathway; T cell activation; positive regulation of transcription, DNA-dependent; positive regulation of interleukin-2 biosynthetic process; positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process; positive regulation of peptidyl-tyrosine phosphorylation; cell-cell signaling; T cell costimulation; innate immune response; positive regulation of alpha-beta T cell proliferation; positive regulation of T-helper 1 cell differentiation Research Articles on CD80 1. Expression of costimulatory molecules CD80/86 is an absolute requirement for efficient CD8 T cell priming by adenoviral vectors. TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-CD80 antibody Reference Product PubMed Publications CD86 antibody >4655 publications with CD80 and CD86 CD4 antibody >2103 publications with CD80 and CD4 CD28 antibody >1802 publications with CD80 and CD28 CTLA4 antibody >1009 publications with CD80 and CTLA4 ICAM1 antibody >415 publications with CD80 and ICAM1 PRF1 antibody >62 publications with CD80 and PRF1 IFNG antibody >6 publications with CD80 and IFNG CSF2 antibody >2 publications with CD80 and CSF2 Pathways associated with anti-CD80 antibody Products by Pathway Pathway Diagram Adaptive Immune System Pathway antibodies Adaptive Immune System Pathway Diagram Allograft Rejection Pathway antibodies Allograft Rejection Pathway Diagram Allograft Rejection Pathway antibodies Allograft Rejection Pathway Diagram Allograft Rejection Pathway antibodies Allograft Rejection Pathway Diagram Autoimmune Thyroid Disease Pathway antibodies Autoimmune Thyroid Disease Pathway Diagram Autoimmune Thyroid Disease Pathway antibodies Autoimmune Thyroid Disease Pathway Diagram CD28 Co-stimulation Pathway antibodies CD28 Co-stimulation Pathway Diagram CD28 Dependent PI3K/Akt Signaling Pathway antibodies CD28 Dependent PI3K/Akt Signaling Pathway Diagram CD28 Dependent Vav1 Pathway antibodies CD28 Dependent Vav1 Pathway Diagram CTLA4 Inhibitory Signaling Pathway antibodies CTLA4 Inhibitory Signaling Pathway Diagram Diseases associated with anti-CD80 antibody Disease Name Pubmed Publications Necrosis Antibodies >1100 publications with CD80 and Necrosis Inflammation Antibodies >731 publications with CD80 and Inflammation Neoplasms, Experimental Antibodies >377 publications with CD80 and Neoplasms, Experimental Nervous System Diseases Antibodies >342 publications with CD80 and Nervous System Diseases Lung Diseases Antibodies >301 publications with CD80 and Lung Diseases Liver Diseases Antibodies >221 publications with CD80 and Liver Diseases Kidney Diseases Antibodies >149 publications with CD80 and Kidney Diseases Lung Neoplasms Antibodies >110 publications with CD80 and Lung Neoplasms Neoplasm Metastasis Antibodies >81 publications with CD80 and Neoplasm Metastasis Breast Neoplasms Antibodies >80 publications with CD80 and Breast Neoplasms Organs/Tissues associated with anti-CD80 antibody Organ/Tissue Name Pubmed Publications Blood Antibodies >5870 publications with CD80 and Blood Lymph Node Antibodies >576 publications with CD80 and Lymph Node Lung Antibodies >413 publications with CD80 and Lung Thymus Antibodies >177 publications with CD80 and Thymus Tonsil Antibodies >39 publications with CD80 and Tonsil Connective Tissue Antibodies >33 publications with CD80 and Connective Tissue Mammary Gland Antibodies >4 publications with CD80 and Mammary Gland TOP © 2006-24 MyBioSource.com. 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