NP_001020331.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 92 kDa Predicted: 92 kDa
NCBI Official Full Name
CD97 antigen isoform 3 preproprotein
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor E5
NCBI Official Synonym Symbols
NCBI Protein Information
CD97 antigen
UniProt Protein Name
CD97 antigen
UniProt Synonym Protein Names
Leukocyte antigen CD97; CD_antigen: CD97
NCBI Summary for CD97
This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011]
UniProt Comments for CD97
Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration ().
Research Articles on CD97
Precautions
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Disclaimer
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Products associated with anti-CD97 antibody
Pathways associated with anti-CD97 antibody
Diseases associated with anti-CD97 antibody
Organs/Tissues associated with anti-CD97 antibody
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