NP_056975.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
65,521 Da
NCBI Official Full Name
pre-mRNA-processing factor 17
NCBI Official Synonym Full Names
cell division cycle 40
NCBI Protein Information
pre-mRNA-processing factor 17; hPRP17; PRP17 homolog; EH-binding protein 3; pre-mRNA splicing factor 17; cell division cycle 40 homolog
UniProt Protein Name
Pre-mRNA-processing factor 17
UniProt Synonym Protein Names
Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; PRP17 homolog; hPRP17
UniProt Synonym Gene Names
UniProt Entry Name
PRP17_HUMAN
NCBI Summary for CDC40
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression. [provided by RefSeq, Jul 2008]
UniProt Comments for CDC40
CDC40: Associates with the spliceosome late in the splicing pathway and may function in the second step of pre-mRNA splicing.
Protein type: RNA splicing; Motility/polarity/chemotaxis; Spliceosome; RNA processing
Chromosomal Location of Human Ortholog: 6q21
Cellular Component: nucleoplasm; spliceosome
Molecular Function: protein binding
Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; mRNA export from nucleus; RNA splicing; gene expression; mRNA 3'-end processing; termination of RNA polymerase II transcription
Research Articles on CDC40
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Products associated with anti-CDC40 antibody
Pathways associated with anti-CDC40 antibody
Diseases associated with anti-CDC40 antibody
Organs/Tissues associated with anti-CDC40 antibody
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