NP_001245.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
cell division control protein 6 homolog
NCBI Official Synonym Full Names
cell division cycle 6
NCBI Official Synonym Symbols
CDC18L; HsCDC6; MGORS5; HsCDC18 [Similar Products]
NCBI Protein Information
cell division control protein 6 homolog
UniProt Protein Name
Cell division control protein 6 homolog
UniProt Synonym Protein Names
CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6
UniProt Synonym Gene Names
NCBI Summary for CDC6
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008]
UniProt Comments for CDC6
Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
Research Articles on CDC6
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Products associated with anti-CDC6 antibody
Pathways associated with anti-CDC6 antibody
Diseases associated with anti-CDC6 antibody
Organs/Tissues associated with anti-CDC6 antibody
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