NP_689775.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
7,241 Da
NCBI Official Full Name
cell division cycle-associated protein 2
NCBI Official Synonym Full Names
cell division cycle associated 2
NCBI Protein Information
cell division cycle-associated protein 2
UniProt Protein Name
Cell division cycle-associated protein 2
UniProt Synonym Protein Names
Recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man
UniProt Synonym Gene Names
UniProt Entry Name
CDCA2_HUMAN
UniProt Comments for CDCA2
CDCA2: Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 8p21.2
Cellular Component: nucleoplasm; cytoplasm; chromosome
Biological Process: mitosis; cell division; positive regulation of protein amino acid dephosphorylation; chromosome segregation
Research Articles on CDCA2
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Products associated with anti-CDCA2 antibody
Diseases associated with anti-CDCA2 antibody
Organs/Tissues associated with anti-CDCA2 antibody
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