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anti-CDX1 antibody :: Rabbit anti-Human, Rat CDX1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7051841
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CDX1, Polyclonal Antibody

★Popular Item★
 Also Known As   

CDX1 Antibody

 Product Synonym Names    Homeobox protein CDX-1; Caudal-type homeobox protein 1; CDX1
 Product Gene Name   

anti-CDX1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    U16360 Genomic DNA
 3D Structure    ModBase 3D Structure for P47902
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Rat
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant Human Homeobox protein CDX-1 protein (206-245AA)
 Conjugation    Non-conjugated
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, pH 7.4
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CDX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CDX1 antibody

   Plays a role in transcriptional regulation (PubMed:24623306). Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306). Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306). Could play a role in the terminal differentiation of the intestine.
 Applications Tested/Suitable for anti-CDX1 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

 Application Notes for anti-CDX1 antibody    WB: 1:500-1:5000
IF: 1:50-1:200
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 Western Blot (WB) of anti-CDX1 antibody    Western Blot
Positive WB detected in: Rat liver tissue
All lanes: CDX1 antibody at 4ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 29,15 KDa
Observed band size: 29 KDa

anti-CDX1 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-CDX1 antibody    Immunofluorescent analysis of Hela cells using MBS7051841 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-CDX1 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for CDX1. It may not necessarily be applicable to this product.
 NCBI GI #    121114296
 NCBI GeneID    1044
 NCBI Accession #    NP_001795.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001804.2 [Other Products]
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 UniProt Primary Accession #    P47902 [Other Products]
 UniProt Secondary Accession #    Q4VAU4; Q9NYK8 [Other Products]
 UniProt Related Accession #    P47902 [Other Products]
 Molecular Weight    14,661 Da
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 NCBI Official Full Name    homeobox protein CDX-1
 NCBI Official Synonym Full Names    caudal type homeobox 1
 NCBI Official Symbol    CDX1 [Similar Products]
 NCBI Protein Information    homeobox protein CDX-1
 UniProt Protein Name    Homeobox protein CDX-1
 UniProt Synonym Protein Names   
Caudal-type homeobox protein 1
 Protein Family    Homeobox protein
 UniProt Gene Name    CDX1 [Similar Products]
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 NCBI Summary for CDX1    This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CDX1    CDX1: Could play a role in the terminal differentiation of the intestine. Belongs to the Caudal homeobox family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: nucleus

Molecular Function: protein binding

Biological Process: anterior/posterior axis specification; cell differentiation; organ morphogenesis; positive regulation of transcription from RNA polymerase II promoter; regulation of somitogenesis
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 Research Articles on CDX1    1. Data indicate an association between highly fucosylated glycans and caudal type homeobox 1 (CDX1) and/or villin mRNA expression that both correlate with cell differentiation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CDX1 antibodyPathways associated with anti-CDX1 antibody
 Reference Product  PubMed Publications
 LEF1 antibody  >7 publications with CDX1 and LEF1
 CEBPA antibody  >1 publications with CDX1 and CEBPA
 Products by Pathway  Pathway Diagram
 Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway antibodies  Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway Diagram
Diseases associated with anti-CDX1 antibodyOrgans/Tissues associated with anti-CDX1 antibody
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >82 publications with CDX1 and Neoplasms
 Leukemia Antibodies  >8 publications with CDX1 and Leukemia
 Embryo Loss Antibodies  >7 publications with CDX1 and Embryo Loss
 Disease Models, Animal Antibodies  >5 publications with CDX1 and Disease Models, Animal
 Head and Neck Neoplasms Antibodies  >5 publications with CDX1 and Head and Neck Neoplasms
 Leukemia, Myeloid Antibodies  >4 publications with CDX1 and Leukemia, Myeloid
 Liver Neoplasms Antibodies  >4 publications with CDX1 and Liver Neoplasms
 Pancreatic Neoplasms Antibodies  >4 publications with CDX1 and Pancreatic Neoplasms
 Leukemia, Myeloid, Acute Antibodies  >4 publications with CDX1 and Leukemia, Myeloid, Acute
 Carcinoma, Squamous Cell Antibodies  >3 publications with CDX1 and Carcinoma, Squamous Cell
 Organ/Tissue Name  Pubmed Publications
 Intestine Antibodies  >103 publications with CDX1 and Intestine
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