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anti-CEACAM1 antibody :: Rabbit anti-Human CEACAM1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7000563
Western Blot (WB)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CEACAM1, Polyclonal Antibody

★Popular Item★
 Also Known As   

CEACAM1 Antibody

 Product Synonym Names    Carcinoembryonic antigen-related cell adhesion molecule 1; CEACAM1; BGP; BGP1; Biliary glycoprotein 1; BGP-1; CD_antigen: CD66a
 Product Gene Name   

anti-CEACAM1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    109770
 3D Structure    ModBase 3D Structure for P13688
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Affinity Purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Carcinoembryonic antigen-related cell adhesion molecule 1 protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-54289 / sc-54287 / sc-17068 / sc-8222 / sc-8223 / sc-25627
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CEACAM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CEACAM1 antibody

   extracellular exosome, integral component of membrane, integral component of plasma membrane, membrane, plasma membrane, protein homodimerization activity, angiogenesis, blood coagulation, cell migration, homophilic cell adhesion via plasma membrane adhesion molecules
 Applications Tested/Suitable for anti-CEACAM1 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-CEACAM1 antibody    Recommended dilution: WB:1:500-2000
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 Western Blot (WB) of anti-CEACAM1 antibody    Western blot
All lanes: CEACAM1 antibody at 10ug/ml
Lane 1: HT29 whole cell lysate
Lane 2: HCT116 whole cell lysate
Lane 3: COLO205 whole cell lysate
Lane 4: HepG-2 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 58,46,36,39,51,47,28,44,52 kDa
Observed band size: 58 kDa

anti-CEACAM1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CEACAM1. It may not necessarily be applicable to this product.
 NCBI GI #    68161541
 NCBI GeneID    634
 NCBI Accession #    NP_001020083.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001024912.2 [Other Products]
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 UniProt Primary Accession #    P13688 [Other Products]
 UniProt Secondary Accession #    O60430; Q069I7; Q13854; Q13857; Q13858; Q13859; Q13860; Q15600; Q15601; A6NE38; A8MY49 [Other Products]
 UniProt Related Accession #    P13688 [Other Products]
 Molecular Weight    39,871 Da
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 NCBI Official Full Name    carcinoembryonic antigen-related cell adhesion molecule 1 isoform 2
 NCBI Official Synonym Full Names    carcinoembryonic antigen related cell adhesion molecule 1
 NCBI Official Symbol    CEACAM1 [Similar Products]
 NCBI Official Synonym Symbols   
BGP; BGP1; BGPI
[Similar Products]
 NCBI Protein Information    carcinoembryonic antigen-related cell adhesion molecule 1
 UniProt Protein Name    Carcinoembryonic antigen-related cell adhesion molecule 1
 UniProt Synonym Protein Names   
Biliary glycoprotein 1; BGP-1; CD_antigen: CD66a
 Protein Family    CEACAM1-like protein
 UniProt Gene Name    CEACAM1 [Similar Products]
 UniProt Synonym Gene Names    BGP; BGP1; BGP-1 [Similar Products]
 UniProt Entry Name    CEAM1_HUMAN
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 NCBI Summary for CEACAM1    This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. [provided by RefSeq, May 2010]
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 UniProt Comments for CEACAM1    CEACAM1: carcinoembryonic antigen-related cell adhesion molecule 1. A cell-cell adhesion molecule that directly associates with annexin II. Has tumor suppressor activity in prostate carcinoma. Belongs to the immunoglobulin superfamily and the CEA family. Abundantly expressed in epithelia, vessel endothelia, trophoblasts, platelets and neutrophilic granulocytes. Also present in many cell types of the immune system such as B cells, T cells, NK cells, macrophages and dendritic cells. Five alternatively spliced isoforms have been described. Two isoforms are type I membrane proteins, while three are secreted.

Protein type: Immunoglobulin superfamily; Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: integral to membrane; integral to plasma membrane; membrane; plasma membrane

Molecular Function: protein binding; protein homodimerization activity

Biological Process: angiogenesis; blood coagulation; cell migration; homophilic cell adhesion; integrin-mediated signaling pathway; leukocyte migration
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 Research Articles on CEACAM1    1. High levels of serum CEA, CA72-4, CA19-9 and TSGF are associated with Gastric Cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CEACAM1 antibodyPathways associated with anti-CEACAM1 antibody
 Reference Product  PubMed Publications
 CEACAM6 antibody  >54 publications with CEACAM1 and CEACAM6
 CEACAM8 antibody  >21 publications with CEACAM1 and CEACAM8
 PTPN11 antibody  >7 publications with CEACAM1 and PTPN11
 VEGFA antibody  >4 publications with CEACAM1 and VEGFA
 SOX9 antibody  >4 publications with CEACAM1 and SOX9
 ZAP70 antibody  >2 publications with CEACAM1 and ZAP70
 CRH antibody  >1 publications with CEACAM1 and CRH
 LCK antibody  >1 publications with CEACAM1 and LCK
 CD209 antibody  >1 publications with CEACAM1 and CD209
 Products by Pathway  Pathway Diagram
 Cell Surface Interactions At The Vascular Wall Pathway antibodies  Cell Surface Interactions At The Vascular Wall Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Extracellular Matrix Organization Pathway antibodies  Extracellular Matrix Organization Pathway Diagram
 Fibronectin Matrix Formation Pathway antibodies  Fibronectin Matrix Formation Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
Diseases associated with anti-CEACAM1 antibodyOrgans/Tissues associated with anti-CEACAM1 antibody
 Disease Name  Pubmed Publications
 Adenocarcinoma Antibodies  >58 publications with CEACAM1 and Adenocarcinoma
 Inflammation Antibodies  >50 publications with CEACAM1 and Inflammation
 Liver Diseases Antibodies  >41 publications with CEACAM1 and Liver Diseases
 Neoplasm Metastasis Antibodies  >36 publications with CEACAM1 and Neoplasm Metastasis
 Liver Neoplasms Antibodies  >36 publications with CEACAM1 and Liver Neoplasms
 Lung Neoplasms Antibodies  >35 publications with CEACAM1 and Lung Neoplasms
 Lung Diseases Antibodies  >34 publications with CEACAM1 and Lung Diseases
 Breast Neoplasms Antibodies  >32 publications with CEACAM1 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >21 publications with CEACAM1 and Neoplasms, Experimental
 Necrosis Antibodies  >20 publications with CEACAM1 and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >282 publications with CEACAM1 and Blood
 Liver Antibodies  >121 publications with CEACAM1 and Liver
 Lung Antibodies  >61 publications with CEACAM1 and Lung
 Intestine Antibodies  >46 publications with CEACAM1 and Intestine
 Kidney Antibodies  >40 publications with CEACAM1 and Kidney
 Brain Antibodies  >27 publications with CEACAM1 and Brain
 Muscle Antibodies  >25 publications with CEACAM1 and Muscle
 Skin Antibodies  >22 publications with CEACAM1 and Skin
 Lymph Node Antibodies  >19 publications with CEACAM1 and Lymph Node
 Placenta Antibodies  >17 publications with CEACAM1 and Placenta
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