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anti-CECR2 antibody :: Goat CECR2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS421499 anti-CECR2 antibody
Unit / Price
0.1 mg  /  $225 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CECR2, Polyclonal Antibody

 Also Known As   

Goat anti-CECR2 Antibody

 Product Synonym Names    CECR2; cat eye syndrome chromosome region, candidate 2; KIAA1740; CECR2 antibody; cat eye syndrome chromosome region; candidate 2 antibody; KIAA1740 antibody
 Product Gene Name   

anti-CECR2 antibody

[Similar Products]
 Antibody/Peptide Pairs    CECR2 peptide (MBS426207) is used for blocking the activity of CECR2 antibody (MBS421499)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    PPHKPPTLPL DQS
 OMIM    607576
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Expected from sequence similarity: Human, Dog
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-PPHKPPTLPLDQS, from the C Terminus of the protein sequence according to AAK15343.1.
 Epitope    C Terminus
 Note    The peptide sequence used (from AAK15343.1) differs by one residue from the RefSeq entry (XP_931107.2). It is not known whether this difference is due to a sequencing error or polymophism but the antibody is expected to recognize both sequences.
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-CECR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CECR2 antibody   

Peptide ELISA (EIA)

 Application Notes for anti-CECR2 antibody    Peptide ELISA: Antibody detection limit dilution 1: 32000.
Western Blot: No signal obtained yet but low background observed in human testis and 293 lysates at up to 1ug/ml.
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NCBI/Uniprot data below describe general gene information for CECR2. It may not necessarily be applicable to this product.
 NCBI GI #    13183793
 NCBI GeneID    27443
 NCBI Accession #    AAK15343.1 [Other Products]
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 UniProt Secondary Accession #    Q658Z4; Q96P58; Q9C0C3; A8MS90; A8MX16 [Other Products]
 UniProt Related Accession #    Q9BXF3 [Other Products]
 Molecular Weight    162,067 Da
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 NCBI Official Full Name    CECR2 protein
 NCBI Official Synonym Full Names    CECR2, histone acetyl-lysine reader
 NCBI Official Symbol    CECR2 [Similar Products]
 NCBI Protein Information    cat eye syndrome critical region protein 2
 UniProt Protein Name    Cat eye syndrome critical region protein 2
 Protein Family    Cat eye syndrome critical region protein
 UniProt Gene Name    CECR2 [Similar Products]
 UniProt Synonym Gene Names    KIAA1740 [Similar Products]
 UniProt Entry Name    CECR2_HUMAN
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 NCBI Summary for CECR2    This gene encodes a bromodomain-containing protein that is involved in chromatin remodeling, and may additionally play a role in DNA damage response. The encoded protein functions as part of an ATP-dependent complex that is involved in neurulation. This gene is a candidate gene for Cat Eye Syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]
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 UniProt Comments for CECR2    CECR2: Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Chromosomal Location of Human Ortholog: 22q11.2

Cellular Component: nucleus

Molecular Function: protein binding

Biological Process: ATP-dependent chromatin remodeling; cytokinesis; cytoskeleton organization and biogenesis; DNA fragmentation during apoptosis; neural tube development; vesicle-mediated transport
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 Research Articles on CECR2    1. The genes CECR2, SLC25A18 and ATP6V1E1, mapping within the critical region for cat eye syndrome (CES), may be responsible for anorectal, renal and preauricular anomalies in patients with CES.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CECR2 antibodyDiseases associated with anti-CECR2 antibody
 Reference Product  PubMed Publications
 SMARCA1 antibody  >1 publications with CECR2 and SMARCA1
 SMARCA5 antibody  >1 publications with CECR2 and SMARCA5
 Disease Name  Pubmed Publications
 Neural Tube Defects Antibodies  >7 publications with CECR2 and Neural Tube Defects
 Nervous System Diseases Antibodies  >5 publications with CECR2 and Nervous System Diseases
 Infertility, Male Antibodies  >2 publications with CECR2 and Infertility, Male
 Male Urogenital Diseases Antibodies  >2 publications with CECR2 and Male Urogenital Diseases
 Abnormalities, Multiple Antibodies  >1 publications with CECR2 and Abnormalities, Multiple
 Inflammation Antibodies  >1 publications with CECR2 and Inflammation
 Urogenital Abnormalities Antibodies  >1 publications with CECR2 and Urogenital Abnormalities
 Carcinoma, Hepatocellular Antibodies  >1 publications with CECR2 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with CECR2 and Liver Neoplasms
 Liver Diseases Antibodies  >1 publications with CECR2 and Liver Diseases
Organs/Tissues associated with anti-CECR2 antibody
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >3 publications with CECR2 and Testis
 Embryonic Tissue Antibodies  >3 publications with CECR2 and Embryonic Tissue
 Brain Antibodies  >2 publications with CECR2 and Brain
 Bone Antibodies  >1 publications with CECR2 and Bone
 Nerve Antibodies  >1 publications with CECR2 and Nerve
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