NP_001398.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
cadherin EGF LAG seven-pass G-type receptor 3
NCBI Official Synonym Full Names
cadherin, EGF LAG seven-pass G-type receptor 3
NCBI Official Synonym Symbols
FMI1; EGFL1; HFMI1; MEGF2; ADGRC3; CDHF11; RESDA1 [Similar Products]
NCBI Protein Information
cadherin EGF LAG seven-pass G-type receptor 3
UniProt Protein Name
Cadherin EGF LAG seven-pass G-type receptor 3
UniProt Synonym Protein Names
Cadherin family member 11; Epidermal growth factor-like protein 1; EGF-like protein 1; Flamingo homolog 1; hFmi1; Multiple epidermal growth factor-like domains protein 2; Multiple EGF-like domains protein 2
UniProt Synonym Gene Names
CDHF11; EGFL1; FMI1; KIAA0812; MEGF2; EGF-like protein 1; hFmi1; Multiple EGF-like domains protein 2 [Similar Products]
UniProt Entry Name
CELR3_HUMAN
NCBI Summary for CELSR3
This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013]
UniProt Comments for CELSR3
CELSR3: Receptor that may have an important role in cell/cell signaling during nervous system formation. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: GPCR, family 2; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 3p21.31
Cellular Component: integral to membrane; plasma membrane
Molecular Function: G-protein coupled receptor activity; protein binding; calcium ion binding
Biological Process: G-protein coupled receptor protein signaling pathway; regulation of protein localization; axonal fasciculation; neuron migration; cilium biogenesis; homophilic cell adhesion
Research Articles on CELSR3
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Products associated with anti-CELSR3 antibody
Pathways associated with anti-CELSR3 antibody
Diseases associated with anti-CELSR3 antibody
Organs/Tissues associated with anti-CELSR3 antibody
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