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anti-CEP120 antibody :: Rabbit anti-Human, Rat CEP120 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS9127987
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CEP120, Polyclonal Antibody

 Also Known As   

CEP120 Polyclonal Antibody

 Product Gene Name   

anti-CEP120 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    613446
 3D Structure    ModBase 3D Structure for Q8N960
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Rat
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 Purity/Purification    Affinity Purification
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 Immunogen    Recombinant Protein
 Immunogen    Recombinant protein of human CEP120
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 Preparation and Storage    Store at -20 degree C. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Other Notes    Small volumes of anti-CEP120 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-CEP120 antibody

   This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants.
 Applications Tested/Suitable for anti-CEP120 antibody   

Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-CEP120 antibody    WB 1:500 - 1:2000
IHC 1:50 - 1:200
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 Western Blot (WB) of anti-CEP120 antibody    Western blot analysis of extracts of various cell lines, using CEP120 antibody.
anti-CEP120 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CEP120. It may not necessarily be applicable to this product.
 NCBI GI #    261245061
 NCBI GeneID    153241
 NCBI Accession #    NP_001159698.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001166226.1 [Other Products]
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 UniProt Primary Accession #    Q8N960 [Other Products]
 UniProt Secondary Accession #    Q6AI52; Q6AW89; Q8IWB5; Q8N9Y0; Q8NDE8 [Other Products]
 UniProt Related Accession #    Q8N960 [Other Products]
 Molecular Weight    113kDa
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 NCBI Official Full Name    centrosomal protein of 120 kDa isoform 2
 NCBI Official Synonym Full Names    centrosomal protein 120kDa
 NCBI Official Symbol    CEP120 [Similar Products]
 NCBI Official Synonym Symbols   
SRTD13; CCDC100
[Similar Products]
 NCBI Protein Information    centrosomal protein of 120 kDa
 UniProt Protein Name    Centrosomal protein of 120 kDa
 UniProt Synonym Protein Names   
Coiled-coil domain-containing protein 100
 Protein Family    Centrosomal protein
 UniProt Gene Name    CEP120 [Similar Products]
 UniProt Synonym Gene Names    CCDC100; Cep120 [Similar Products]
 UniProt Entry Name    CE120_HUMAN
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 NCBI Summary for CEP120    This gene encodes a protein that functions in the microtubule-dependent coupling of the nucleus and the centrosome. A similar protein in mouse plays a role in both interkinetic nuclear migration, which is a characteristic pattern of nuclear movement in neural progenitors, and in neural progenitor self-renewal. Mutations in this gene are predicted to result in neurogenic defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
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 UniProt Comments for CEP120    CEP120: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrenewal of neural progenitors. May play a role in centriole duplication during mitosis. Belongs to the CEP120 family. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 5q23.2

Cellular Component: centrosome; cytoplasm

Molecular Function: protein C-terminus binding

Biological Process: regulation of microtubule-based process; astral microtubule organization and biogenesis; regulation of protein localization; neurogenesis; cerebral cortex development; interkinetic nuclear migration

Disease: Short-rib Thoracic Dysplasia 13 With Or Without Polydactyly
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 Research Articles on CEP120    1. CEP120 associates with SPICE1 and CPAP, and depletion of any of these proteins results in short procentrioles. Furthermore, CEP120 or CPAP overexpression results in excessive centriole elongation, a process dependent on CEP120, SPICE1, and CPAP.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products related to CEP120 Polyclonal Antibody
 Catalog #  Product Name  Catalog #  Product Name
 MBS7235559  Mouse Centrosomal protein of 120 kDa (CEP120) ELISA Kit  MBS7247314  Rabbit Centrosomal protein of 120 kDa (CEP120) ELISA Kit
 MBS8232909  CEP120 siRNA (Human)  MBS7247610  Canine Centrosomal protein of 120 kDa (CEP120) ELISA Kit
 MBS7044616  CEP120 Antibody  MBS1337077  Recombinant Human Centrosomal protein of 120 kDa (CEP120), partial
 MBS7221424  Human Centrosomal protein of 120 kDa (CEP120) ELISA Kit  MBS962681  Recombinant Bovine Centrosomal protein of 120 kDa (CEP120), partial
 MBS9127987  CEP120 Polyclonal Antibody  MBS7237902  Rat Centrosomal protein of 120 kDa (CEP120) ELISA Kit
Products associated with anti-CEP120 antibodyDiseases associated with anti-CEP120 antibody
 Reference Product  PubMed Publications
 CEP152 antibody  >2 publications with CEP120 and CEP152
 CEP135 antibody  >2 publications with CEP120 and CEP135
 SPICE1 antibody  >1 publications with CEP120 and SPICE1
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >1 publications with CEP120 and Congenital Abnormalities
 Inflammation Antibodies  >1 publications with CEP120 and Inflammation
Organs/Tissues associated with anti-CEP120 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with CEP120 and Brain
 Embryonic Tissue Antibodies  >1 publications with CEP120 and Embryonic Tissue
 Heart Antibodies  >1 publications with CEP120 and Heart
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