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anti-CEP72 antibody :: Rabbit anti-Human CEP72 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7045030
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CEP72, Polyclonal Antibody

★Popular Item★
 Also Known As   

CEP72 Antibody

 Product Synonym Names    Centrosomal protein of 72 kDa; Cep72; CEP72; KIAA1519
 Product Gene Name   

anti-CEP72 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    616475
 3D Structure    ModBase 3D Structure for Q9P209
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Centrosomal protein of 72 kDa protein (200-460AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162680 / sc-162679
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CEP72 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CEP72 antibody

   Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs) (PubMed:19536135). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2 (PubMed:26297806).
 Applications Tested/Suitable for anti-CEP72 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-CEP72 antibody    Western blot
All lanes: CEP72 antibody at 3.37 ug/ml+ Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 72,22 kDa
Observed band size: 72,42 kDa

anti-CEP72 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CEP72 antibody    Immunohistochemistry of paraffin-embedded human testis tissue using MBS7045030 at dilution of 1:100
anti-CEP72 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CEP72. It may not necessarily be applicable to this product.
 NCBI GI #    62899065
 NCBI GeneID    55722
 NCBI Accession #    NP_060610.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_018140.3 [Other Products]
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 UniProt Primary Accession #    Q9P209 [Other Products]
 UniProt Secondary Accession #    Q9BV03; Q9BWM3; Q9NVR4; B4DR26 [Other Products]
 UniProt Related Accession #    Q9P209 [Other Products]
 Molecular Weight    21,336 Da
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 NCBI Official Full Name    centrosomal protein of 72 kDa
 NCBI Official Synonym Full Names    centrosomal protein 72
 NCBI Official Symbol    CEP72 [Similar Products]
 NCBI Protein Information    centrosomal protein of 72 kDa
 UniProt Protein Name    Centrosomal protein of 72 kDa
 Protein Family    Centrosomal protein
 UniProt Gene Name    CEP72 [Similar Products]
 UniProt Synonym Gene Names    KIAA1519; Cep72 [Similar Products]
 UniProt Entry Name    CEP72_HUMAN
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 NCBI Summary for CEP72    The product of this gene is a member of the leucine-rich-repeat (LRR) superfamily of proteins. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CEP72    CEP72: Involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ/PLK1S1, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs). Belongs to the CEP72 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding

Chromosomal Location of Human Ortholog: 5p15.33

Cellular Component: centrosome; cytosol

Molecular Function: protein binding

Biological Process: centriole replication; G2/M transition of mitotic cell cycle; gamma-tubulin complex localization; spindle organization and biogenesis
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 Research Articles on CEP72    1. In this study an inherited polymorphism in the promoter region of CEP72 was associated with increased risk and severity of vincristine-related peripheral neuropathy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CEP72 antibodyDiseases associated with anti-CEP72 antibody
 Products by Pathway  Pathway Diagram
 AURKA Activation By TPX2 Pathway antibodies  AURKA Activation By TPX2 Pathway Diagram
 Anchoring Of The Basal Body To The Plasma Membrane Pathway antibodies  Anchoring Of The Basal Body To The Plasma Membrane Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Cell Cycle Pathway antibodies  Cell Cycle Pathway Diagram
 Cell Cycle, Mitotic Pathway antibodies  Cell Cycle, Mitotic Pathway Diagram
 Centrosome Maturation Pathway antibodies  Centrosome Maturation Pathway Diagram
 G2/M Transition Pathway antibodies  G2/M Transition Pathway Diagram
 Loss Of Nlp From Mitotic Centrosomes Pathway antibodies  Loss Of Nlp From Mitotic Centrosomes Pathway Diagram
 Loss Of Proteins Required For Interphase Microtubule Organizationfrom The Centrosome Pathway antibodies  Loss Of Proteins Required For Interphase Microtubule Organizationfrom The Centrosome Pathway Diagram
 Mitotic G2-G2/M Phases Pathway antibodies  Mitotic G2-G2/M Phases Pathway Diagram
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >3 publications with CEP72 and Immune System Diseases
 Carcinoma Antibodies  >1 publications with CEP72 and Carcinoma
 Congenital Abnormalities Antibodies  >1 publications with CEP72 and Congenital Abnormalities
 Vascular Diseases Antibodies  >1 publications with CEP72 and Vascular Diseases
 Lung Neoplasms Antibodies  >1 publications with CEP72 and Lung Neoplasms
Organs/Tissues associated with anti-CEP72 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with CEP72 and Brain
 Bone Antibodies  >1 publications with CEP72 and Bone
 Bone Marrow Antibodies  >1 publications with CEP72 and Bone Marrow
 Lung Antibodies  >1 publications with CEP72 and Lung
 Blood Antibodies  >1 publications with CEP72 and Blood
 Esophagus Antibodies  >1 publications with CEP72 and Esophagus
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