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anti-CHGB antibody :: anti-Human, Mouse CHGB Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS126989
Western Blot (WB)
Unit / Price
0.05 mL  /  $230 +1 FREE 8GB USB
0.1 mL  /  $305 +1 FREE 8GB USB
0.2 mL  /  $460 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CHGB, Polyclonal Antibody

★Popular Item★
 Also Known As   

CHGB

 Product Synonym Names    SCG1
 Product Gene Name   

anti-CHGB antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    118920
 3D Structure    ModBase 3D Structure for P05060
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 Clonality    Polyclonal
 Isotype    IgG
 Species Reactivity    Human, Mouse
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 Purity/Purification    Affinity purification
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 Source    Rabbit
 Species    Human
 Immunogen    Recombinant protein of human CHGB
 Category    Primary antibody
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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 Preparation and Storage    Store at -20?. Avoid freeze / thaw cycles.
 Other Notes    Small volumes of anti-CHGB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CHGB antibody

   This gene encodes a tyrosine-s?lfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for reg?latory peptides.
 Product Categories/Family for anti-CHGB antibody    Polyclonal
 Applications Tested/Suitable for anti-CHGB antibody   

Western Blot (WB)

 Application Notes for anti-CHGB antibody    WB: 1:100 - 1:500
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 Western Blot (WB) of anti-CHGB antibody    Western blot analysis of extracts of various cell lines, using CHGB antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit.
Exposure time: 30s.
anti-CHGB antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CHGB. It may not necessarily be applicable to this product.
 NCBI GI #    311033509
 NCBI GeneID    1114
 NCBI Accession #    P05060.2 [Other Products]
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 UniProt Primary Accession #    P05060 [Other Products]
 UniProt Secondary Accession #    Q59EU9; Q6IBS6; Q9BQV6; Q9UC25; Q9UJA6; A8K021 [Other Products]
 UniProt Related Accession #    P05060 [Other Products]
 Molecular Weight    78kDa
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 NCBI Official Full Name    Secretogranin-1
 NCBI Official Synonym Full Names    chromogranin B (secretogranin 1)
 NCBI Official Symbol    CHGB [Similar Products]
 NCBI Official Synonym Symbols   
SCG1
[Similar Products]
 NCBI Protein Information    secretogranin-1; cgB; sgI; chromogranin-B; secretogranin B; secretogranin I
 UniProt Protein Name    Secretogranin-1
 UniProt Synonym Protein Names   
Chromogranin-B; CgB; Secretogranin I; SgI
 Protein Family    Secretogranin
 UniProt Gene Name    CHGB [Similar Products]
 UniProt Synonym Gene Names    SCG1; CgB; SgI [Similar Products]
 UniProt Entry Name    SCG1_HUMAN
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 NCBI Summary for CHGB    This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009]
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 UniProt Comments for CHGB    CHGB: a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 20p12.3

Cellular Component: extracellular region; secretory granule

Molecular Function: protein binding; hormone activity
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 Research Articles on CHGB    1. CgA and CgB have been used as general NEN biomarkers for many years, while CART has only recently been identified
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CHGB antibodyDiseases associated with anti-CHGB antibody
 Reference Product  PubMed Publications
 CHGA antibody  >28 publications with CHGB and CHGA
 CGB antibody  >21 publications with CHGB and CGB
 SCG2 antibody  >4 publications with CHGB and SCG2
 PHF21A antibody  >1 publications with CHGB and PHF21A
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >16 publications with CHGB and Nervous System Diseases
 Brain Diseases Antibodies  >11 publications with CHGB and Brain Diseases
 Hypertension Antibodies  >8 publications with CHGB and Hypertension
 Cardiovascular Diseases Antibodies  >6 publications with CHGB and Cardiovascular Diseases
 Liver Diseases Antibodies  >2 publications with CHGB and Liver Diseases
 Neoplasms, Experimental Antibodies  >2 publications with CHGB and Neoplasms, Experimental
 Hyperplasia Antibodies  >2 publications with CHGB and Hyperplasia
 Lung Neoplasms Antibodies  >1 publications with CHGB and Lung Neoplasms
 Liver Neoplasms Antibodies  >1 publications with CHGB and Liver Neoplasms
 Inflammation Antibodies  >1 publications with CHGB and Inflammation
Organs/Tissues associated with anti-CHGB antibody
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >22 publications with CHGB and Nerve
 Brain Antibodies  >17 publications with CHGB and Brain
 Adrenal Gland Antibodies  >15 publications with CHGB and Adrenal Gland
 Pancreas Antibodies  >11 publications with CHGB and Pancreas
 Pituitary Gland Antibodies  >8 publications with CHGB and Pituitary Gland
 Intestine Antibodies  >6 publications with CHGB and Intestine
 Embryonic Tissue Antibodies  >3 publications with CHGB and Embryonic Tissue
 Heart Antibodies  >2 publications with CHGB and Heart
 Muscle Antibodies  >2 publications with CHGB and Muscle
 Kidney Antibodies  >2 publications with CHGB and Kidney
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