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anti-CHI3L2 antibody :: Rabbit anti-Human, Rat CHI3L2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1492494
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CHI3L2, Polyclonal Antibody

★Popular Item★
 Also Known As   

CHI3L2 Antibody

 Product Synonym Names    Chondrocyte protein 39; YKL-39; CHI3L2
 Product Gene Name   

anti-CHI3L2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS1492494 Technical Datasheet    Technical Datasheet PDF
 OMIM    601526
 3D Structure    ModBase 3D Structure for Q15782
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Rat
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 Purity/Purification    Antigen Affinity Purified
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 Storage Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Chitinase-3-like protein 2 protein (27-390aa)
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-67991 / sc-68413
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CHI3L2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CHI3L2 antibody

   Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
 Applications Tested/Suitable for anti-CHI3L2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-CHI3L2 antibody    Recommended dilution: WB:1:500-2000
IHC:1:20-1:200
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 Western Blot (WB) of anti-CHI3L2 antibody    Western blot
All lanes: CHI3L2 antibody at 4ug/ml
Lane 1:Hela whole cell lysate
Lane 2:Rat brain tissue
Lane 3:A431 whole cell lysate
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 44,35,43 kDa
Observed band size: 44 kDa

anti-CHI3L2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CHI3L2 antibody    Immunohistochemistry of paraffin-embedded human tonsil tissue using MBS1492494 at dilution 1:100
anti-CHI3L2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CHI3L2 antibody    Immunohistochemistry of paraffin-embedded human rectum tissue using MBS1492494 at dilution 1:100
anti-CHI3L2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CHI3L2. It may not necessarily be applicable to this product.
 NCBI GI #    68533253
 NCBI GeneID    1117
 NCBI Accession #    NP_001020368.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001025197.1 [Other Products]
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 UniProt Primary Accession #    Q15782 [Other Products]
 UniProt Secondary Accession #    Q15749; Q15783; Q5VUV7; Q96F97; A6NNY3; B4DPR7 [Other Products]
 UniProt Related Accession #    Q15782 [Other Products]
 Molecular Weight    42,508 Da
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 NCBI Official Full Name    chitinase-3-like protein 2 isoform b
 NCBI Official Synonym Full Names    chitinase 3 like 2
 NCBI Official Symbol    CHI3L2 [Similar Products]
 NCBI Official Synonym Symbols   
CHIL2; YKL39; YKL-39
[Similar Products]
 NCBI Protein Information    chitinase-3-like protein 2
 UniProt Protein Name    Chitinase-3-like protein 2
 UniProt Synonym Protein Names   
Chondrocyte protein 39; YKL-39
 Protein Family    Chitinase-3-like protein
 UniProt Gene Name    CHI3L2 [Similar Products]
 UniProt Entry Name    CH3L2_HUMAN
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 NCBI Summary for CHI3L2    The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is secreted and is involved in cartilage biogenesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
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 UniProt Comments for CHI3L2    CHI3L2: Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity. Belongs to the glycosyl hydrolase 18 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 1p13.3

Cellular Component: extracellular space

Molecular Function: carbohydrate binding; chitin binding; chitinase activity

Biological Process: carbohydrate metabolic process; chitin catabolic process
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 Research Articles on CHI3L2    1. Structural analysis demonstrates that YKL-39 interacts with chitooligosaccharides through hydrogen bonds and hydrophobic interactions. Thermodynamic analysis indicates that binding of chitooligosaccharide to YKL-39 is mainly driven by enthalpy.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CHI3L2 antibodyDiseases associated with anti-CHI3L2 antibody
 Reference Product  PubMed Publications
 CHID1 antibody  >1 publications with CHI3L2 and CHID1
 Disease Name  Pubmed Publications
 Depressive Disorder Antibodies  >1 publications with CHI3L2 and Depressive Disorder
 Arthritis, Rheumatoid Antibodies  >1 publications with CHI3L2 and Arthritis, Rheumatoid
 Neoplasms, Experimental Antibodies  >1 publications with CHI3L2 and Neoplasms, Experimental
 Mental Disorders Antibodies  >1 publications with CHI3L2 and Mental Disorders
 Necrosis Antibodies  >1 publications with CHI3L2 and Necrosis
 Inflammation Antibodies  >1 publications with CHI3L2 and Inflammation
 Bone Resorption Antibodies  >1 publications with CHI3L2 and Bone Resorption
Organs/Tissues associated with anti-CHI3L2 antibody
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with CHI3L2 and Blood
 Brain Antibodies  >4 publications with CHI3L2 and Brain
 Bone Antibodies  >2 publications with CHI3L2 and Bone
 Skin Antibodies  >2 publications with CHI3L2 and Skin
 Lung Antibodies  >2 publications with CHI3L2 and Lung
 Kidney Antibodies  >1 publications with CHI3L2 and Kidney
 Spleen Antibodies  >1 publications with CHI3L2 and Spleen
 Heart Antibodies  >1 publications with CHI3L2 and Heart
 Ascites Antibodies  >1 publications with CHI3L2 and Ascites
 Connective Tissue Antibodies  >1 publications with CHI3L2 and Connective Tissue
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