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anti-chrna2a antibody :: Rabbit anti-Human CHRNA2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS643954 anti-chrna2a antibody
Unit / Price
0.2 mL  /  $550 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CHRNA2 (chrna2a), Polyclonal Antibody

 Also Known As   

CHRNA2, NT (CHRNA2, Neuronal acetylcholine receptor subunit alpha-2)

 Product Synonym Names    Anti -CHRNA2, NT (CHRNA2, Neuronal acetylcholine receptor subunit alpha-2)
 Product Gene Name   

anti-chrna2a antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Chromosome Location    Chromosome: 17; NC_007128.5 (5843715..5865654). Location: chromosome: 17
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Human
 Purity/Purification    Affinity Purified
Purified by Protein A affinity chromatography.
 Form/Format    Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
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 Immunogen    CHRNA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human CHRNA2.
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 Preparation and Storage    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
 Other Notes    Small volumes of anti-chrna2a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-chrna2a antibody

   Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels formed by a pentameric arrangement of alpha and beta subunits to create distinct muscle and neuronal receptors. Neuronal receptors are found throughout the peripheral and central nervous system where they are involved in fast synaptic transmission. This gene encodes an alpha subunit that is widely expressed in the brain. The proposed structure for nAChR subunits is a conserved N-terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C-terminal extracellular region. Mutations in this gene cause autosomal dominant nocturnal frontal lobe epilepsy type 4. Single nucleotide polymorphisms (SNPs) in this gene have been associated with nicotine dependence.
 Product Categories/Family for anti-chrna2a antibody    Antibodies; Abs to Receptors
 Applications Tested/Suitable for anti-chrna2a antibody   

ELISA (EL/EIA), Western Blot (WB)

 Application Notes for anti-chrna2a antibody    Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
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NCBI/Uniprot data below describe general gene information for chrna2a. It may not necessarily be applicable to this product.
 NCBI GI #    94536936
 NCBI GeneID    678575
 NCBI Accession #    NP_001035417.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001040327.1 [Other Products]
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 NCBI Official Full Name    cholinergic receptor, nicotinic, alpha polypeptide 2a
 NCBI Official Synonym Full Names    cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)
 NCBI Official Symbol    chrna2a [Similar Products]
 NCBI Official Synonym Symbols   
chrna2; zgc:136717
[Similar Products]
 NCBI Protein Information    cholinergic receptor, nicotinic, alpha polypeptide 2a; cholinergic receptor, nicotinic, alpha polypeptide 2 (neuronal)
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-chrna2a antibody
 Products by Pathway  Pathway Diagram
 Acetylcholine Binding And Downstream Events Pathway antibodies  Acetylcholine Binding And Downstream Events Pathway Diagram
 Activation Of Nicotinic Acetylcholine Receptors Pathway antibodies  Activation Of Nicotinic Acetylcholine Receptors Pathway Diagram
 Highly Calcium Permeable Nicotinic Acetylcholine Receptors Pathway antibodies  Highly Calcium Permeable Nicotinic Acetylcholine Receptors Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuronal System Pathway antibodies  Neuronal System Pathway Diagram
 Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway antibodies  Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Pathway Diagram
 Presynaptic Nicotinic Acetylcholine Receptors Pathway antibodies  Presynaptic Nicotinic Acetylcholine Receptors Pathway Diagram
 Transmission Across Chemical Synapses Pathway antibodies  Transmission Across Chemical Synapses Pathway Diagram
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