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Add To Compare List anti-CHST3 antibody :: Rabbit anti-Human CHST3 Polyclonal Antibody Catalog # MBS9609646 Unit / Price 0.1 mL / $270 +1 FREE 8GB USB 0.2 mL / $315 +1 FREE 8GB USB 5x0.2 mL / $1,245 +1 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name CHST3, Polyclonal Antibody Popular Item Full Product Name CHST3 Antibody Product Synonym Names C6ST 1; C6ST; C6ST-1; C6ST1; Carbohydrate (chondroitin 6) sulfotransferase 3; Carbohydrate sulfotransferase 3; Chondroitin 6 O sulfotransferase 1; Chondroitin 6 sulfotransferase; Chondroitin 6-O-sulfotransferase 1; Chondroitin 6-sulfotransferase; CHST 3; Chst3; CHST3_HUMAN; Galactose/N acetylglucosamine/N acetylglucosamine 6 O sulfotransferase 0; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0; GST 0; GST-0; GST0 Product Gene Name anti-CHST3 antibody[Similar Products] Antibody/Peptide Pairs CHST3 peptide (MBS9628350) is used for blocking the activity of CHST3 antibody (MBS9609646) Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP 3D Structure ModBase 3D Structure for Q7LGC8 Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human Specificity CHST3 antibody detects endogenous levels of total CHST3 Purity/Purification The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin. Form/Format LiquidPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Concentration 1mg/ml (lot specific) Immunogen A synthesized peptide derived from human CHST3 Subcellular Location Golgi Apparatus Tissue Specificity Widely expressed in adult tissues. Expressed in heart, placenta, skeletal muscle and pancreas. Also expressed in various immune tissues such as spleen, lymph node, thymus and appendix. Conjugation Unconjugated Preparation and Storage Store at -20 degree C. Stable for 12 months from date of receipt. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Supply Chain Verification Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire. Other Notes Small volumes of anti-CHST3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-CHST3 antibody Function: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen.Similarity: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily. Applications Tested/Suitable for anti-CHST3 antibody Western Blot (WB), ELISA (EIA) Application Notes for anti-CHST3 antibody WB: 1:1000-3000 Western Blot (WB) of anti-CHST3 antibody Western blot analysis of CHST3 using Jurkat whole cell lysates TOP NCBI/Uniprot data below describe general gene information for CHST3. It may not necessarily be applicable to this product. NCBI GI # 19923281 NCBI GeneID 9469 NCBI Accession # NP_004264.2 [Other Products] NCBI GenBank Nucleotide # NM_004273.4 [Other Products] UniProt Primary Accession # Q7LGC8 [Other Products] UniProt Secondary Accession # O75099; Q52M30[Other Products] UniProt Related Accession # Q7LGC8[Other Products] Molecular Weight Observed: 55 kDaPredicted: 55 kDa TOP NCBI Official Full Name carbohydrate sulfotransferase 3 NCBI Official Synonym Full Names carbohydrate sulfotransferase 3 NCBI Official Symbol CHST3 [Similar Products] NCBI Official Synonym Symbols HSD; C6ST; C6ST1 [Similar Products] NCBI Protein Information carbohydrate sulfotransferase 3 UniProt Protein Name Carbohydrate sulfotransferase 3 UniProt Synonym Protein Names Chondroitin 6-O-sulfotransferase 1; C6ST-1; Chondroitin 6-sulfotransferase; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0; GST-0 Protein Family Carbohydrate sulfotransferase UniProt Gene Name CHST3 [Similar Products] UniProt Synonym Gene Names C6ST-1; GST-0 [Similar Products] TOP NCBI Summary for CHST3 This gene encodes an enzyme which catalyzes the sulfation of chondroitin, a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation. Mutations in this gene are associated with spondylepiphyseal dysplasia and humerospinal dysostosis. [provided by RefSeq, Mar 2009] TOP UniProt Comments for CHST3 Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N-acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen. Research Articles on CHST3 1. We describe three consanguineous Indian families with a distinct form of spondyloepiphyseal dysplasia (SED Omani type). It is an autosomal recessive disorder due to mutation in CHST3 gene. 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TOP Pathways associated with anti-CHST3 antibody Products by Pathway Pathway Diagram Chondroitin Sulfate Biosynthesis Pathway antibodies Chondroitin Sulfate Biosynthesis Pathway Diagram Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram Disease Pathway antibodies Disease Pathway Diagram Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway antibodies Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway Diagram Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway antibodies Glycosaminoglycan Biosynthesis - Chondroitin Sulfate / Dermatan Sulfate Pathway Diagram Glycosaminoglycan Metabolism Pathway antibodies Glycosaminoglycan Metabolism Pathway Diagram MPS I - Hurler Syndrome Pathway antibodies MPS I - Hurler Syndrome Pathway Diagram MPS II - Hunter Syndrome Pathway antibodies MPS II - Hunter Syndrome Pathway Diagram MPS IIIA - Sanfilippo Syndrome A Pathway antibodies MPS IIIA - Sanfilippo Syndrome A Pathway Diagram MPS IIIB - Sanfilippo Syndrome B Pathway antibodies MPS IIIB - Sanfilippo Syndrome B Pathway Diagram Diseases associated with anti-CHST3 antibody Disease Name Pubmed Publications Congenital Abnormalities Antibodies >5 publications with CHST3 and Congenital Abnormalities Inflammation Antibodies >3 publications with CHST3 and Inflammation SPONDYLOEPIPHYSEAL DYSPLASIA WITH CONGENITAL JOINT DISLOCATIONS Antibodies >3 publications with CHST3 and SPONDYLOEPIPHYSEAL DYSPLASIA WITH CONGENITAL JOINT DISLOCATIONS Neoplasms Antibodies >2 publications with CHST3 and Neoplasms Drug Toxicity Antibodies >2 publications with CHST3 and Drug Toxicity Cardiovascular Abnormalities Antibodies >1 publications with CHST3 and Cardiovascular Abnormalities Heart Diseases Antibodies >1 publications with CHST3 and Heart Diseases Necrosis Antibodies >1 publications with CHST3 and Necrosis Breast Neoplasms Antibodies >1 publications with CHST3 and Breast Neoplasms Organs/Tissues associated with anti-CHST3 antibody Organ/Tissue Name Pubmed Publications Bone Antibodies >5 publications with CHST3 and Bone Vascular Antibodies >2 publications with CHST3 and Vascular Embryonic Tissue Antibodies >2 publications with CHST3 and Embryonic Tissue Umbilical Cord Antibodies >1 publications with CHST3 and Umbilical Cord Muscle Antibodies >1 publications with CHST3 and Muscle Prostate Antibodies >1 publications with CHST3 and Prostate Lung Antibodies >1 publications with CHST3 and Lung Kidney Antibodies >1 publications with CHST3 and Kidney Skin Antibodies >1 publications with CHST3 and Skin Brain Antibodies >1 publications with CHST3 and Brain TOP © 2006-24 MyBioSource.com. 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