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anti-CKBB antibody :: Goat CKBB Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS534883 anti-CKBB antibody
Unit / Price
1 mL  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CKBB, Polyclonal Antibody

 Also Known As   

CKBB antibody

 Product Synonym Names    Polyclonal CKBB; Anti-CKBB; Creatine Kinase BB Isoenzyme; CK BB; CKBB
 Product Gene Name   

anti-CKBB antibody

[Similar Products]
 Matching Pairs    Capture Antibody: CKBB (MBS534883)
Detection Antibody: CKMM (MBS535053)
Comments: Multiple lots available, varying titers
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    123280
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 Clonality    Polyclonal
 Host    Goat
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 Specificity    Human
 Form/Format    Neat serum with 0.1% NaN3.
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 Biological Significance    In the cells, the "cytosolic" creatine kinase (CK) enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are, therefore, three different isoenzymes: CK-MM, CK-BB and CK-MB. The genes for these subunits are located on different chromosomes: B on 14q32 and M on 19q13. In addition to those three cytosolic CK isoforms, there are two mitochondrial creatine kinase isoenzymes, the ubiquitous and sarcomeric form.
 Biohazard Information    This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
 Immunogen    CKBB antibody was raised in goat using purified human brain CKBB as the immunogen.
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 Preparation and Storage    Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
 Other Notes    Small volumes of anti-CKBB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CKBB antibody

   Goat polyclonal CKBB antibody
 Product Categories/Family for anti-CKBB antibody    Cardiac Markers
 Applications Tested/Suitable for anti-CKBB antibody   

User optimized

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NCBI/Uniprot data below describe general gene information for CKBB. It may not necessarily be applicable to this product.
 NCBI GI #    21536286
 NCBI GeneID    1152
 NCBI Accession #    NP_001814.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001823.4 [Other Products]
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 UniProt Secondary Accession #    Q2LE07; Q6FG40; Q9UC66; A8K236; B2R5R4 [Other Products]
 UniProt Related Accession #    P12277 [Other Products]
 Molecular Weight    42,644 Da
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 NCBI Official Full Name    creatine kinase B-type
 NCBI Official Synonym Full Names    creatine kinase, brain
 NCBI Official Symbol    CKB [Similar Products]
 NCBI Official Synonym Symbols   
BCK; B-CK; CKBB; HEL-211; HEL-S-29
[Similar Products]
 NCBI Protein Information    creatine kinase B-type
 UniProt Protein Name    Creatine kinase B-type
 UniProt Synonym Protein Names   
B-CK; Creatine kinase B chain
 UniProt Gene Name    CKB [Similar Products]
 UniProt Synonym Gene Names    CKBB [Similar Products]
 UniProt Entry Name    KCRB_HUMAN
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 NCBI Summary for CKBB    The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CKBB    CKB: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. Belongs to the ATP:guanido phosphotransferase family.

Protein type: Amino Acid Metabolism - arginine and proline; Kinase, other; EC 2.7.3.2

Chromosomal Location of Human Ortholog: 14q32

Cellular Component: mitochondrion; cytosol

Molecular Function: protein binding; creatine kinase activity; ATP binding

Biological Process: substantia nigra development; phosphorylation; cellular chloride ion homeostasis; creatine metabolic process
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 Research Articles on CKBB    1. increased serum Ckbb reflects failure of osteoclasts or suppression of osteoclasts in children with osteogenesis imperfecta during neridronate treatment
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CKBB antibodyPathways associated with anti-CKBB antibody
 Reference Product  PubMed Publications
 CKM antibody  >15 publications with CKBB and CKM
 ASB9 antibody  >2 publications with CKBB and ASB9
 LDHA antibody  >1 publications with CKBB and LDHA
 LDHB antibody  >1 publications with CKBB and LDHB
 GAMT antibody  >1 publications with CKBB and GAMT
 Products by Pathway  Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Creatine Metabolism Pathway antibodies  Creatine Metabolism Pathway Diagram
 Creatine Pathway antibodies  Creatine Pathway Diagram
 Creatine Pathway antibodies  Creatine Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Amino Acids And Derivatives Pathway antibodies  Metabolism Of Amino Acids And Derivatives Pathway Diagram
 Urea Cycle And Metabolism Of Amino Groups Pathway antibodies  Urea Cycle And Metabolism Of Amino Groups Pathway Diagram
 Creatine-phosphate Biosynthesis Pathway antibodies  Creatine-phosphate Biosynthesis Pathway Diagram
Diseases associated with anti-CKBB antibodyOrgans/Tissues associated with anti-CKBB antibody
 Disease Name  Pubmed Publications
 Brain Diseases Antibodies  >19 publications with CKBB and Brain Diseases
 Nervous System Diseases Antibodies  >14 publications with CKBB and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >10 publications with CKBB and Cardiovascular Diseases
 Heart Diseases Antibodies  >8 publications with CKBB and Heart Diseases
 Liver Diseases Antibodies  >5 publications with CKBB and Liver Diseases
 Adenocarcinoma Antibodies  >5 publications with CKBB and Adenocarcinoma
 Cognition Disorders Antibodies  >4 publications with CKBB and Cognition Disorders
 Lung Diseases Antibodies  >4 publications with CKBB and Lung Diseases
 Neoplasms, Experimental Antibodies  >4 publications with CKBB and Neoplasms, Experimental
 Hypertension Antibodies  >3 publications with CKBB and Hypertension
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >64 publications with CKBB and Brain
 Blood Antibodies  >32 publications with CKBB and Blood
 Muscle Antibodies  >18 publications with CKBB and Muscle
 Uterus Antibodies  >13 publications with CKBB and Uterus
 Heart Antibodies  >11 publications with CKBB and Heart
 Liver Antibodies  >8 publications with CKBB and Liver
 Nerve Antibodies  >7 publications with CKBB and Nerve
 Bone Antibodies  >6 publications with CKBB and Bone
 Lung Antibodies  >5 publications with CKBB and Lung
 Lymph Node Antibodies  >4 publications with CKBB and Lymph Node
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