View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Add To Compare List anti-CLDN5 antibody :: Rabbit anti-Human, Mouse CLDN5 / Claudin 5 Polyclonal Antibody Catalog # MBS242654 Unit / Price DISCONTINUEDClick here to view our similar product(s) OR click here to contact our technical support team for suitable replacement. Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name CLDN5 / Claudin 5, Polyclonal Antibody Full Product Name Rabbit Polyclonal to Mouse CLDN5 / Claudin 5 Product Synonym Names Anti-CLDN5 / Claudin 5 Antibody (C-Terminus) IHC-plus; CLDN5; BEC1; AWAL; Claudin-5; CPETRL1; TMDVCF; TMVCF; Claudin 5; Mouse CLDN5; Claudin 5 Product Gene Name anti-CLDN5 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM 602101 3D Structure ModBase 3D Structure for O00501 Clonality Polyclonal Host Rabbit Species Reactivity Human, Mouse Purity/Purification Immunoaffinity Purified Form/Format 10 mM PBS, pH 7.4, BSA, sodium azide. Concentration 0.94 mg/ml (lot specific) Target Species Mouse Immunogen Description A synthetic peptide derived from the C-terminus of mouse Claudin-5. Immunogen Type Synthetic peptide Immunogen CLDN5 / Claudin 5 antibody was raised against a synthetic peptide derived from the C-terminus of mouse Claudin-5. Antigen Modification C-Terminus Preparation and Storage Store at 2 degree C to 8 degree C degrees. Do not freeze. Other Notes Small volumes of anti-CLDN5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-CLDN5 antibody This gene is deleted in patients with velocardiofacial syndrome which is characterized by a wide spectrum of phenotypes including cleft palate, conotruncal heart defects, and facial dysmorphology. It is expressed abundantly in human adult lung, heart, and skeletal muscle. Product Categories/Family for anti-CLDN5 antibody Family: Claudin Applications Tested/Suitable for anti-CLDN5 antibody Immunohistochemistry (IHC - Paraffin), Western Blot (WB) Application Notes for anti-CLDN5 antibody IHC-P (15 ug/ml), WBUsage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti... Immunohistochemistry (IHC) of anti-CLDN5 antibody Anti-CLDN5 / Claudin 5 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml. Immunohistochemistry (IHC) of anti-CLDN5 antibody Anti-CLDN5 / Claudin 5 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml. TOP NCBI/Uniprot data below describe general gene information for CLDN5. It may not necessarily be applicable to this product. NCBI GI # 195947372 NCBI GeneID 7122 NCBI Accession # NP_003268.2 [Other Products] NCBI GenBank Nucleotide # NM_003277.3 [Other Products] UniProt Primary Accession # O00501 [Other Products] UniProt Secondary Accession # Q53XW2; Q8WUW3; B3KS11[Other Products] UniProt Related Accession # O00501[Other Products] Molecular Weight 23,147 Da TOP NCBI Official Full Name claudin-5 NCBI Official Synonym Full Names claudin 5 NCBI Official Symbol CLDN5 [Similar Products] NCBI Official Synonym Symbols AWAL; BEC1; TMVCF; CPETRL1 [Similar Products] NCBI Protein Information claudin-5; TMDVCF; transmembrane protein deleted in VCFS; transmembrane protein deleted in velocardiofacial syndrome UniProt Protein Name Claudin-5 UniProt Synonym Protein Names Transmembrane protein deleted in VCFS; TMDVCF Protein Family Claudin UniProt Gene Name CLDN5 [Similar Products] UniProt Synonym Gene Names AWAL; TMVCF; TMDVCF [Similar Products] UniProt Entry Name CLD5_HUMAN TOP NCBI Summary for CLDN5 This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Aug 2008] TOP UniProt Comments for CLDN5 Claudin-5: Plays a major role in tight junction-specific obliteration of the intercellular space. Belongs to the claudin family.Protein type: Cytoskeletal; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 22q11.21Cellular Component: tight junction; integral to membrane; plasma membrane; intercellular junctionMolecular Function: identical protein binding; structural molecule activityBiological Process: calcium-independent cell-cell adhesion Research Articles on CLDN5 1. loss of claudin 5 expression in the tumour vasculature points to a leaky vessel type TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with anti-CLDN5 antibody Reference Product PubMed Publications CLDN1 antibody >132 publications with CLDN5 and CLDN1 OCLN antibody >131 publications with CLDN5 and OCLN TJP1 antibody >130 publications with CLDN5 and TJP1 CLDN3 antibody >49 publications with CLDN5 and CLDN3 VEGFA antibody >9 publications with CLDN5 and VEGFA TJP2 antibody >7 publications with CLDN5 and TJP2 ESAM antibody >2 publications with CLDN5 and ESAM TJP3 antibody >1 publications with CLDN5 and TJP3 MPDZ antibody >1 publications with CLDN5 and MPDZ Pathways associated with anti-CLDN5 antibody Products by Pathway Pathway Diagram Cell Adhesion Molecules (CAMs) Pathway antibodies Cell Adhesion Molecules (CAMs) Pathway Diagram Cell Adhesion Molecules (CAMs) Pathway antibodies Cell Adhesion Molecules (CAMs) Pathway Diagram Cell Junction Organization Pathway antibodies Cell Junction Organization Pathway Diagram Cell-Cell Communication Pathway antibodies Cell-Cell Communication Pathway Diagram Cell-cell Junction Organization Pathway antibodies Cell-cell Junction Organization Pathway Diagram Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram Hepatitis C Pathway antibodies Hepatitis C Pathway Diagram Hepatitis C Pathway antibodies Hepatitis C Pathway Diagram Leukocyte Transendothelial Migration Pathway antibodies Leukocyte Transendothelial Migration Pathway Diagram Leukocyte Transendothelial Migration Pathway antibodies Leukocyte Transendothelial Migration Pathway Diagram Diseases associated with anti-CLDN5 antibody Disease Name Pubmed Publications Nervous System Diseases Antibodies >169 publications with CLDN5 and Nervous System Diseases Cardiovascular Diseases Antibodies >109 publications with CLDN5 and Cardiovascular Diseases Edema Antibodies >100 publications with CLDN5 and Edema Inflammation Antibodies >87 publications with CLDN5 and Inflammation Necrosis Antibodies >36 publications with CLDN5 and Necrosis Adenocarcinoma Antibodies >25 publications with CLDN5 and Adenocarcinoma Breast Neoplasms Antibodies >15 publications with CLDN5 and Breast Neoplasms Heart Diseases Antibodies >13 publications with CLDN5 and Heart Diseases Liver Diseases Antibodies >12 publications with CLDN5 and Liver Diseases Neoplasm Metastasis Antibodies >9 publications with CLDN5 and Neoplasm Metastasis Organs/Tissues associated with anti-CLDN5 antibody Organ/Tissue Name Pubmed Publications Brain Antibodies >427 publications with CLDN5 and Brain Vascular Antibodies >348 publications with CLDN5 and Vascular Nerve Antibodies >57 publications with CLDN5 and Nerve Eye Antibodies >49 publications with CLDN5 and Eye Lung Antibodies >46 publications with CLDN5 and Lung Embryonic Tissue Antibodies >39 publications with CLDN5 and Embryonic Tissue Intestine Antibodies >30 publications with CLDN5 and Intestine Muscle Antibodies >27 publications with CLDN5 and Muscle Heart Antibodies >27 publications with CLDN5 and Heart Skin Antibodies >20 publications with CLDN5 and Skin TOP © 2006-24 MyBioSource.com. All rights reserved. Privacy Policy | Terms & Conditions Our Best Sellers ADAMTS-like protein 2 (ADAMTSL2) ELISA Kit ACTC1 Antibody Alpha-Gliadin Peptide IGF BP3 Antibody CD19 Recombinant Antibody Immune Ribonucleic Acid-Immune Rna (IRNA) ELISA Kit versican (VCAN) ELISA Kit GEN1 Antibody ELISA Antibodies Secondary Antibodies Antigens Biochemicals cDNA Clones Kits Peptides Rec Proteins Protein Family Request a Quote Please fill out the form below and our representative will get back to you shortly. Catalog # MBS000000 Your E-mail (required) Ship to Country (required) United StatesAfghanistanAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBosnia and HerzegowinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCook IslandsCosta RicaCote DIvoireCroatiaCubaCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEast TimorEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrance MetropolitanFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuamGuatemalaGuineaGuinea-bissauGuyanaHaitiHeard and Mc Donald IslandsHondurasHong KongHungaryIcelandIndiaIndonesiaIran (Islamic Republic of)IraqIrelandIsraelItalyJamaicaJapanJordanKazakhstanKenyaKiribatiKorea Democratic People Republic ofKorea Republic ofKuwaitKyrgyzstanLao People Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacauMacedonia The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMarshall IslandsMartiniqueMauritaniaMauritiusMayotteMexicoMicronesia Federated States ofMoldova Republic ofMonacoMongoliaMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNetherlands AntillesNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorthern Mariana IslandsNorwayOmanPakistanPalauPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalPuerto RicoQatarReunionRomaniaRussian FederationRwandaSaint Kitts and NevisSaint LuciaSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSeychellesSierra LeoneSingaporeSlovakia (Slovak Republic)SloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSpainSri LankaSt. HelenaSt. Pierre and MiquelonSudanSurinameSvalbard and Jan Mayen IslandsSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania United Republic ofThailandTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUnited States Minor Outlying IslandsUruguayUzbekistanVanuatuVatican City State (Holy See)VenezuelaViet NamVirgin Islands (British)Virgin Islands (U.S.)Wallis and Futuna IslandsWestern SaharaYemenYugoslaviaZaireZambiaZimbabwe Postal/Zip Code (required) Your Name Your Telephone Your Inquiries, Comments or Full Shipping Address (required) Contact Us Please fill out the form below and our representative will get back to you shortly. Inquiry for # MBS000000 Your Name Your Telephone Your E-mail (required) Your Inquiries or Comments