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anti-CNGA4 antibody :: Rabbit anti-Human CNGA4 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7002192 anti-CNGA4 antibody
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CNGA4, Polyclonal Antibody

 Also Known As   

CNGA4 Antibody; Biotin conjugated

 Product Synonym Names    Cyclic nucleotide-gated cation channel alpha-4; Cyclic nucleotide-gated channel alpha-4; CNG channel alpha-4; CNG-4; CNG4; CNGA4
 Product Gene Name   

anti-CNGA4 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    609472
 3D Structure    ModBase 3D Structure for Q8IV77
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    >95%,Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant human Cyclic nucleotide-gated cation channel alpha-4 protein
 Conjugation    Biotin
 Storage Buffer    Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-167508
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CNGA4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CNGA4 antibody

   Second messenger, cAMP, causes the opening of cation-selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.
 Applications Tested/Suitable for anti-CNGA4 antibody   

ELISA (EIA)

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NCBI/Uniprot data below describe general gene information for CNGA4. It may not necessarily be applicable to this product.
 NCBI GI #    82617546
 NCBI GeneID    1262
 NCBI Accession #    NP_001032406.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001037329.3 [Other Products]
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 UniProt Primary Accession #    Q8IV77 [Other Products]
 UniProt Related Accession #    Q8IV77 [Other Products]
 Molecular Weight    47,743 Da
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 NCBI Official Full Name    cyclic nucleotide-gated cation channel alpha-4
 NCBI Official Synonym Full Names    cyclic nucleotide gated channel alpha 4
 NCBI Official Symbol    CNGA4 [Similar Products]
 NCBI Official Synonym Symbols   
CNG4; CNG5; CNCA2; CNG-4; CNGB2; OCNC2; OCNCb; OCNCBETA
[Similar Products]
 NCBI Protein Information    cyclic nucleotide-gated cation channel alpha-4
 UniProt Protein Name    Cyclic nucleotide-gated cation channel alpha-4
 UniProt Synonym Protein Names   
Cyclic nucleotide-gated channel alpha-4; CNG channel alpha-4; CNG-4; CNG4
 Protein Family    Cyclic nucleotide-gated cation channel
 UniProt Gene Name    CNGA4 [Similar Products]
 UniProt Synonym Gene Names    CNG channel alpha-4; CNG-4; CNG4 [Similar Products]
 UniProt Entry Name    CNGA4_HUMAN
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 NCBI Summary for CNGA4    CNGA4 is a modulatory subunit of vertebrate cyclic nucleotide-gated membrane channels that transduce odorant signals (Munger et al., 2001 [PubMed 11739959]).[supplied by OMIM, Mar 2008]
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 UniProt Comments for CNGA4    CNGA4: Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection. Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA4 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: Golgi membrane; intracellular cyclic nucleotide activated cation channel complex; perikaryon

Molecular Function: cAMP binding; cGMP binding; intracellular cAMP activated cation channel activity; intracellular cGMP activated cation channel activity; voltage-gated potassium channel activity

Biological Process: organelle organization and biogenesis; protein heterotetramerization; regulation of membrane potential; response to stimulus; sensory perception of smell
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CNGA4 antibodyOrgans/Tissues associated with anti-CNGA4 antibody
 Products by Pathway  Pathway Diagram
 Assembly Of The Primary Cilium Pathway antibodies  Assembly Of The Primary Cilium Pathway Diagram
 Cargo Trafficking To The Periciliary Membrane Pathway antibodies  Cargo Trafficking To The Periciliary Membrane Pathway Diagram
 Olfactory Transduction Pathway antibodies  Olfactory Transduction Pathway Diagram
 Olfactory Transduction Pathway antibodies  Olfactory Transduction Pathway Diagram
 Organelle Biogenesis And Maintenance Pathway antibodies  Organelle Biogenesis And Maintenance Pathway Diagram
 VxPx Cargo-targeting To Cilium Pathway antibodies  VxPx Cargo-targeting To Cilium Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram
 CAMP Signaling Pathway antibodies  CAMP Signaling Pathway Diagram
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with CNGA4 and Brain
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