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anti-CNN2 antibody :: Rabbit anti-Human, Mouse CNN2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7051100
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CNN2, Polyclonal Antibody

★Popular Item★
 Also Known As   

CNN2 Antibody

 Product Synonym Names    Calponin-2; Calponin H2; smooth muscle; Neutral calponin; CNN2
 Product Gene Name   

anti-CNN2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    D83735 mRNA
 3D Structure    ModBase 3D Structure for Q99439
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse
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 Purity/Purification    >95%, Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant Human Calponin-2 protein (2-309AA)
 Preservative    0.03% Proclin 300
 Constituents    50% Glycerol, 0.01M PBS, PH 7.4
 Conjugation    Non-conjugated
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-16607 / sc-16608
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CNN2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CNN2 antibody

   Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
 Applications Tested/Suitable for anti-CNN2 antibody   

ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)

 Application Notes for anti-CNN2 antibody    WB: 1: 2000-1: 10000
IF: 1: 50-1: 200
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 Western Blot (WB) of anti-CNN2 antibody    Western Blot
Positive WB detected in:Hela whole cell lysate,Mouse liver tissue,Mouse lung tissue,Mouse kidney tissue,Mouse brain tissue,Mouse skeletal muscle tissue
All lanes: CNN2 antibody at 2.5ug/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 34,30 kDa
Observed band size: 34 kDa

anti-CNN2 antibody Western Blot (WB) (WB) image
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 Immunofluorescence (IF) of anti-CNN2 antibody    Immunofluorescent analysis of HepG2 cells using MBS7051100 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
anti-CNN2 antibody Immunofluorescence (IF) image
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NCBI/Uniprot data below describe general gene information for CNN2. It may not necessarily be applicable to this product.
 NCBI GI #    746576343
 NCBI GeneID    1265
 NCBI Accession #    NP_001290428.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001303499.1 [Other Products]
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 UniProt Primary Accession #    Q99439 [Other Products]
 UniProt Secondary Accession #    Q92578; A5D8U8; A6NFI4; D6W5X9 [Other Products]
 UniProt Related Accession #    Q99439 [Other Products]
 Molecular Weight    29,500 Da
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 NCBI Official Full Name    calponin-2 isoform c
 NCBI Official Synonym Full Names    calponin 2
 NCBI Official Symbol    CNN2 [Similar Products]
 NCBI Protein Information    calponin-2
 UniProt Protein Name    Calponin-2
 UniProt Synonym Protein Names   
Calponin H2, smooth muscle; Neutral calponin
 Protein Family    Calponin
 UniProt Gene Name    CNN2 [Similar Products]
 UniProt Entry Name    CNN2_HUMAN
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 NCBI Summary for CNN2    The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
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 UniProt Comments for CNN2    calponin 2: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Belongs to the calponin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Actin-binding; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: cell-cell adherens junction; cytoskeleton; focal adhesion; intercellular junction; membrane; stress fiber

Biological Process: cytoskeleton organization and biogenesis; regulation of actin filament-based process
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 Research Articles on CNN2    1. High Calponin-h2 serum levels are associated with breast cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CNN2 antibodyPathways associated with anti-CNN2 antibody
 Reference Product  PubMed Publications
 ACTB antibody  >1 publications with CNN2 and ACTB
 Products by Pathway  Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Myometrial Relaxation And Contraction Pathways antibodies  Myometrial Relaxation And Contraction Pathways Diagram
 Neutrophil Degranulation Pathway antibodies  Neutrophil Degranulation Pathway Diagram
Diseases associated with anti-CNN2 antibodyOrgans/Tissues associated with anti-CNN2 antibody
 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >1 publications with CNN2 and Cardiovascular Diseases
 Edema Antibodies  >1 publications with CNN2 and Edema
 Neoplasms, Experimental Antibodies  >1 publications with CNN2 and Neoplasms, Experimental
 Disease Models, Animal Antibodies  >1 publications with CNN2 and Disease Models, Animal
 Inflammation Antibodies  >1 publications with CNN2 and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >4 publications with CNN2 and Blood
 Bone Antibodies  >3 publications with CNN2 and Bone
 Muscle Antibodies  >2 publications with CNN2 and Muscle
 Vascular Antibodies  >2 publications with CNN2 and Vascular
 Skin Antibodies  >2 publications with CNN2 and Skin
 Bone Marrow Antibodies  >1 publications with CNN2 and Bone Marrow
 Connective Tissue Antibodies  >1 publications with CNN2 and Connective Tissue
 Prostate Antibodies  >1 publications with CNN2 and Prostate
 Embryonic Tissue Antibodies  >1 publications with CNN2 and Embryonic Tissue
 Brain Antibodies  >1 publications with CNN2 and Brain
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