View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List anti-COX4I1 antibody :: Rabbit anti-Human COX4I1 Polyclonal Antibody Catalog # MBS2543113 Unit / Price 0.02 mL / $150 +1 FREE 8GB USB 0.06 mL / $190 +1 FREE 8GB USB 0.12 mL / $270 +1 FREE 8GB USB 0.2 mL / $415 +1 FREE 8GB USB Previous Next Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name COX4I1, Polyclonal Antibody Popular Item Full Product Name COX4I1 Polyclonal Antibody Product Synonym Names COX4; COXIV; COX4-1 Product Gene Name anti-COX4I1 antibody[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP OMIM M21575 mRNA Clonality Polyclonal Isotype IgG Host Rabbit Species Reactivity Human Purity/Purification Antigen Affinity Purification Concentration 1.3mg/ml (lot specific) Immunogen Synthetic peptide of human COX4I1 Buffer PBS with 0.05% sodium azide, 50% glycerol, pH7.3 Santa Cruz Alternative Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-376731 Preparation and Storage Store at -20 degree C. Avoid freeze/thaw cycles. ISO Certification Manufactured in an ISO 9001:2015 Certified Laboratory. Other Notes Small volumes of anti-COX4I1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. TOP Related Product Information for anti-COX4I1 antibody Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Applications Tested/Suitable for anti-COX4I1 antibody ELISA (EIA), Immunohistochemistry (IHC) Application Notes for anti-COX4I1 antibody ELISA: 1:2000-5000IHC: 1:20-100 Immunohistochemistry (IHC) of anti-COX4I1 antibody Immunohistochemistry of paraffin-embedded Human tonsil tissue using COX4I1 Polyclonal Antibody at dilution 1:20 Immunohistochemistry (IHC) of anti-COX4I1 antibody Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using COX4I1 Polyclonal Antibody at dilution 1:20 TOP NCBI/Uniprot data below describe general gene information for COX4I1. It may not necessarily be applicable to this product. NCBI GI # 28839782 NCBI GeneID 1327 UniProt Secondary Accession # Q6P666; B2R4J2; D3DUM7[Other Products] UniProt Related Accession # P13073[Other Products] Molecular Weight 19,577 Da TOP NCBI Official Full Name COX4I1 protein NCBI Official Synonym Full Names cytochrome c oxidase subunit 4I1 NCBI Official Symbol COX4I1 [Similar Products] NCBI Official Synonym Symbols COX4; COXIV; COX4-1; COXIV-1; COX IV-1 [Similar Products] NCBI Protein Information cytochrome c oxidase subunit 4 isoform 1, mitochondrial UniProt Protein Name Cytochrome c oxidase subunit 4 isoform 1, mitochondrial UniProt Synonym Protein Names Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1 Protein Family Cytochrome c oxidase UniProt Gene Name COX4I1 [Similar Products] UniProt Synonym Gene Names COX4; COX IV-1 [Similar Products] UniProt Entry Name COX41_HUMAN TOP NCBI Summary for COX4I1 Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. Pseudogenes related to this gene are located on chromosomes 13 and 14. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] TOP UniProt Comments for COX4I1 COX4I1: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Ubiquitous. Belongs to the cytochrome c oxidase IV family.Protein type: EC 1.9.3.1; Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Mitochondrial; OxidoreductaseChromosomal Location of Human Ortholog: 16q24.1Cellular Component: membrane; mitochondrial inner membrane; mitochondrial respiratory chain complex IV; mitochondrion; nucleusMolecular Function: protein bindingBiological Process: generation of precursor metabolites and energy; mitochondrial electron transport, cytochrome c to oxygen Research Articles on COX4I1 1. We provide evidence that COX4-1 controls BMI1 expression via a redox mechanism TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. 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TOP Products associated with anti-COX4I1 antibody Reference Product PubMed Publications COX5B antibody >2 publications with COX4I1 and COX5B COX5A antibody >2 publications with COX4I1 and COX5A MT-CO2 antibody >2 publications with COX4I1 and MT-CO2 COX7C antibody >1 publications with COX4I1 and COX7C COX6B1 antibody >1 publications with COX4I1 and COX6B1 Pathways associated with anti-COX4I1 antibody Products by Pathway Pathway Diagram Alzheimer's Disease Pathway antibodies Alzheimer's Disease Pathway Diagram Alzheimer's Disease Pathway antibodies Alzheimer's Disease Pathway Diagram Cardiac Muscle Contraction Pathway antibodies Cardiac Muscle Contraction Pathway Diagram Cardiac Muscle Contraction Pathway antibodies Cardiac Muscle Contraction Pathway Diagram Cytochrome C Oxidase Pathway antibodies Cytochrome C Oxidase Pathway Diagram Cytochrome C Oxidase Pathway antibodies Cytochrome C Oxidase Pathway Diagram Electron Transport Chain Pathway antibodies Electron Transport Chain Pathway Diagram Gene Expression Pathway antibodies Gene Expression Pathway Diagram Generic Transcription Pathway antibodies Generic Transcription Pathway Diagram Huntington's Disease Pathway antibodies Huntington's Disease Pathway Diagram Diseases associated with anti-COX4I1 antibody Disease Name Pubmed Publications Fatty Liver Antibodies >5 publications with COX4I1 and Fatty Liver Disease Models, Animal Antibodies >3 publications with COX4I1 and Disease Models, Animal Death Antibodies >2 publications with COX4I1 and Death Weight Loss Antibodies >2 publications with COX4I1 and Weight Loss Cardiovascular Diseases Antibodies >1 publications with COX4I1 and Cardiovascular Diseases Atrophy Antibodies >1 publications with COX4I1 and Atrophy Heart Diseases Antibodies >1 publications with COX4I1 and Heart Diseases Fibrosis Antibodies >1 publications with COX4I1 and Fibrosis Liver Diseases Antibodies >1 publications with COX4I1 and Liver Diseases Kidney Diseases Antibodies >1 publications with COX4I1 and Kidney Diseases Organs/Tissues associated with anti-COX4I1 antibody Organ/Tissue Name Pubmed Publications Muscle Antibodies >11 publications with COX4I1 and Muscle Liver Antibodies >8 publications with COX4I1 and Liver Blood Antibodies >8 publications with COX4I1 and Blood Adipose Tissue Antibodies >7 publications with COX4I1 and Adipose Tissue Brain Antibodies >5 publications with COX4I1 and Brain Kidney Antibodies >2 publications with COX4I1 and Kidney Heart Antibodies >2 publications with COX4I1 and Heart Connective Tissue Antibodies >2 publications with COX4I1 and Connective Tissue Skin Antibodies >1 publications with COX4I1 and Skin Embryonic Tissue Antibodies >1 publications with COX4I1 and Embryonic Tissue TOP