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anti-COX5B antibody :: Rabbit COX5B Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS859591
Testing Data
Unit / Price
0.1 mg  /  $215 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

COX5B, Polyclonal Antibody

 Also Known As   

COX5B Antibody

 Product Synonym Names    Cytochrome c oxidase polypeptide Vb; Cytochrome c oxidase subunit 5B; mitochondrial precursor; EC 1.9.3.1
 Product Gene Name   

anti-COX5B antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    123866
 3D Structure    ModBase 3D Structure for P10606
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    COX5B antibody detects endogenous levels of total COX5B protein.
 Purity/Purification    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
 Form/Format    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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 Reactivity Note    Human (Identities = 100%, Positives = 100%); Mouse (Identities = 100%, Positives = 100%); Rat (Identities = 100%, Positives = 100%)
 Immunogen    The antiserum was produced against synthesized peptide derived from internal of human COX5B.
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 Preparation and Storage    Store at -20 degree C for 1 year
 Other Notes    Small volumes of anti-COX5B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-COX5B antibody    Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells; Autophagy antibody
 Applications Tested/Suitable for anti-COX5B antibody   

Western Blot (WB), ELISA (EIA)

 Application Notes for anti-COX5B antibody    IHC: 1:50~1:100, ELISA: 1:20000
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 Testing Data of anti-COX5B antibody    Peptide - +
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using COX5B antibody.
anti-COX5B antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for COX5B. It may not necessarily be applicable to this product.
 NCBI GI #    17017988
 NCBI GeneID    1329
 NCBI Accession #    NP_001853.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001862.2 [Other Products]
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 UniProt Primary Accession #    P10606 [Other Products]
 UniProt Secondary Accession #    Q53YB7; Q96J18; Q99610 [Other Products]
 UniProt Related Accession #    P10606 [Other Products]
 Molecular Weight    13,696 Da
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 NCBI Official Full Name    cytochrome c oxidase subunit 5B, mitochondrial
 NCBI Official Synonym Full Names    cytochrome c oxidase subunit Vb
 NCBI Official Symbol    COX5B [Similar Products]
 NCBI Official Synonym Symbols   
COXVB
[Similar Products]
 NCBI Protein Information    cytochrome c oxidase subunit 5B, mitochondrial; cytochrome c oxidase polypeptide VB, mitochondrial
 UniProt Protein Name    Cytochrome c oxidase subunit 5B, mitochondrial
 UniProt Synonym Protein Names   
Cytochrome c oxidase polypeptide Vb
 Protein Family    Cytochrome c oxidase polypeptide
 UniProt Gene Name    COX5B [Similar Products]
 UniProt Entry Name    COX5B_HUMAN
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 NCBI Summary for COX5B    Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain enzyme. [provided by RefSeq, Jul 2008]
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 UniProt Comments for COX5B    COX5B: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase subunit 5B family.

Protein type: Mitochondrial; Energy Metabolism - oxidative phosphorylation; Oxidoreductase; EC 1.9.3.1

Chromosomal Location of Human Ortholog: 2q11.2

Cellular Component: mitochondrion; mitochondrial inner membrane

Molecular Function: cytochrome-c oxidase activity; metal ion binding

Biological Process: cellular metabolic process; respiratory gaseous exchange; transmembrane transport
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Product References and Citations for anti-COX5B antibody

   Lomax M.I., Genomics 10:1-9(1991).
Bachman N.J., Arch. Biochem. Biophys. 333:152-162(1996).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
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 Research Articles on COX5B    1. Transfected the A549 cells with COX Vb small interfering or shRNA and observed a significant reduction of their COX activity, oxygen consumption, ATP and ability to grow in soft agar and as poorly differentiated tumors in athymic mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-COX5B antibodyPathways associated with anti-COX5B antibody
 Reference Product  PubMed Publications
 COX5A antibody  >22 publications with COX5B and COX5A
 CYC1 antibody  >4 publications with COX5B and CYC1
 COX7C antibody  >2 publications with COX5B and COX7C
 MT-CO2 antibody  >2 publications with COX5B and MT-CO2
 COX6B1 antibody  >1 publications with COX5B and COX6B1
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cardiac Muscle Contraction Pathway antibodies  Cardiac Muscle Contraction Pathway Diagram
 Cytochrome C Oxidase Pathway antibodies  Cytochrome C Oxidase Pathway Diagram
 Cytochrome C Oxidase Pathway antibodies  Cytochrome C Oxidase Pathway Diagram
 Electron Transport Chain Pathway antibodies  Electron Transport Chain Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
Diseases associated with anti-COX5B antibodyOrgans/Tissues associated with anti-COX5B antibody
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >2 publications with COX5B and Heart Diseases
 Disease Models, Animal Antibodies  >2 publications with COX5B and Disease Models, Animal
 Cardiovascular Diseases Antibodies  >2 publications with COX5B and Cardiovascular Diseases
 Death Antibodies  >1 publications with COX5B and Death
 Fibrosis Antibodies  >1 publications with COX5B and Fibrosis
 Hypertrophy Antibodies  >1 publications with COX5B and Hypertrophy
 Breast Neoplasms Antibodies  >1 publications with COX5B and Breast Neoplasms
 Liver Neoplasms Antibodies  >1 publications with COX5B and Liver Neoplasms
 Adenocarcinoma Antibodies  >1 publications with COX5B and Adenocarcinoma
 Atrophy Antibodies  >1 publications with COX5B and Atrophy
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >8 publications with COX5B and Muscle
 Brain Antibodies  >5 publications with COX5B and Brain
 Vascular Antibodies  >4 publications with COX5B and Vascular
 Blood Antibodies  >4 publications with COX5B and Blood
 Heart Antibodies  >2 publications with COX5B and Heart
 Kidney Antibodies  >2 publications with COX5B and Kidney
 Liver Antibodies  >2 publications with COX5B and Liver
 Skin Antibodies  >1 publications with COX5B and Skin
 Thyroid Antibodies  >1 publications with COX5B and Thyroid
 Intestine Antibodies  >1 publications with COX5B and Intestine
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