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anti-CPEB1 antibody :: Goat CPEB1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS420722
Western Blot (WB)
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CPEB1, Polyclonal Antibody

 Also Known As   

Goat anti-CPEB1 Antibody

 Product Synonym Names    CPEB1; CPEB; FLJ13203; cytoplasmic polyadenylation element binding protein 1; CEBP; CPE-BP1; MGC34136; MGC60106; CPE-binding protein 1; CPEB1 antibody; CPEB antibody; FLJ13203 antibody; cytoplasmic polyadenylation element binding protein 1 antibody; CEBP antibody; CPE-BP1 antibody; MGC34136 antibody; MGC60106 antibody; CPE-binding protein 1 antibody
 Product Gene Name   

anti-CPEB1 antibody

[Similar Products]
 Antibody/Peptide Pairs    CPEB1 peptide (MBS425647) is used for blocking the activity of CPEB1 antibody (MBS420722)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    PLMRNQKNRD SS
 OMIM    607342
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human, Cow
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-PLMRNQKNRDSS, from the C Terminus of the protein sequence according to NP_085097.3; NP_001073001.1; NP_001073002.1; NP_001073003.1.
 Epitope    C Terminus
 Note    This antibody is expected to recognise alle reported isoforms. Variants (NP_001073002.1; NP_001073003.1) encode the same isoform.
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-CPEB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CPEB1 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-CPEB1 antibody    Peptide ELISA: Antibody detection limit dilution 1: 128000.
Western Blot: Approx 65-70kDa band observed in human brain lysates (predicted MW of 65kDa according to NP_085097). Recommended for use at 0.5-2ug/ml. Please note this band was always accompanied by a slightly stonger band at approx 48kDa and further both bands could be blocked by incubation with the immunising peptide.
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 Western Blot (WB) of anti-CPEB1 antibody    Staining (0.5ug/ml) of human brain lysate (RIPA buffer, 35ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
anti-CPEB1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CPEB1. It may not necessarily be applicable to this product.
 NCBI GI #    119395725
 NCBI GeneID    64506
 NCBI Accession #    NP_085097.3 [Other Products]
 NCBI Related Accession #    NP_001073001.1; NP_001073002.1; NP_001073003.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_030594.4 [Other Products]
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 UniProt Secondary Accession #    Q86W46; Q8IV41; Q9BZB7; Q9H8V5; B7Z6C6 [Other Products]
 UniProt Related Accession #    Q9BZB8 [Other Products]
 Molecular Weight    53,635 Da
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 NCBI Official Full Name    cytoplasmic polyadenylation element-binding protein 1 isoform 1
 NCBI Official Synonym Full Names    cytoplasmic polyadenylation element binding protein 1
 NCBI Official Symbol    CPEB1 [Similar Products]
 NCBI Official Synonym Symbols   
CPEB; CPEB-1; h-CPEB; CPE-BP1; hCPEB-1
[Similar Products]
 NCBI Protein Information    cytoplasmic polyadenylation element-binding protein 1
 UniProt Protein Name    Cytoplasmic polyadenylation element-binding protein 1
 UniProt Gene Name    CPEB1 [Similar Products]
 UniProt Synonym Gene Names    CPEB; CPE-BP1; CPE-binding protein 1; h-CPEB; hCPEB-1 [Similar Products]
 UniProt Entry Name    CPEB1_HUMAN
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 NCBI Summary for CPEB1    This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
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 UniProt Comments for CPEB1    CPEB: cytoplasmic polyadenylation element binding protein 1. Binds to the protein CPE and drives its polyadenylation. Activated by the protein kinase AurA. Insulin and progesterone stimulate AurA-catalyzed phosphorylation of CPEB in oocytes. Neuronal CPEB regulates local protein synthesis and stabilizes synapse-specific long-term facilitation in aplysia.

Protein type: Translation; RNA-binding

Chromosomal Location of Human Ortholog: 15q25.2

Cellular Component: cell junction; cell soma; centrosome; cytoplasm; dendrite; growth cone; neuron projection; nucleoplasm; nucleus; perinuclear region of cytoplasm; postsynaptic density; postsynaptic membrane; synapse

Molecular Function: metal ion binding; mRNA 3'-UTR binding; nucleotide binding; ribosome binding; translation factor activity, nucleic acid binding; translation repressor activity, nucleic acid binding

Biological Process: cellular response to insulin stimulus; mRNA processing; mRNA transport; negative regulation of cell proliferation; positive regulation of cell migration; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of translation; translation
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 Research Articles on CPEB1    1. Results suggest that CPEB1-mediated translational control is essential for the differentiation of GSCs.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CPEB1 antibodyPathways associated with anti-CPEB1 antibody
 Reference Product  PubMed Publications
 PARN antibody  >6 publications with CPEB1 and PARN
 PUM2 antibody  >5 publications with CPEB1 and PUM2
 PAPD4 antibody  >4 publications with CPEB1 and PAPD4
 AURKA antibody  >2 publications with CPEB1 and AURKA
 EIF4E1B antibody  >1 publications with CPEB1 and EIF4E1B
 BICC1 antibody  >1 publications with CPEB1 and BICC1
 NGDN antibody  >1 publications with CPEB1 and NGDN
 Products by Pathway  Pathway Diagram
 Aurora A Signaling Pathway antibodies  Aurora A Signaling Pathway Diagram
 Dorso-ventral Axis Formation Pathway antibodies  Dorso-ventral Axis Formation Pathway Diagram
 Dorso-ventral Axis Formation Pathway antibodies  Dorso-ventral Axis Formation Pathway Diagram
 Oocyte Meiosis Pathway antibodies  Oocyte Meiosis Pathway Diagram
 Oocyte Meiosis Pathway antibodies  Oocyte Meiosis Pathway Diagram
 Progesterone-mediated Oocyte Maturation Pathway antibodies  Progesterone-mediated Oocyte Maturation Pathway Diagram
 Progesterone-mediated Oocyte Maturation Pathway antibodies  Progesterone-mediated Oocyte Maturation Pathway Diagram
Diseases associated with anti-CPEB1 antibodyOrgans/Tissues associated with anti-CPEB1 antibody
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >12 publications with CPEB1 and Nervous System Diseases
 Congenital Abnormalities Antibodies  >4 publications with CPEB1 and Congenital Abnormalities
 Disease Models, Animal Antibodies  >3 publications with CPEB1 and Disease Models, Animal
 Abnormalities, Multiple Antibodies  >3 publications with CPEB1 and Abnormalities, Multiple
 Lung Neoplasms Antibodies  >2 publications with CPEB1 and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >2 publications with CPEB1 and Neoplasms, Experimental
 Cardiovascular Diseases Antibodies  >2 publications with CPEB1 and Cardiovascular Diseases
 Breast Neoplasms Antibodies  >1 publications with CPEB1 and Breast Neoplasms
 Liver Diseases Antibodies  >1 publications with CPEB1 and Liver Diseases
 Kidney Diseases Antibodies  >1 publications with CPEB1 and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >5 publications with CPEB1 and Ovary
 Testis Antibodies  >4 publications with CPEB1 and Testis
 Eye Antibodies  >2 publications with CPEB1 and Eye
 Mammary Gland Antibodies  >1 publications with CPEB1 and Mammary Gland
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