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anti-CREB1 antibody :: Rabbit CREB1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2522508
Immunohistochemistry (IHC)
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CREB1, Polyclonal Antibody

★Popular Item★
 Also Known As   

CREB1 Polyclonal Antibody

 Product Synonym Names    CREB
 Product Gene Name   

anti-CREB1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 3D Structure    ModBase 3D Structure for Q53X93
 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen affinity purification
 Concentration    0.6mg/mL (lot specific)
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 Immunogen    Recombinant protein of human CREB1
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CREB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CREB1 antibody

   This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
 Product Categories/Family for anti-CREB1 antibody    Cancer; Epigenetics; Neuroscience
 Applications Tested/Suitable for anti-CREB1 antibody   

ELISA (EIA), Immunohistochemistry (IHC)

 Application Notes for anti-CREB1 antibody    IHC: 1:15-1:50
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 Immunohistochemistry (IHC) of anti-CREB1 antibody    Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CREB1 Polyclonal Antibody at dilution 1:15
anti-CREB1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CREB1. It may not necessarily be applicable to this product.
 NCBI GI #    47115171
 NCBI GeneID    1385
 NCBI Accession #    CAG28545.1 [Other Products]
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 UniProt Primary Accession #    Q53X93 [Other Products]
 UniProt Related Accession #    P16220 [Other Products]
 Molecular Weight    35,136 Da
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 NCBI Official Full Name    CREB1, partial
 NCBI Official Synonym Full Names    cAMP responsive element binding protein 1
 NCBI Official Symbol    CREB1 [Similar Products]
 NCBI Official Synonym Symbols   
CREB
[Similar Products]
 NCBI Protein Information    cyclic AMP-responsive element-binding protein 1; CREB-1; active transcription factor CREB; cAMP-response element-binding protein-1; cAMP-responsive element-binding protein 1; transactivator protein
 UniProt Protein Name    CREB1 protein
 UniProt Synonym Protein Names   
CREB1 protein
 Protein Family    Cyclic AMP-responsive element-binding protein
 UniProt Gene Name    CREB1 [Similar Products]
 UniProt Entry Name    Q53X93_HUMAN
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 NCBI Summary for CREB1    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CREB1    CREB: a transcription factor of the leucine zipper family of DNA binding proteins. Binds as a homodimer to the cAMP-responsive element (CRE). Phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Two splice-variant isoforms have been described.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 2q34

Cellular Component: nucleoplasm; nucleus

Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; enzyme binding; transcription cofactor activity; transcription factor activity

Biological Process: lactation; circadian rhythm; transcription from RNA polymerase II promoter; axon guidance; response to glucagon stimulus; nerve growth factor receptor signaling pathway; viral reproduction; positive regulation of osteoclast differentiation; positive regulation of transcription, DNA-dependent; stress-activated MAPK cascade; toll-like receptor 3 signaling pathway; positive regulation of multicellular organism growth; signal transduction; protein amino acid phosphorylation; toll-like receptor 10 signaling pathway; response to organic substance; toll-like receptor 5 signaling pathway; synaptic transmission; toll-like receptor 4 signaling pathway; response to drug; epidermal growth factor receptor signaling pathway; mitochondrion organization and biogenesis; Notch signaling pathway; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; protein stabilization; secretory granule organization and biogenesis; organelle organization and biogenesis; MyD88-independent toll-like receptor signaling pathway; positive regulation of hormone secretion; positive regulation of lipid biosynthetic process; memory; toll-like receptor 2 signaling pathway; MyD88-dependent toll-like receptor signaling pathway; pituitary gland development; phospholipase C activation; toll-like receptor signaling pathway; positive regulation of fat cell differentiation; innate immune response; positive regulation of transcription from RNA polymerase II promoter; toll-like receptor 9 signaling pathway; regulation of cell size

Disease: Histiocytoma, Angiomatoid Fibrous
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 Research Articles on CREB1    1. Activation of CREB overexpressing neurons impaired consolidation of cocaine memory.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CREB1 antibodyDiseases associated with anti-CREB1 antibody
 Products by Pathway  Pathway Diagram
 AKT Phosphorylates Targets In The Nucleus Pathway antibodies  AKT Phosphorylates Targets In The Nucleus Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 AMPK Signaling Pathway antibodies  AMPK Signaling Pathway Diagram
 ATF-2 Transcription Factor Network Pathway antibodies  ATF-2 Transcription Factor Network Pathway Diagram
 ATM Signaling Pathway antibodies  ATM Signaling Pathway Diagram
 Activated TLR4 Signalling Pathway antibodies  Activated TLR4 Signalling Pathway Diagram
 Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway antibodies  Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Adrenergic Signaling In Cardiomyocytes Pathway antibodies  Adrenergic Signaling In Cardiomyocytes Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >110 publications with CREB1 and Nervous System Diseases
 Inflammation Antibodies  >67 publications with CREB1 and Inflammation
 Necrosis Antibodies  >45 publications with CREB1 and Necrosis
 Depressive Disorder Antibodies  >43 publications with CREB1 and Depressive Disorder
 Memory Disorders Antibodies  >42 publications with CREB1 and Memory Disorders
 Neurobehavioral Manifestations Antibodies  >37 publications with CREB1 and Neurobehavioral Manifestations
 Learning Disorders Antibodies  >31 publications with CREB1 and Learning Disorders
 Lung Neoplasms Antibodies  >27 publications with CREB1 and Lung Neoplasms
 Atherosclerosis Antibodies  >21 publications with CREB1 and Atherosclerosis
 Liver Diseases Antibodies  >18 publications with CREB1 and Liver Diseases
Organs/Tissues associated with anti-CREB1 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >297 publications with CREB1 and Brain
 Blood Antibodies  >147 publications with CREB1 and Blood
 Muscle Antibodies  >68 publications with CREB1 and Muscle
 Lung Antibodies  >64 publications with CREB1 and Lung
 Bone Antibodies  >63 publications with CREB1 and Bone
 Liver Antibodies  >60 publications with CREB1 and Liver
 Vascular Antibodies  >59 publications with CREB1 and Vascular
 Heart Antibodies  >35 publications with CREB1 and Heart
 Kidney Antibodies  >35 publications with CREB1 and Kidney
 Skin Antibodies  >35 publications with CREB1 and Skin
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