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anti-CRELD2 antibody :: Rabbit anti-Human CRELD2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2516656
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CRELD2, Polyclonal Antibody

★Popular Item★
 Also Known As   

CRELD2 Polyclonal Antibody

 Product Gene Name   

anti-CRELD2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 MBS2516656 Technical Datasheet    Technical Datasheet PDF
 OMIM    607171
 3D Structure    ModBase 3D Structure for Q6UXH1
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Affinity purification
 Concentration    0.3mg/mL (lot specific)
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 Immunogen    Recombinant protein of human CRELD2
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
 Calculated MW    38 kDa
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 Preparation and Storage    Store at -20°C. Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CRELD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CRELD2 antibody

   CRELD2 (cysteine-rich with EGF-like domains 2) is a 353 amino acid protein that is ubiquitously expressed and contains two FU domains and two EGF-like domains. Localized to the endoplasmic reticulum and secreted into the cell, CRELD2 interacts with AChRċ4, possibly regulating its transport. Human CRELD2 shares 69% amino acid identity with its mouse counterpart, suggesting a conserved role between species. Multiple isoforms of CRELD2 exist due to alternative splicing events. The gene encoding CRELD2 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome.
 Applications Tested/Suitable for anti-CRELD2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-CRELD2 antibody    WB: 1:500-1:2000
IHC: 1:50-1:200
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 Western Blot (WB) of anti-CRELD2 antibody    Western Blot analysis of Human fetal liver tissue using CRELD2 Polyclonal Antibody at dilution of 1:421
anti-CRELD2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CRELD2 antibody    Immunohistochemistry of paraffin-embedded Human cervical cancer using CRELD2 Polyclonal Antibody at dilution of 1:40
anti-CRELD2 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CRELD2 antibody    Immunohistochemistry of paraffin-embedded Human thyroid cancer using CRELD2 Polyclonal Antibody at dilution of 1:40
anti-CRELD2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CRELD2. It may not necessarily be applicable to this product.
 NCBI GI #    546231991
 NCBI GeneID    79174
 NCBI Accession #    BC002894 [Other Products]
 NCBI GenBank Nucleotide #    NM_001284318.1 [Other Products]
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 UniProt Primary Accession #    Q6UXH1 [Other Products]
 UniProt Secondary Accession #    Q4W0V0; Q86UC0; Q9BU47; A5GZA2; A5GZA3; A5GZA4; A5GZA5; A5GZA6 [Other Products]
 UniProt Related Accession #    Q6UXH1 [Other Products]
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 NCBI Official Full Name    cysteine-rich with EGF-like domain protein 2 isoform d
 NCBI Official Synonym Full Names    cysteine-rich with EGF-like domains 2
 NCBI Official Symbol    CRELD2 [Similar Products]
 NCBI Protein Information    cysteine-rich with EGF-like domain protein 2
 UniProt Protein Name    Cysteine-rich with EGF-like domain protein 2
 Protein Family    Cysteine-rich with EGF-like domain protein
 UniProt Gene Name    CRELD2 [Similar Products]
 UniProt Entry Name    CREL2_HUMAN
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 UniProt Comments for CRELD2    CRELD2: May regulate transport of alpha4-beta2 neuronal acetylcholine receptor. Belongs to the CRELD family. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 22q13.33

Cellular Component: Golgi apparatus; extracellular space; endoplasmic reticulum

Molecular Function: protein binding; calcium ion binding
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 Research Articles on CRELD2    1. intravesicular acidification by V-ATPase regulates the secretion of CRELD2 without relying on the balance of intracellular calcium ions and the expression of endoplasmic reticulum chaperones such as GRP78 and protein disulfide isomerase.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CRELD2 antibodyDiseases associated with anti-CRELD2 antibody
 Reference Product  PubMed Publications
 MANF antibody  >2 publications with CRELD2 and MANF
 PDIA6 antibody  >1 publications with CRELD2 and PDIA6
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >3 publications with CRELD2 and Disease Models, Animal
 Heart Diseases Antibodies  >1 publications with CRELD2 and Heart Diseases
 Adenocarcinoma Antibodies  >1 publications with CRELD2 and Adenocarcinoma
 Cardiovascular Diseases Antibodies  >1 publications with CRELD2 and Cardiovascular Diseases
 Liver Diseases Antibodies  >1 publications with CRELD2 and Liver Diseases
 Hypertrophy Antibodies  >1 publications with CRELD2 and Hypertrophy
 Liver Neoplasms Antibodies  >1 publications with CRELD2 and Liver Neoplasms
 Liver Neoplasms, Experimental Antibodies  >1 publications with CRELD2 and Liver Neoplasms, Experimental
Organs/Tissues associated with anti-CRELD2 antibody
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >4 publications with CRELD2 and Bone
 Nerve Antibodies  >3 publications with CRELD2 and Nerve
 Connective Tissue Antibodies  >2 publications with CRELD2 and Connective Tissue
 Liver Antibodies  >2 publications with CRELD2 and Liver
 Heart Antibodies  >1 publications with CRELD2 and Heart
 Prostate Antibodies  >1 publications with CRELD2 and Prostate
 Thyroid Antibodies  >1 publications with CRELD2 and Thyroid
 Brain Antibodies  >1 publications with CRELD2 and Brain
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