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anti-CRMP1 antibody :: Rabbit CRMP1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2524043
Unit / Price
0.02 mL  /  $110 +1 FREE 8GB USB
0.06 mL  /  $150 +1 FREE 8GB USB
0.12 mL  /  $225 +1 FREE 8GB USB
0.2 mL  /  $360 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CRMP1, Polyclonal Antibody

★Popular Item★
 Also Known As   

CRMP1 Polyclonal Antibody

 Product Synonym Names    DRP1, DRP-1, CRMP-1, DPYSL1, ULIP-3
 Product Gene Name   

anti-CRMP1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    602462
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    Antigen affinity purification
 Concentration    0.6mg/mL (lot specific)
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 Immunogen    Synthetic peptide of human CRMP1
 Calculated Molecular Weight: 62kDa   
 Buffer    PBS with 0.05% sodium azide, 50% glycerol, pH7.3
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 Preparation and Storage    Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CRMP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CRMP1 antibody

   Collapsin response mediator protein 1, encoded by the CRMP1 gene, is a human protein of the CRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.
 Product Categories/Family for anti-CRMP1 antibody    Cancer; Cell biology
 Applications Tested/Suitable for anti-CRMP1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-CRMP1 antibody    WB: 1:500-1:1000
IHC: 1:25-1:100
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 Western Blot (WB) of anti-CRMP1 antibody    Western Blot analysis of Mouse brain tissue using CRMP1 Polyclonal Antibody at dilution of 1:500
anti-CRMP1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CRMP1 antibody    Immunohistochemistry of paraffin-embedded Human brain using CRMP1 Polyclonal Antibody at dilution of 1:15
anti-CRMP1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CRMP1. It may not necessarily be applicable to this product.
 NCBI GI #    39644816
 NCBI GeneID    1400
 NCBI Accession #    AAH07898.2 [Other Products]
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 UniProt Secondary Accession #    Q13024; Q4W5F1; Q96TC8; A0EJG6 [Other Products]
 UniProt Related Accession #    Q14194 [Other Products]
 Molecular Weight    74,262 Da
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 NCBI Official Full Name    CRMP1 protein, partial
 NCBI Official Synonym Full Names    collapsin response mediator protein 1
 NCBI Official Symbol    CRMP1 [Similar Products]
 NCBI Official Synonym Symbols   
DRP1; DRP-1; CRMP-1; DPYSL1; ULIP-3
[Similar Products]
 NCBI Protein Information    dihydropyrimidinase-related protein 1; dihydropyrimidinase-like 1; unc-33-like phosphoprotein 3
 UniProt Protein Name    Dihydropyrimidinase-related protein 1
 UniProt Synonym Protein Names   
Collapsin response mediator protein 1; CRMP-1; Unc-33-like phosphoprotein 3; ULIP-3
 Protein Family    Dihydropyrimidinase-related protein
 UniProt Gene Name    CRMP1 [Similar Products]
 UniProt Synonym Gene Names    DPYSL1; ULIP3; DRP-1; CRMP-1; ULIP-3 [Similar Products]
 UniProt Entry Name    DPYL1_HUMAN
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 NCBI Summary for CRMP1    This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CRMP1    CRMP-1: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Hydrolase; Cytoskeletal; Cell development/differentiation

Chromosomal Location of Human Ortholog: 4p16.1

Cellular Component: cell soma; cytoplasm; dendrite; microtubule organizing center; spindle; cytosol

Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides; protein binding

Biological Process: axon guidance; nervous system development; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; pyrimidine base catabolic process
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 Research Articles on CRMP1    1. in pilocarpine-induced animal model of epilepsy, CRMP-1 dynamically decreased in a range of 2 months. Thus, our results indicate that CRMP-1 may be involved in the development of TLE
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CRMP1 antibodyPathways associated with anti-CRMP1 antibody
 Reference Product  PubMed Publications
 SEMA3A antibody  >17 publications with CRMP1 and SEMA3A
 CDK5 antibody  >7 publications with CRMP1 and CDK5
 PLXNA1 antibody  >2 publications with CRMP1 and PLXNA1
 FYN antibody  >2 publications with CRMP1 and FYN
 CDK5R1 antibody  >1 publications with CRMP1 and CDK5R1
 PLXNA4 antibody  >1 publications with CRMP1 and PLXNA4
 PLXNA3 antibody  >1 publications with CRMP1 and PLXNA3
 DPYSL2 antibody  >1 publications with CRMP1 and DPYSL2
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 CRMPs In Sema3A Signaling Pathway antibodies  CRMPs In Sema3A Signaling Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Semaphorin Interactions Pathway antibodies  Semaphorin Interactions Pathway Diagram
Diseases associated with anti-CRMP1 antibodyOrgans/Tissues associated with anti-CRMP1 antibody
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >4 publications with CRMP1 and Neoplasm Metastasis
 Inflammation Antibodies  >3 publications with CRMP1 and Inflammation
 Disease Models, Animal Antibodies  >2 publications with CRMP1 and Disease Models, Animal
 Necrosis Antibodies  >2 publications with CRMP1 and Necrosis
 Movement Disorders Antibodies  >1 publications with CRMP1 and Movement Disorders
 Nerve Degeneration Antibodies  >1 publications with CRMP1 and Nerve Degeneration
 Congenital Abnormalities Antibodies  >1 publications with CRMP1 and Congenital Abnormalities
 Carcinoma, Hepatocellular Antibodies  >1 publications with CRMP1 and Carcinoma, Hepatocellular
 Liver Neoplasms Antibodies  >1 publications with CRMP1 and Liver Neoplasms
 Seizures Antibodies  >1 publications with CRMP1 and Seizures
 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >51 publications with CRMP1 and Nerve
 Brain Antibodies  >24 publications with CRMP1 and Brain
 Lung Antibodies  >10 publications with CRMP1 and Lung
 Embryonic Tissue Antibodies  >8 publications with CRMP1 and Embryonic Tissue
 Muscle Antibodies  >6 publications with CRMP1 and Muscle
 Heart Antibodies  >1 publications with CRMP1 and Heart
 Intestine Antibodies  >1 publications with CRMP1 and Intestine
 Testis Antibodies  >1 publications with CRMP1 and Testis
 Uncharacterized Tissue Antibodies  >1 publications with CRMP1 and Uncharacterized Tissue
 Eye Antibodies  >1 publications with CRMP1 and Eye
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