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anti-CRMP3 antibody :: Rabbit CRMP3 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS540664 anti-CRMP3 antibody
Unit / Price
0.1 mg Affinity-Purified  /  $390 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CRMP3, Polyclonal Antibody

 Also Known As   

CRMP3 Antibody

 Product Synonym Names    Collapsin response mediator protein 3; DPYSL4; DRP4; ULIP 4; UNC33 like phosphoprotein 4 antibody
 Product Gene Name   

anti-CRMP3 antibody

[Similar Products]
 Matching Pairs    Antibody: CRMP3 (MBS540664)
Positive Control: CRMP3 (MBS542713)
 Antibody/Peptide Pairs    CRMP3 peptide (MBS543603) is used for blocking the activity of CRMP3 antibody (MBS540664)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608407
 3D Structure    ModBase 3D Structure for O14531
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Cat, Human, Monkey, Mouse, Pig, Rat
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 Form/Format    Affinity Purified
 Concentration    0.55 ug/ul in antibody stabilization buffer (lot specific)
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 Immunogen    Synthetic peptide corresponding to amino acids 509-527 of Mouse CRMP3. The peptide was covalently modified to achieve the desired antigenicity before coupling to carrier protein.
Sequence: PAKPGSGTQARASCSGKIS
 Molecular Function    Axon guidance; pyrimidine nucelobase catabolic process; Nervous system development
 Structure    Homotetramer.
 Subcellular Location    Cytoplasm
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 Preparation and Storage    -20 degree C for long term storage
 Other Notes    Small volumes of anti-CRMP3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-CRMP3 antibody

   Affinity Purified Dihydropyrimidinase related protein 4 Antibody
Necessary for signaling by class 3 semaphorins and subsequent remodeling of cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
 Product Categories/Family for anti-CRMP3 antibody    Primary Antibodies; Neuroscience; CRMP3 Antibody
 Applications Tested/Suitable for anti-CRMP3 antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-CRMP3 antibody    Dot Blot: 1:10,000
ELISA: 1:10,000
Western Blot: 1:450
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NCBI/Uniprot data below describe general gene information for CRMP3. It may not necessarily be applicable to this product.
 NCBI GI #    190194363
 NCBI GeneID    10570
 NCBI Accession #    NP_006417.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_006426.2 [Other Products]
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 UniProt Primary Accession #    O14531 [Other Products]
 UniProt Secondary Accession #    O00240; Q5T0Q7; B2RMQ1; D3DRG5 [Other Products]
 UniProt Related Accession #    O14531 [Other Products]
 Molecular Weight    61,878 Da
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 NCBI Official Full Name    dihydropyrimidinase-related protein 4
 NCBI Official Synonym Full Names    dihydropyrimidinase like 4
 NCBI Official Symbol    DPYSL4 [Similar Products]
 NCBI Official Synonym Symbols   
CRMP3; DRP-4; ULIP4
[Similar Products]
 NCBI Protein Information    dihydropyrimidinase-related protein 4
 UniProt Protein Name    Dihydropyrimidinase-related protein 4
 UniProt Synonym Protein Names   
Collapsin response mediator protein 3; CRMP-3; UNC33-like phosphoprotein 4; ULIP-4
 UniProt Gene Name    DPYSL4 [Similar Products]
 UniProt Synonym Gene Names    CRMP3; ULIP4; DRP-4; CRMP-3; ULIP-4 [Similar Products]
 UniProt Entry Name    DPYL4_HUMAN
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 UniProt Comments for CRMP3    CRMP-3: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 10q26

Cellular Component: cytosol

Molecular Function: filamin binding; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; protein binding

Biological Process: metabolic process; nervous system development
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 Research Articles on CRMP3    1. DPYSL4 is a novel apoptosis-inducible factor controlled by p53 in response to DNA damage
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CRMP3 antibodyDiseases associated with anti-CRMP3 antibody
 Products by Pathway  Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 CRMPs In Sema3A Signaling Pathway antibodies  CRMPs In Sema3A Signaling Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Semaphorin Interactions Pathway antibodies  Semaphorin Interactions Pathway Diagram
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >5 publications with CRMP3 and Nervous System Diseases
 Hyperplasia Antibodies  >1 publications with CRMP3 and Hyperplasia
 Carcinoma, Hepatocellular Antibodies  >1 publications with CRMP3 and Carcinoma, Hepatocellular
 Nerve Degeneration Antibodies  >1 publications with CRMP3 and Nerve Degeneration
 Neurotoxicity Syndromes Antibodies  >1 publications with CRMP3 and Neurotoxicity Syndromes
 Liver Neoplasms Antibodies  >1 publications with CRMP3 and Liver Neoplasms
 Poisoning Antibodies  >1 publications with CRMP3 and Poisoning
 Liver Diseases Antibodies  >1 publications with CRMP3 and Liver Diseases
 Prenatal Exposure Delayed Effects Antibodies  >1 publications with CRMP3 and Prenatal Exposure Delayed Effects
Organs/Tissues associated with anti-CRMP3 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >16 publications with CRMP3 and Brain
 Embryonic Tissue Antibodies  >4 publications with CRMP3 and Embryonic Tissue
 Liver Antibodies  >2 publications with CRMP3 and Liver
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