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anti-CRNN antibody :: Rabbit CRNN Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS1493743
Western Blot (WB)
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CRNN, Polyclonal Antibody

★Popular Item★
 Also Known As   

CRNN Antibody

 Product Synonym Names    Cornulin; CRNN; C1orf10; DRC1; PDRC1; SEP53; 53 kDa putative calcium-binding protein; 53 kDa squamous epithelial-induced stress protein; 58 kDa heat shock protein; Squamous epithelial heat shock protein 53; Tumor-related protein
 Product Gene Name   

anti-CRNN antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    611312
 3D Structure    ModBase 3D Structure for Q9UBG3
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Purity/Purification    >95%, Protein G Purified
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 Storage Buffer    Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Conjugate    Non-conjugated
 Immunogen    Recombinant human Cornulin protein
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-164097
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CRNN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CRNN antibody

   Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest.
 Applications Tested/Suitable for anti-CRNN antibody   

ELISA (EIA), Western Blot (WB)

 Application Notes for anti-CRNN antibody    Recommended dilution: WB:1:500-2000
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 Western Blot (WB) of anti-CRNN antibody    Western blot
All lanes: CRNN antibody at 12ug/ml
Lane 1:HepG2 whole cell lysate
Lane 2:Mouse heart tissue
Lane 3:rat skeletal muscle tissue
Secondary
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 54kDa
Observed band size: 54kDa

anti-CRNN antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CRNN. It may not necessarily be applicable to this product.
 NCBI GI #    7706635
 NCBI GeneID    49860
 NCBI Accession #    NP_057274.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_016190.2 [Other Products]
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 UniProt Primary Accession #    Q9UBG3 [Other Products]
 UniProt Secondary Accession #    Q8N613; B2RE60 [Other Products]
 UniProt Related Accession #    Q9UBG3 [Other Products]
 Molecular Weight    53,533 Da
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 NCBI Official Full Name    cornulin
 NCBI Official Synonym Full Names    cornulin
 NCBI Official Symbol    CRNN [Similar Products]
 NCBI Official Synonym Symbols   
DRC1; PDRC1; SEP53; C1orf10
[Similar Products]
 NCBI Protein Information    cornulin
 UniProt Protein Name    Cornulin
 UniProt Synonym Protein Names   
53 kDa putative calcium-binding protein; 53 kDa squamous epithelial-induced stress protein; 58 kDa heat shock protein; Squamous epithelial heat shock protein 53; Tumor-related protein
 Protein Family    Cornulin
 UniProt Gene Name    CRNN [Similar Products]
 UniProt Synonym Gene Names    C1orf10; DRC1; PDRC1; SEP53 [Similar Products]
 UniProt Entry Name    CRNN_HUMAN
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 NCBI Summary for CRNN    This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation. [provided by RefSeq, Jan 2009]
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 UniProt Comments for CRNN    CRNN: Survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and release of calcium. When overexpressed in oral squamous carcinom cell lines, regulates negatively cell proliferation by the induction of G1 arrest. Belongs to the S100-fused protein family.

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; membrane

Molecular Function: calcium ion binding

Biological Process: cell-cell adhesion; response to heat
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 Research Articles on CRNN    1. Loss of CRNN expression correlated with advanced tumor length, greater tumor invasion depth, lymph node metastasis, and poor survival in patients with esophageal squamous cell carcinoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CRNN antibodyDiseases associated with anti-CRNN antibody
 Reference Product  PubMed Publications
 S100A7A antibody  >1 publications with CRNN and S100A7A
 Disease Name  Pubmed Publications
 Neoplasms, Experimental Antibodies  >2 publications with CRNN and Neoplasms, Experimental
 Renal Insufficiency Antibodies  >1 publications with CRNN and Renal Insufficiency
 Anemia Antibodies  >1 publications with CRNN and Anemia
 Neurodegenerative Diseases Antibodies  >1 publications with CRNN and Neurodegenerative Diseases
 Kidney Diseases Antibodies  >1 publications with CRNN and Kidney Diseases
 Inflammation Antibodies  >1 publications with CRNN and Inflammation
Organs/Tissues associated with anti-CRNN antibody
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >5 publications with CRNN and Skin
 Esophagus Antibodies  >4 publications with CRNN and Esophagus
 Mouth Antibodies  >2 publications with CRNN and Mouth
 Larynx Antibodies  >1 publications with CRNN and Larynx
 Muscle Antibodies  >1 publications with CRNN and Muscle
 Cervix Antibodies  >1 publications with CRNN and Cervix
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