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anti-CRP1 antibody :: Rabbit CRP1 / CSRP1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS244409
Unit / Price
0.05 mL  /  $495 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CRP1 / CSRP1, Polyclonal Antibody

 Also Known As   

Rabbit Polyclonal (IgG) to Human CRP1 / CSRP1

 Product Synonym Names    Anti-CRP1 / CSRP1 Antibody (aa51-100) IHC-plus; CSRP1; CSRP; CYRP; Cysteine-rich protein 1; D1S181E; CRP1; LIM-domain protein; Human CRP1; CSRP1
 Product Gene Name   

anti-CRP1 antibody

[Similar Products]
 Product Synonym Gene Name    CSRP1 [Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    123876
 3D Structure    ModBase 3D Structure for P21291
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    CRP1 Antibody detects endogenous levels of total CRP1 protein.
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic peptide from human CRP1 (aa51-100).
 Immunogen    CRP1 / CSRP1 antibody was raised against synthetic peptide from human CRP1 (aa51-100).
 Antigen Modification    aa51-100
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 Preparation and Storage    Store at -20 degree C for up to one year.
 Other Notes    Small volumes of anti-CRP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-CRP1 antibody

   CSRP1 is a member of the CSRP family of genes encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in CRP1 is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation Other genes in the family include CSRP2 and CSRP3.
 Applications Tested/Suitable for anti-CRP1 antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)

 Application Notes for anti-CRP1 antibody    ELISA (1:20000), IHC-P (5 ug/ml), WB (1:500 - 1:1000)
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 Immunohistochemistry (IHC) of anti-CRP1 antibody    Anti-CRP1 / CSRP1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
anti-CRP1 antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-CRP1 antibody    Western blot of extracts from HeLa/HepG2/COLO/Jurkat cells, using CRP1 Antibody. The lane on the right is treated with the synthesized peptide.
anti-CRP1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CRP1. It may not necessarily be applicable to this product.
 NCBI GI #    4758086
 NCBI GeneID    1465
 NCBI Accession #    NP_004069.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004078.2 [Other Products]
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 UniProt Primary Accession #    P21291 [Other Products]
 UniProt Secondary Accession #    Q5U0J2; A8K268 [Other Products]
 UniProt Related Accession #    P21291 [Other Products]
 Molecular Weight    20,567 Da
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 NCBI Official Full Name    cysteine and glycine-rich protein 1 isoform 1
 NCBI Official Synonym Full Names    cysteine and glycine-rich protein 1
 NCBI Official Symbol    CSRP1 [Similar Products]
 NCBI Official Synonym Symbols   
CRP; CRP1; CSRP; CYRP; D1S181E; HEL-141
[Similar Products]
 NCBI Protein Information    cysteine and glycine-rich protein 1; LIM-domain protein; cysteine-rich protein 1; epididymis luminal protein 141
 UniProt Protein Name    Cysteine and glycine-rich protein 1
 UniProt Synonym Protein Names   
Cysteine-rich protein 1; CRP; CRP1; Epididymis luminal protein 141; HEL-141
 Protein Family    Cruciform DNA-recognizing protein
 UniProt Gene Name    CSRP1 [Similar Products]
 UniProt Synonym Gene Names    CSRP; CYRP; CRP; CRP1; HEL-141 [Similar Products]
 UniProt Entry Name    CSRP1_HUMAN
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 NCBI Summary for CRP1    This gene encodes a member of the cysteine-rich protein (CSRP) family. This gene family includes a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]
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 UniProt Comments for CRP1    CSRP1: a LIM protein. Involved in the noncanonical Wnt pathway, which coordinates cell behaviors during dynamic morphogenetic movements of tissues and organs. Interacts with Dishevelled 2 (Dvl2) and Diversin (Div) in zebrafish. Displays coordinate serum induction with c-myc.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: focal adhesion; nucleus

Molecular Function: zinc ion binding
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 Research Articles on CRP1    1. A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CRP1 antibodyDiseases associated with anti-CRP1 antibody
 Reference Product  PubMed Publications
 CRP antibody  >7 publications with CRP1 and CRP
 TAGLN antibody  >1 publications with CRP1 and TAGLN
 DVL2 antibody  >1 publications with CRP1 and DVL2
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >1 publications with CRP1 and Nervous System Diseases
 Death Antibodies  >1 publications with CRP1 and Death
 Cell Transformation, Neoplastic Antibodies  >1 publications with CRP1 and Cell Transformation, Neoplastic
 Hyperplasia Antibodies  >1 publications with CRP1 and Hyperplasia
 Liver Diseases Antibodies  >1 publications with CRP1 and Liver Diseases
 Liver Neoplasms Antibodies  >1 publications with CRP1 and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >1 publications with CRP1 and Carcinoma, Hepatocellular
 Prostatic Neoplasms Antibodies  >1 publications with CRP1 and Prostatic Neoplasms
Organs/Tissues associated with anti-CRP1 antibody
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >10 publications with CRP1 and Muscle
 Vascular Antibodies  >5 publications with CRP1 and Vascular
 Embryonic Tissue Antibodies  >4 publications with CRP1 and Embryonic Tissue
 Heart Antibodies  >4 publications with CRP1 and Heart
 Liver Antibodies  >2 publications with CRP1 and Liver
 Spinal Cord Antibodies  >2 publications with CRP1 and Spinal Cord
 Brain Antibodies  >2 publications with CRP1 and Brain
 Bone Antibodies  >1 publications with CRP1 and Bone
 Bladder Antibodies  >1 publications with CRP1 and Bladder
 Ganglia Antibodies  >1 publications with CRP1 and Ganglia
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