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anti-CSK antibody :: Rabbit CSK (pS364) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS822339 anti-CSK antibody
Unit / Price
0.03 mL  /  $165 +1 FREE 8GB USB
0.1 mL  /  $245 +1 FREE 8GB USB
0.2 mL  /  $350 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CSK (pS364), Polyclonal Antibody

 Also Known As   

Anti-CSK (pS364) Antibody

 Product Synonym Names    Tyrosine-protein kinase CSK; C-Src kinase; Protein-tyrosine kinase CYL
 Product Gene Name   

anti-CSK antibody

[Similar Products]
 Antibody/Peptide Pairs    CSK (pS364) peptide (MBS824307) is used for blocking the activity of CSK (pS364) antibody (MBS822339)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    124095
 3D Structure    ModBase 3D Structure for P41240
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat, Bovine, Chicken, Zebrafish
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 Specificity    Recognizes endogenous levels of CSK (pS364) protein.
 Purity/Purification    The antibody was purified by immunogen affinity chromatography.
 Form/Format    Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
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 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CSK. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-CSK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CSK antibody

   Rabbit polyclonal antibody to CSK (pS364)
 Applications Tested/Suitable for anti-CSK antibody   

Western Blot (WB)

 Application Notes for anti-CSK antibody    WB (1/500 - 1/1000)
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 Western Blot (WB) of anti-CSK antibody    anti-CSK antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CSK. It may not necessarily be applicable to this product.
 NCBI GI #    187475373
 NCBI GeneID    1445
 NCBI Accession #    NP_001120662.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001127190.1 [Other Products]
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 UniProt Primary Accession #    P41240 [Other Products]
 UniProt Secondary Accession #    Q2M3N2; Q6FGZ6 [Other Products]
 UniProt Related Accession #    P41240 [Other Products]
 Molecular Weight    50,704 Da
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 NCBI Official Full Name    tyrosine-protein kinase CSK
 NCBI Official Synonym Full Names    c-src tyrosine kinase
 NCBI Official Symbol    CSK [Similar Products]
 NCBI Protein Information    tyrosine-protein kinase CSK; C-Src kinase; protein-tyrosine kinase CYL
 UniProt Protein Name    Tyrosine-protein kinase CSK
 UniProt Synonym Protein Names   
C-Src kinase; Protein-tyrosine kinase CYL
 Protein Family    Chloroplast sensor kinase
 UniProt Gene Name    CSK [Similar Products]
 UniProt Entry Name    CSK_HUMAN
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 UniProt Comments for CSK    CSK: a tyrosine kinase of the Csk family that phosphorylates and inhibits Src family kinases. Specifically phosphorylates Y504 on LCK, which acts as a negative regulatory site. Csk and the phospho-tyrosine phosphatase CD45 reciprocally regulate phosphorylation of the inhibitory tyrosine of the Src family kinases Lck and Fyn during T-cell receptor mediated signaling during thymic development.

Protein type: Protein kinase, tyrosine (non-receptor); EC 2.7.10.2; Kinase, protein; Protein kinase, TK; TK group; Csk family

Chromosomal Location of Human Ortholog: 15q24.1

Cellular Component: extrinsic to internal side of plasma membrane; cytoplasm; plasma membrane; intercellular junction; cytosol; lipid raft

Molecular Function: protein C-terminus binding; identical protein binding; protein binding; protein-tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; protein phosphatase binding; ATP binding; receptor binding

Biological Process: epidermal growth factor receptor signaling pathway; negative regulation of kinase activity; negative regulation of phagocytosis; platelet activation; cell migration; central nervous system development; negative regulation of Golgi to plasma membrane protein transport; T cell receptor signaling pathway; protein amino acid phosphorylation; regulation of cell proliferation; regulation of cytokine production; negative regulation of cell proliferation; positive regulation of MAP kinase activity; T cell costimulation; negative regulation of interleukin-6 production; oligodendrocyte differentiation; morphogenesis of an epithelium; innate immune response; brain development; cell differentiation; negative regulation of bone resorption; blood coagulation; transmembrane receptor protein tyrosine kinase signaling pathway
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 Research Articles on CSK    1. the activity of SIRT2 is regulated by c-Src through post-translational modifications.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CSK antibodyPathways associated with anti-CSK antibody
 Reference Product  PubMed Publications
 SRC antibody  >1453 publications with CSK and SRC
 FYN antibody  >156 publications with CSK and FYN
 LYN antibody  >103 publications with CSK and LYN
 LCK antibody  >100 publications with CSK and LCK
 PAG1 antibody  >54 publications with CSK and PAG1
 PTPRC antibody  >27 publications with CSK and PTPRC
 PXN antibody  >25 publications with CSK and PXN
 HCK antibody  >24 publications with CSK and HCK
 SHC1 antibody  >12 publications with CSK and SHC1
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 BCR Signaling Pathway antibodies  BCR Signaling Pathway Diagram
 CXCR4-mediated Signaling Events Pathway antibodies  CXCR4-mediated Signaling Events Pathway Diagram
 Costimulation By The CD28 Family Pathway antibodies  Costimulation By The CD28 Family Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies  Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
 Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies  Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
 GAB1 Signalosome Pathway antibodies  GAB1 Signalosome Pathway Diagram
Diseases associated with anti-CSK antibodyOrgans/Tissues associated with anti-CSK antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >187 publications with CSK and Inflammation
 Necrosis Antibodies  >118 publications with CSK and Necrosis
 Heart Diseases Antibodies  >111 publications with CSK and Heart Diseases
 Kidney Diseases Antibodies  >97 publications with CSK and Kidney Diseases
 Breast Neoplasms Antibodies  >88 publications with CSK and Breast Neoplasms
 Hypertension Antibodies  >72 publications with CSK and Hypertension
 Adenocarcinoma Antibodies  >64 publications with CSK and Adenocarcinoma
 Cell Transformation, Neoplastic Antibodies  >63 publications with CSK and Cell Transformation, Neoplastic
 Intestinal Neoplasms Antibodies  >50 publications with CSK and Intestinal Neoplasms
 Neoplasms, Experimental Antibodies  >46 publications with CSK and Neoplasms, Experimental
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >611 publications with CSK and Blood
 Vascular Antibodies  >204 publications with CSK and Vascular
 Brain Antibodies  >195 publications with CSK and Brain
 Bone Antibodies  >182 publications with CSK and Bone
 Kidney Antibodies  >175 publications with CSK and Kidney
 Lung Antibodies  >122 publications with CSK and Lung
 Heart Antibodies  >113 publications with CSK and Heart
 Liver Antibodies  >96 publications with CSK and Liver
 Bone Marrow Antibodies  >85 publications with CSK and Bone Marrow
 Skin Antibodies  >76 publications with CSK and Skin
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