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anti-CSNK1G1 antibody :: Rabbit anti-Human CSNK1G1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7045462
Unit / Price
0.05 mL  /  $120 +1 FREE 8GB USB
0.1 mL  /  $160 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CSNK1G1, Polyclonal Antibody

★Popular Item★
 Also Known As   

CSNK1G1 Antibody

 Product Synonym Names    Casein kinase I isoform gamma-1; CKI-gamma 1; CSNK1G1
 Product Gene Name   

anti-CSNK1G1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    606274
 3D Structure    ModBase 3D Structure for Q9HCP0
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Antigen Affinity Purified
 Form/Format    Liquid
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 Species    Human
 Immunogen    Recombinant human Casein kinase I isoform gamma-1 protein (C-125AA)
 Conjugate    Non-conjugated
 Buffer    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-18493 / sc-23784
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CSNK1G1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CSNK1G1 antibody

   Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). Phosphorylates CLSPN.
 Applications Tested/Suitable for anti-CSNK1G1 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-CSNK1G1 antibody    Western blot
All lanes:  CSNK1G1antibody at 1.13ug/ml
Lane 1 : Jurkat whole cell lysate
Lane 2 : Hela whole cell lysate
Lane 3 : MCF7 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/10000 dilution
Predicted band size: 49,46 kDa
Observed band size: 49 kDa

anti-CSNK1G1 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CSNK1G1 antibody    Immunohistochemistry of paraffin-embedded human breast cancer using MBS7045462 at dilution 1:100
anti-CSNK1G1 antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CSNK1G1 antibody    Immunohistochemistry of paraffin-embedded human endometrial cancer using MBS7045462 at dilution 1:100
anti-CSNK1G1 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CSNK1G1. It may not necessarily be applicable to this product.
 NCBI GI #    98986450
 NCBI GeneID    53944
 NCBI Accession #    NP_071331.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_022048.4 [Other Products]
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 UniProt Primary Accession #    Q9HCP0 [Other Products]
 UniProt Secondary Accession #    Q5JPH1; Q96AE9; Q9HCP1 [Other Products]
 UniProt Related Accession #    Q9HCP0 [Other Products]
 Molecular Weight    45,414 Da
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 NCBI Official Full Name    casein kinase I isoform gamma-1 isoform 1
 NCBI Official Synonym Full Names    casein kinase 1 gamma 1
 NCBI Official Symbol    CSNK1G1 [Similar Products]
 NCBI Official Synonym Symbols   
CK1gamma1
[Similar Products]
 NCBI Protein Information    casein kinase I isoform gamma-1
 UniProt Protein Name    Casein kinase I isoform gamma-1
 Protein Family    Casein kinase
 UniProt Gene Name    CSNK1G1 [Similar Products]
 UniProt Synonym Gene Names    CKI-gamma 1 [Similar Products]
 UniProt Entry Name    KC1G1_HUMAN
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 NCBI Summary for CSNK1G1    This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE). [provided by RefSeq, Jul 2016]
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 UniProt Comments for CSNK1G1    CK1G1: an ubiquitous protein kinase of the CK1 family. Involved in growth and morphogenesis. Two splice variant isoforms have been described.

Protein type: Protein kinase, Ser/Thr (non-receptor); Protein kinase, CK1; EC 2.7.11.1; Kinase, protein; CK1 group; CK1 family

Chromosomal Location of Human Ortholog: 15q22.1-q22.31

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; protein serine/threonine kinase activity

Biological Process: endocytosis; peptidyl-serine phosphorylation; regulation of cell shape; Wnt receptor signaling pathway
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 Research Articles on CSNK1G1    1. CK1gamma1 phosphorylates p65 and consequently promotes its degradation by ubiquitin E3 ligases CUL2 and COMMD1.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with anti-CSNK1G1 antibodyDiseases associated with anti-CSNK1G1 antibody
 Products by Pathway  Pathway Diagram
 Canonical Wnt Signaling Pathway antibodies  Canonical Wnt Signaling Pathway Diagram
 FoxO Family Signaling Pathway antibodies  FoxO Family Signaling Pathway Diagram
 Hedgehog Signaling Events Mediated By Gli Proteins Pathway antibodies  Hedgehog Signaling Events Mediated By Gli Proteins Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 Hedgehog Signaling Pathway antibodies  Hedgehog Signaling Pathway Diagram
 P53 Pathway antibodies  P53 Pathway Diagram
 Disease Name  Pubmed Publications
 Disease Models, Animal Antibodies  >1 publications with CSNK1G1 and Disease Models, Animal
 Depressive Disorder Antibodies  >1 publications with CSNK1G1 and Depressive Disorder
 Nervous System Diseases Antibodies  >1 publications with CSNK1G1 and Nervous System Diseases
Organs/Tissues associated with anti-CSNK1G1 antibody
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1 publications with CSNK1G1 and Vascular
 Brain Antibodies  >1 publications with CSNK1G1 and Brain
 Testis Antibodies  >1 publications with CSNK1G1 and Testis
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