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anti-CX3CL1 antibody :: Rabbit anti-Human CX3CL1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS175324
Western Blot (WB)
Unit / Price
0.1 mg  /  $245 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CX3CL1, Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Anti-Chemokin (C-X3-C motif) ligand 1, Fractalkine/CX3L1

 Product Synonym Names    Fractalkine; chemokine(C-X3-C motif) ligand 1; A 152E5.2 antibody; AB030188 antibody; ABCD 3 antibody; ABCD3 antibody; AI848747 antibody; C-X3-C motif chemokine 1 antibody; C3Xkine antibody; Chemokine(C-X3-C motif) ligand 1 antibody; Chemokine C X3 C motif ligand 1 antibody; Chemokine CX3C Motif Ligand 1 antibody; CX3C membrane anchored chemokine antibody; CX3C membrane-anchored chemokine antibody; CX3CL1 antibody; CXC 3 antibody; CXC3 antibody; CXC3C antibody; D8Bwg0439e antibody; FKN antibody; Fractalkine antibody; Neurotactin antibody; NTN antibody; NTT antibody; Processed fractalkine antibody; SCYD 1 antibody; SCYD1 antibody; Small inducible cytokine D1 antibody; Small inducible cytokine subfamily D(Cys X3 Cys) member 1 antibody; small inducible cytokine subfamily D(Cys-X3-Cys), member 1(fractalkine, neurotactin) antibody; Small inducible cytokine subfamily D member 1 antibody; Small-inducible cytokine D1 antibody; X3CL1_HUMAN antibody
 Product Gene Name   

anti-CX3CL1 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    601880
 3D Structure    ModBase 3D Structure for P78423
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Purity/Purification    Immunogen affinity purified.
 Form/Format    Lyophilized
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 Immunogen    A synthetic peptide corresponding to a sequence at the N-terminus of human CX3CL1 (50-64aa HYQQNQASCGKRAII).
 Contents    Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
 Reconstitution    Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
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 Preparation and Storage    At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CX3CL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CX3CL1 antibody

   Description: Rabbit IgG polyclonal antibody for Fractalkine(CX3CL1) detection. Tested with WB in Human.
Background: Chemokine(C-X3-C motif) ligand 1, also known as CX3CL1, is a large cytokine protein. It is said to be the only known member of the CX3C chemokine family. It is also commonly known under the names fractalkine(in humans) and neurotactin(in mice). Its gene is mapped to the long arm of chromosome 8. Being the large protein, it has got 373 amino acids. Imai et al.(1997) identified a 7-transmembrane high-affinity receptor(CX3CR1; 601470) for fractalkine and showed that it mediates both the adhesive and migratory functions of fractalkine.
 Applications Tested/Suitable for anti-CX3CL1 antibody   

Western Blot (WB)

 Application Notes for anti-CX3CL1 antibody    WB:
Concentration: 1ug/ml
Tested Species: Hu
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 Western Blot (WB) of anti-CX3CL1 antibody    Anti-CX3CL1 antibody, MBS175324, Western blotting
Lane 1: Recombinant Human Fractalkine Protein 10ng
Lane 2: Recombinant Human Fractalkine Protein 5ng
Lane 3: Recombinant Human Fractalkine Protein 2.5ng
anti-CX3CL1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CX3CL1. It may not necessarily be applicable to this product.
 NCBI GI #    6175080
 NCBI GeneID    6376
 NCBI Accession #    P78423.1 [Other Products]
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 UniProt Primary Accession #    P78423 [Other Products]
 UniProt Secondary Accession #    O00672 [Other Products]
 UniProt Related Accession #    P78423 [Other Products]
 Molecular Weight    42,203 Da
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 NCBI Official Full Name    Fractalkine
 NCBI Official Synonym Full Names    chemokine (C-X3-C motif) ligand 1
 NCBI Official Symbol    CX3CL1 [Similar Products]
 NCBI Official Synonym Symbols   
NTN; NTT; CXC3; CXC3C; SCYD1; ABCD-3; C3Xkine; fractalkine; neurotactin
[Similar Products]
 NCBI Protein Information    fractalkine; C-X3-C motif chemokine 1; small-inducible cytokine D1; CX3C membrane-anchored chemokine; small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin)
 UniProt Protein Name    Fractalkine
 UniProt Synonym Protein Names   
C-X3-C motif chemokine 1; CX3C membrane-anchored chemokine; Neurotactin; Small-inducible cytokine D1Cleaved into the following chain:Processed fractalkine
 Protein Family    Fractalkine
 UniProt Gene Name    CX3CL1 [Similar Products]
 UniProt Synonym Gene Names    FKN; NTT; SCYD1 [Similar Products]
 UniProt Entry Name    X3CL1_HUMAN
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 UniProt Comments for CX3CL1    CX3CL1: The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1. Belongs to the intercrine delta family.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16q13

Cellular Component: extracellular space; cell surface; integral to membrane; plasma membrane; extracellular region

Molecular Function: protein binding; chemokine activity; receptor binding

Biological Process: positive regulation of transforming growth factor-beta1 production; neutrophil chemotaxis; leukocyte chemotaxis; cytokine and chemokine mediated signaling pathway; defense response; chemotaxis; angiogenesis involved in wound healing; macrophage chemotaxis; leukocyte adhesive activation; positive regulation of angiogenesis; positive regulation of calcium-independent cell-cell adhesion; immune response; cell adhesion; lymphocyte chemotaxis; positive regulation of inflammatory response
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 Research Articles on CX3CL1    1. Low expression of CX3CL1 is gender-specifically associated with soft tissue sarcoma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CX3CL1 antibodyPathways associated with anti-CX3CL1 antibody
 Reference Product  PubMed Publications
 CX3CR1 antibody  >465 publications with CX3CL1 and CX3CR1
 CCR2 antibody  >54 publications with CX3CL1 and CCR2
 CCR5 antibody  >35 publications with CX3CL1 and CCR5
 CXCR4 antibody  >34 publications with CX3CL1 and CXCR4
 CXCR3 antibody  >26 publications with CX3CL1 and CXCR3
 CCR1 antibody  >17 publications with CX3CL1 and CCR1
 CCR3 antibody  >12 publications with CX3CL1 and CCR3
 CXCR6 antibody  >11 publications with CX3CL1 and CXCR6
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Direct P53 Effectors Pathway antibodies  Direct P53 Effectors Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 Peptide Ligand-binding Receptors Pathway antibodies  Peptide Ligand-binding Receptors Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
Diseases associated with anti-CX3CL1 antibodyOrgans/Tissues associated with anti-CX3CL1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >322 publications with CX3CL1 and Inflammation
 Necrosis Antibodies  >174 publications with CX3CL1 and Necrosis
 Cardiovascular Diseases Antibodies  >140 publications with CX3CL1 and Cardiovascular Diseases
 Brain Diseases Antibodies  >91 publications with CX3CL1 and Brain Diseases
 Atherosclerosis Antibodies  >84 publications with CX3CL1 and Atherosclerosis
 Pain Antibodies  >56 publications with CX3CL1 and Pain
 Kidney Diseases Antibodies  >55 publications with CX3CL1 and Kidney Diseases
 Liver Diseases Antibodies  >46 publications with CX3CL1 and Liver Diseases
 Heart Diseases Antibodies  >45 publications with CX3CL1 and Heart Diseases
 Myocardial Ischemia Antibodies  >37 publications with CX3CL1 and Myocardial Ischemia
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >176 publications with CX3CL1 and Brain
 Muscle Antibodies  >88 publications with CX3CL1 and Muscle
 Kidney Antibodies  >83 publications with CX3CL1 and Kidney
 Lung Antibodies  >80 publications with CX3CL1 and Lung
 Liver Antibodies  >61 publications with CX3CL1 and Liver
 Heart Antibodies  >58 publications with CX3CL1 and Heart
 Nerve Antibodies  >47 publications with CX3CL1 and Nerve
 Skin Antibodies  >41 publications with CX3CL1 and Skin
 Intestine Antibodies  >32 publications with CX3CL1 and Intestine
 Eye Antibodies  >26 publications with CX3CL1 and Eye
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