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anti-CXCL1 antibody :: Rabbit anti-Human CXCL1 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS8241868
Western Blot (WB)
Unit / Price
0.03 mL  /  $155 +1 FREE 8GB USB
0.1 mL  /  $220 +1 FREE 8GB USB
0.2 mL  /  $295 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CXCL1, Polyclonal Antibody

★Popular Item★
 Also Known As   

Anti-CXCL1 Antibody

 Product Synonym Names    GRO; GRO1; GROA; MGSA; SCYB1; Growth-regulated alpha protein; C-X-C motif chemokine 1; GRO-alpha(1-73); Melanoma growth stimulatory activity; MGSA; Neutrophil-activating protein 3; NAP-3
 Product Gene Name   

anti-CXCL1 antibody

[Similar Products]
 Antibody/Peptide Pairs    CXCL1 peptide (MBS8244222) is used for blocking the activity of CXCL1 antibody (MBS8241868)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    155730
 3D Structure    ModBase 3D Structure for P09341
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    Recognizes endogenous levels of CXCL1 protein.
 Purity/Purification    The antibody was purified by affinity chromatography.
 Form/Format    Liquid in PBS, pH 7.3, 0.2% BSA, and 0.02% Sodium Azide.
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 Immunogen    KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CXCL1. The exact sequence is proprietary.
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
 Other Notes    Small volumes of anti-CXCL1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CXCL1 antibody

   Rabbit polyclonal antibody to CXCL1
 Applications Tested/Suitable for anti-CXCL1 antibody   

Western Blot (WB)

 Application Notes for anti-CXCL1 antibody    Western Blot: (1/500 - 1/1000)
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 Western Blot (WB) of anti-CXCL1 antibody    Western blot analysis of CXCL1 expression in Jurkat (A), Hela (B) whole cell lysates.
anti-CXCL1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CXCL1. It may not necessarily be applicable to this product.
 NCBI GI #    121622
 NCBI GeneID    2919
 NCBI Accession #    P09341.1 [Other Products]
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 UniProt Primary Accession #    P09341 [Other Products]
 UniProt Secondary Accession #    Q9UCR7 [Other Products]
 UniProt Related Accession #    P09341 [Other Products]
 Molecular Weight    11,301 Da
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 NCBI Official Full Name    Growth-regulated alpha protein
 NCBI Official Synonym Full Names    C-X-C motif chemokine ligand 1
 NCBI Official Symbol    CXCL1 [Similar Products]
 NCBI Official Synonym Symbols   
FSP; GRO1; GROa; MGSA; NAP-3; SCYB1; MGSA-a
[Similar Products]
 NCBI Protein Information    growth-regulated alpha protein
 UniProt Protein Name    Growth-regulated alpha protein
 UniProt Synonym Protein Names   
C-X-C motif chemokine 1; GRO-alpha(1-73); Melanoma growth stimulatory activity; MGSA
 Protein Family    Growth-regulated alpha protein
 UniProt Gene Name    CXCL1 [Similar Products]
 UniProt Synonym Gene Names    GRO; GRO1; GROA; MGSA; SCYB1; MGSA; NAP-3 [Similar Products]
 UniProt Entry Name    GROA_HUMAN
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 NCBI Summary for CXCL1    This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
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 UniProt Comments for CXCL1    CXCL1: Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular region; extracellular space; intracellular

Molecular Function: chemokine activity; CXCR chemokine receptor binding; enzyme activator activity; growth factor activity; receptor binding

Biological Process: actin cytoskeleton organization and biogenesis; cell proliferation; chemotaxis; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; negative regulation of cell proliferation; nervous system development; positive regulation of catalytic activity; response to lipopolysaccharide; signal transduction
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 Research Articles on CXCL1    1. High CXCL1 expression is a poor prognostic biomarker in metastatic colorectal cancer.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CXCL1 antibodyPathways associated with anti-CXCL1 antibody
 Reference Product  PubMed Publications
 CXCR2 antibody  >393 publications with CXCL1 and CXCR2
 CCL5 antibody  >297 publications with CXCL1 and CCL5
 CXCL10 antibody  >260 publications with CXCL1 and CXCL10
 CCL20 antibody  >128 publications with CXCL1 and CCL20
 CXCR1 antibody  >123 publications with CXCL1 and CXCR1
 CXCL12 antibody  >103 publications with CXCL1 and CXCL12
 CXCL11 antibody  >40 publications with CXCL1 and CXCL11
 CCR1 antibody  >37 publications with CXCL1 and CCR1
 CCR5 antibody  >36 publications with CXCL1 and CCR5
 CXCR3 antibody  >36 publications with CXCL1 and CXCR3
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway antibodies  Epithelial Cell Signaling In Helicobacter Pylori Infection Pathway Diagram
Diseases associated with anti-CXCL1 antibodyOrgans/Tissues associated with anti-CXCL1 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1372 publications with CXCL1 and Inflammation
 Necrosis Antibodies  >639 publications with CXCL1 and Necrosis
 Disease Models, Animal Antibodies  >510 publications with CXCL1 and Disease Models, Animal
 Lung Diseases Antibodies  >388 publications with CXCL1 and Lung Diseases
 Cardiovascular Diseases Antibodies  >228 publications with CXCL1 and Cardiovascular Diseases
 Gastrointestinal Diseases Antibodies  >200 publications with CXCL1 and Gastrointestinal Diseases
 Lung Injury Antibodies  >194 publications with CXCL1 and Lung Injury
 Pneumonia Antibodies  >142 publications with CXCL1 and Pneumonia
 Fibrosis Antibodies  >114 publications with CXCL1 and Fibrosis
 Reperfusion Injury Antibodies  >109 publications with CXCL1 and Reperfusion Injury
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1420 publications with CXCL1 and Blood
 Lung Antibodies  >579 publications with CXCL1 and Lung
 Vascular Antibodies  >419 publications with CXCL1 and Vascular
 Liver Antibodies  >220 publications with CXCL1 and Liver
 Skin Antibodies  >196 publications with CXCL1 and Skin
 Intestine Antibodies  >183 publications with CXCL1 and Intestine
 Heart Antibodies  >98 publications with CXCL1 and Heart
 Connective Tissue Antibodies  >74 publications with CXCL1 and Connective Tissue
 Uterus Antibodies  >33 publications with CXCL1 and Uterus
 Ascites Antibodies  >5 publications with CXCL1 and Ascites
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