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anti-CXCL2 antibody :: Goat CXCL2/MIP-2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS422140
Unit / Price
0.1 mg  /  $300 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CXCL2/MIP-2, Polyclonal Antibody

 Also Known As   

Goat anti-CXCL2/MIP-2 Antibody

 Product Synonym Names    CXCL2; chemokine (C-X-C motif) ligand 2; CINC-2a; GRO2; GROb; MGSA-b; MIP-2a; MIP2; MIP-2; MIP2A; SCYB2; GRO2 oncogene; MGSA beta; melanoma growth stimulatory activity beta; Macrophage Inflammatory Protein-2; CXCL2 antibody; chemokine (C-X-C motif) ligand 2 antibody; CINC-2a antibody; GRO2 antibody; GROb antibody; MGSA-b antibody; MIP-2a antibody; MIP2 antibody; MIP2A antibody; SCYB2 antibody; GRO2 oncogene antibody; MGSA beta antibody; melanoma growth stimulatory activity beta antibody; CXCL2 / MIP-2
 Product Gene Name   

anti-CXCL2 antibody

[Similar Products]
 Product Synonym Gene Name    MIP-2 [Similar Products]
 Antibody/Peptide Pairs    CXCL2 / MIP-2 peptide (MBS425276) is used for blocking the activity of CXCL2/MIP-2 antibody (MBS422140)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    KKIIEKMLKN GKSN
 OMIM    139110
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 Clonality    Polyclonal
 Host    Goat
 Species Reactivity    Tested: Human; Expected from sequence similarity: Human
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 Purity/Purification    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
 Form/Format    Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
 Concentration    100ug specific antibody in 200ul (lot specific)
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 Immunogen    Peptide with sequence C-KKIIEKMLKNGKSN, from the C Terminus of the protein sequence according to NP_002080.1.
 Epitope    C Terminus
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 Preparation and Storage    Aliquot and store at -20 degree C. Minimize freezing and thawing.
 ISO Certification    Manufactured in an ISO 9001:2015 Certified Laboratory.
 Other Notes    Small volumes of anti-CXCL2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CXCL2 antibody   

Peptide ELISA (EIA), Western Blot (WB)

 Application Notes for anti-CXCL2 antibody    Peptide ELISA: Antibody detection limit dilution 1: 32000.
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 Western Blot (WB) of anti-CXCL2 antibody    (0. 03ug/ml) staining of Daudi lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
anti-CXCL2 antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-CXCL2 antibody    (0.2ug/ml) staining of Human Duodenum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence
anti-CXCL2 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CXCL2. It may not necessarily be applicable to this product.
 NCBI GI #    4504155
 NCBI GeneID    2920
 NCBI Accession #    NP_002080.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_002089.3 [Other Products]
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 UniProt Secondary Accession #    Q6FGD6; Q9UPB8 [Other Products]
 UniProt Related Accession #    P19875 [Other Products]
 Molecular Weight    11,389 Da
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 NCBI Official Full Name    C-X-C motif chemokine 2
 NCBI Official Synonym Full Names    C-X-C motif chemokine ligand 2
 NCBI Official Symbol    CXCL2 [Similar Products]
 NCBI Official Synonym Symbols   
GRO2; GROb; MIP2; MIP2A; SCYB2; MGSA-b; MIP-2a; CINC-2a
[Similar Products]
 NCBI Protein Information    C-X-C motif chemokine 2
 UniProt Protein Name    C-X-C motif chemokine 2
 UniProt Synonym Protein Names   
Growth-regulated protein beta; Gro-beta
 Protein Family    C-X-C motif chemokine
 UniProt Gene Name    CXCL2 [Similar Products]
 UniProt Synonym Gene Names    GRO2; GROB; MIP2A; SCYB2; Gro-beta; MIP2-alpha; HSF [Similar Products]
 UniProt Entry Name    CXCL2_HUMAN
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 NCBI Summary for CXCL2    This antimicrobial gene is part of a chemokine superfamily that encodes secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CXC subfamily, is expressed at sites of inflammation and may suppress hematopoietic progenitor cell proliferation. [provided by RefSeq, Sep 2014]
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 UniProt Comments for CXCL2    CXCL2: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q21

Cellular Component: extracellular region

Molecular Function: CXCR chemokine receptor binding; protein binding

Biological Process: chemotaxis; G-protein coupled receptor protein signaling pathway; immune response; regulation of cell proliferation; response to lipopolysaccharide; response to molecule of bacterial origin
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 Research Articles on CXCL2    1. high GRO-beta expression correlates with poor prognosis and contributes to ovarian cancer tumorigenesis and metastasis.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CXCL2 antibodyPathways associated with anti-CXCL2 antibody
 Reference Product  PubMed Publications
 CXCR2 antibody  >188 publications with CXCL2 and CXCR2
 CCL5 antibody  >148 publications with CXCL2 and CCL5
 CXCL10 antibody  >133 publications with CXCL2 and CXCL10
 CCL20 antibody  >92 publications with CXCL2 and CCL20
 CXCL12 antibody  >64 publications with CXCL2 and CXCL12
 CCR2 antibody  >48 publications with CXCL2 and CCR2
 CXCR1 antibody  >31 publications with CXCL2 and CXCR1
 CXCL11 antibody  >24 publications with CXCL2 and CXCL11
 CCL19 antibody  >7 publications with CXCL2 and CCL19
 CXCL16 antibody  >6 publications with CXCL2 and CXCL16
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokines And Inflammatory Response Pathway antibodies  Cytokines And Inflammatory Response Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
Diseases associated with anti-CXCL2 antibodyOrgans/Tissues associated with anti-CXCL2 antibody
 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1147 publications with CXCL2 and Inflammation
 Necrosis Antibodies  >704 publications with CXCL2 and Necrosis
 Lung Diseases Antibodies  >429 publications with CXCL2 and Lung Diseases
 Lung Injury Antibodies  >288 publications with CXCL2 and Lung Injury
 Pneumonia Antibodies  >190 publications with CXCL2 and Pneumonia
 Reperfusion Injury Antibodies  >123 publications with CXCL2 and Reperfusion Injury
 Edema Antibodies  >108 publications with CXCL2 and Edema
 Wounds and Injuries Antibodies  >106 publications with CXCL2 and Wounds and Injuries
 Skin Diseases Antibodies  >97 publications with CXCL2 and Skin Diseases
 Liver Diseases Antibodies  >94 publications with CXCL2 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >1174 publications with CXCL2 and Blood
 Lung Antibodies  >695 publications with CXCL2 and Lung
 Liver Antibodies  >237 publications with CXCL2 and Liver
 Bone Antibodies  >192 publications with CXCL2 and Bone
 Bone Marrow Antibodies  >158 publications with CXCL2 and Bone Marrow
 Brain Antibodies  >140 publications with CXCL2 and Brain
 Intestine Antibodies  >127 publications with CXCL2 and Intestine
 Kidney Antibodies  >104 publications with CXCL2 and Kidney
 Eye Antibodies  >61 publications with CXCL2 and Eye
 Lymph Node Antibodies  >50 publications with CXCL2 and Lymph Node
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