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anti-CXCR6 antibody :: Rabbit anti-Human CXCR6 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS242091
Unit / Price
0.05 mg  /  $495 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CXCR6, Polyclonal Antibody

★Popular Item★
 Also Known As   

Rabbit Polyclonal to Human CXCR6

 Product Synonym Names    Anti-CXCR6 Antibody (N-Terminus) IHC-plus; CXCR6; CD186 antigen; CXCR-6; STRL33; TYMSTR; BONZO; CD186; CDw186; CXC-R6; Human CXCR6
 Product Gene Name   

anti-CXCR6 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605163
 3D Structure    ModBase 3D Structure for O00574
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    peptide corresponding to amino acids near the amino terminus of human Bonzo/STRL33 The sequence of this peptide differs from those of African green monkey and pig-tailed macaque by one or two amino acids, respectively,
 Purity/Purification    Immunoaffinity Purified
 Form/Format    PBS, 0.02% sodium azide.
 Concentration    1 mg/ml (lot specific)
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 Target Species    Human
 Immunogen Description    Synthetic peptide from human CXCR6.
 Immunogen Type    Synthetic peptide
 Immunogen    CXCR6 antibody was raised against synthetic peptide from human CXCR6.
 Antigen Modification    N-Terminus
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 Preparation and Storage    Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
 Other Notes    Small volumes of anti-CXCR6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Product Description specifically for anti-CXCR6 antibody

   Coreceptor usage of primary human immunodeficiency virus type 1 (HIV-1) isolates varies according to biological phenotype. The chemokine receptors CCR5 and CXCR4 are the major coreceptors that, together with CD4, govern HIV-1 entry into cells.
 Product Categories/Family for anti-CXCR6 antibody    Family: GPCR
Subfamily: Chemokine
 Applications Tested/Suitable for anti-CXCR6 antibody   

Immunohistochemistry (IHC - Paraffin), Western Blot (WB)

 Application Notes for anti-CXCR6 antibody    IHC-P (2.5 ug/ml), WB (1:500)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
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 Immunohistochemistry (IHC) of anti-CXCR6 antibody    Anti-CXCR6 antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
anti-CXCR6 antibody Immunohistochemistry (IHC) (IHC) image
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 Western Blot (WB) of anti-CXCR6 antibody    Western blot of Bonzo in human spleen tissue lysate in the absence (lane A) or presence (lane B) of peptide with Bonzo antibody at 1 ug/ml.
anti-CXCR6 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CXCR6. It may not necessarily be applicable to this product.
 NCBI GI #    5730106
 NCBI GeneID    10663
 NCBI Accession #    NP_006555.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006564.1 [Other Products]
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 UniProt Primary Accession #    O00574 [Other Products]
 UniProt Secondary Accession #    O00575; Q9HCA5 [Other Products]
 UniProt Related Accession #    O00574 [Other Products]
 Molecular Weight    39,280 Da
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 NCBI Official Full Name    C-X-C chemokine receptor type 6
 NCBI Official Synonym Full Names    chemokine (C-X-C motif) receptor 6
 NCBI Official Symbol    CXCR6 [Similar Products]
 NCBI Official Synonym Symbols   
BONZO; CD186; STRL33; TYMSTR
[Similar Products]
 NCBI Protein Information    C-X-C chemokine receptor type 6; CDw186; CXC-R6; CXCR-6; G protein-coupled receptor; G-protein coupled receptor bonzo; G-protein coupled receptor STRL33
 UniProt Protein Name    C-X-C chemokine receptor type 6
 UniProt Synonym Protein Names   
CDw186; G-protein coupled receptor STRL33; G-protein coupled receptor bonzo; CD_antigen: CD186
 Protein Family    C-X-C chemokine receptor
 UniProt Gene Name    CXCR6 [Similar Products]
 UniProt Synonym Gene Names    BONZO; STRL33; TYMSTR; CXC-R6; CXCR-6 [Similar Products]
 UniProt Entry Name    CXCR6_HUMAN
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 UniProt Comments for CXCR6    CXCR6: Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1

Chromosomal Location of Human Ortholog: 3p21

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; coreceptor activity; C-X-C chemokine receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; viral genome replication; inflammatory response; chemotaxis
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 Research Articles on CXCR6    1. CXCL16/CXCR6 interaction may play an important role in modifying the response of pDCs to environmental danger signals
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CXCR6 antibodyPathways associated with anti-CXCR6 antibody
 Reference Product  PubMed Publications
 CXCL16 antibody  >147 publications with CXCR6 and CXCL16
 CCR5 antibody  >84 publications with CXCR6 and CCR5
 CXCL10 antibody  >19 publications with CXCR6 and CXCL10
 CCL5 antibody  >17 publications with CXCR6 and CCL5
 CCL20 antibody  >12 publications with CXCR6 and CCL20
 CXCL9 antibody  >11 publications with CXCR6 and CXCL9
 CXCL13 antibody  >6 publications with CXCR6 and CXCL13
 CCL21 antibody  >2 publications with CXCR6 and CCL21
 CCL19 antibody  >2 publications with CXCR6 and CCL19
 CXCL11 antibody  >2 publications with CXCR6 and CXCL11
 Products by Pathway  Pathway Diagram
 Chemokine Receptors Bind Chemokines Pathway antibodies  Chemokine Receptors Bind Chemokines Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Chemokine Signaling Pathway antibodies  Chemokine Signaling Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
Diseases associated with anti-CXCR6 antibodyOrgans/Tissues associated with anti-CXCR6 antibody
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >17 publications with CXCR6 and Lung Diseases
 Nervous System Diseases Antibodies  >15 publications with CXCR6 and Nervous System Diseases
 Skin Diseases Antibodies  >10 publications with CXCR6 and Skin Diseases
 Brain Diseases Antibodies  >10 publications with CXCR6 and Brain Diseases
 Prostatic Neoplasms Antibodies  >9 publications with CXCR6 and Prostatic Neoplasms
 Liver Neoplasms Antibodies  >8 publications with CXCR6 and Liver Neoplasms
 Breast Neoplasms Antibodies  >8 publications with CXCR6 and Breast Neoplasms
 Neoplasms, Experimental Antibodies  >7 publications with CXCR6 and Neoplasms, Experimental
 Demyelinating Diseases Antibodies  >7 publications with CXCR6 and Demyelinating Diseases
 Lymphoma Antibodies  >7 publications with CXCR6 and Lymphoma
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >13 publications with CXCR6 and Brain
 Kidney Antibodies  >13 publications with CXCR6 and Kidney
 Spleen Antibodies  >12 publications with CXCR6 and Spleen
 Placenta Antibodies  >8 publications with CXCR6 and Placenta
 Uterus Antibodies  >2 publications with CXCR6 and Uterus
 Mammary Gland Antibodies  >1 publications with CXCR6 and Mammary Gland
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