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anti-CYB5R2 antibody :: Rabbit anti-Human, mouse CYB5R2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS7002261
Unit / Price
0.05 mg  /  $160 +1 FREE 8GB USB
0.1 mg  /  $235 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

CYB5R2, Polyclonal Antibody

★Popular Item★
 Also Known As   

CYB5R2 Antibody

 Product Synonym Names    NADH-cytochrome b5 reductase 2; b5R.2; CYB5R2
 Product Gene Name   

anti-CYB5R2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    608342
 3D Structure    ModBase 3D Structure for Q6BCY4
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, mouse
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 Purity/Purification    >95%,Protein G purified
 Form/Format    Liquid
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 Immunogen    Recombinant human NADH-cytochrome b5 reductase 2 protein
 Conjugation    Non-conjugated
 Storage Buffer    Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
 Santa Cruz Alternative    Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-161509 / sc-161510
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 Preparation and Storage    Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of anti-CYB5R2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CYB5R2 antibody

   NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST-1).
 Applications Tested/Suitable for anti-CYB5R2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

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 Western Blot (WB) of anti-CYB5R2 antibody    Western blot
All lanes: CYB5R2 antibody at 4ug/ml+Mouse kidney tissue
Goat polyclonal to rabbit at 1/10000 dilution
Predicted band size: 32,28 kDa
Observed band size: 31 kDa

anti-CYB5R2 antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CYB5R2 antibody    Immunohistochemistry of paraffin-embedded human testis tissue using MBS7002261 at dilution of 1:100
anti-CYB5R2 antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CYB5R2. It may not necessarily be applicable to this product.
 NCBI GI #    723586615
 NCBI GeneID    51700
 NCBI Accession #    NP_001289755.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001302826.1 [Other Products]
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 UniProt Primary Accession #    Q6BCY4 [Other Products]
 UniProt Secondary Accession #    Q9BVA3; Q9UF68; Q9UHJ0 [Other Products]
 UniProt Related Accession #    Q6BCY4 [Other Products]
 Molecular Weight    27,043 Da
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 NCBI Official Full Name    NADH-cytochrome b5 reductase 2 isoform 1
 NCBI Official Synonym Full Names    cytochrome b5 reductase 2
 NCBI Official Symbol    CYB5R2 [Similar Products]
 NCBI Official Synonym Symbols   
B5R.2
[Similar Products]
 NCBI Protein Information    NADH-cytochrome b5 reductase 2
 UniProt Protein Name    NADH-cytochrome b5 reductase 2
 Protein Family    NADH-cytochrome b5 reductase
 UniProt Gene Name    CYB5R2 [Similar Products]
 UniProt Synonym Gene Names    b5R.2 [Similar Products]
 UniProt Entry Name    NB5R2_HUMAN
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 NCBI Summary for CYB5R2    The protein encoded by this gene belongs to the flavoprotein pyridine nucleotide cytochrome reductase family of proteins. Cytochrome b-type NAD(P)H oxidoreductases are implicated in many processes including cholesterol biosynthesis, fatty acid desaturation and elongation, and respiratory burst in neutrophils and macrophages. Cytochrome b5 reductases have soluble and membrane-bound forms that are the product of alternative splicing. In animal cells, the membrane-bound form binds to the endoplasmic reticulum, where it is a member of a fatty acid desaturation complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
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 UniProt Comments for CYB5R2    CYB5R2: NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4- disulfophenyl]-2H tetrazolium monosodium salt (WST-1). Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.6.2.2; Oxidoreductase

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: membrane; mitochondrion; nucleus

Molecular Function: cytochrome-b5 reductase activity; protein binding

Biological Process: sterol biosynthetic process
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 Research Articles on CYB5R2    1. findings suggest that CYB5R2 may be a functional tumor suppressor gene, frequently inactivated by hypermethylation of its promoter in nasopharyngeal carcinoma
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CYB5R2 antibodyPathways associated with anti-CYB5R2 antibody
 Reference Product  PubMed Publications
 CYB5B antibody  >1 publications with CYB5R2 and CYB5B
 CYB5A antibody  >1 publications with CYB5R2 and CYB5A
 Products by Pathway  Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 Cytochrome P450 Pathway antibodies  Cytochrome P450 Pathway Diagram
Diseases associated with anti-CYB5R2 antibodyOrgans/Tissues associated with anti-CYB5R2 antibody
 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >1 publications with CYB5R2 and Congenital Abnormalities
 Abnormalities, Drug-Induced Antibodies  >1 publications with CYB5R2 and Abnormalities, Drug-Induced
 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >2 publications with CYB5R2 and Lymph Node
 Liver Antibodies  >2 publications with CYB5R2 and Liver
 Prostate Antibodies  >1 publications with CYB5R2 and Prostate
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