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anti-CDHE antibody :: Rabbit anti-Mouse Cadherin, Epithelial (CDHE) Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2005434 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $170 +1 FREE 8GB USB
0.1 mg  /  $210 +1 FREE 8GB USB
0.2 mg  /  $315 +1 FREE 8GB USB
1 mg  /  $745 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cadherin, Epithelial (CDHE), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Cadherin, Epithelial (CDHE)

 Product Gene Name   

anti-CDHE antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    The target protein is fused with a His-tag and its sequence is listed below.
MGHHHHHHSG SEF-RQKRDW VI PPISCPENEK GEFPKNLVQI KSNRDKETKV FYSITGQGAD KPPVGVFIIE RETGWLKVTQ PLDREAIAKY ILYSHAVSSN GEAVEDPMEI VITVTDQNDN RPEF
 3D Structure    ModBase 3D Structure for P09803
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Mouse
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 Specificity    The antibody is a rabbit polyclonal antibody raised against CDHE. It has been selected for its ability to recognize CDHE in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunogen    Recombinant CDHE (Arg153~Phe264) expressed in E.coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2035236
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-CDHE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CDHE antibody   

Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB)

 Application Notes for anti-CDHE antibody    Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
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 Western Blot (WB) of anti-CDHE antibody    (Figure. Western Blot; Sample: Recombinant protein.)
anti-CDHE antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CDHE antibody    (Used in DAB staining on formalin fixed paraffin-embedded Kidney tissue)
anti-CDHE antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CDHE. It may not necessarily be applicable to this product.
 NCBI GI #    6753374
 NCBI GeneID    12550
 NCBI Accession #    NP_033994.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_009864.3 [Other Products]
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 UniProt Primary Accession #    P09803 [Other Products]
 UniProt Secondary Accession #    Q61377 [Other Products]
 UniProt Related Accession #    P09803 [Other Products]
 Molecular Weight    98,256 Da
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 NCBI Official Full Name    cadherin-1 preproprotein
 NCBI Official Synonym Full Names    cadherin 1
 NCBI Official Symbol    Cdh1 [Similar Products]
 NCBI Official Synonym Symbols   
Um; UVO; Ecad; ARC-1; E-cad; L-CAM; AA960649
[Similar Products]
 NCBI Protein Information    cadherin-1
 UniProt Protein Name    Cadherin-1
 UniProt Synonym Protein Names   
ARC-1; Epithelial cadherin; E-cadherin
 Protein Family    Acetyl-CoA decarbonylase/synthase complex
 UniProt Gene Name    Cdh1 [Similar Products]
 UniProt Synonym Gene Names    E-cadherin [Similar Products]
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 NCBI Summary for CDHE    This gene encodes E-cadherin, a calcium-dependent cell adhesion molecule that functions in the establishment and maintenance of epithelial cell morphology during embryongenesis and adulthood. The encoded preproprotein undergoes proteolytic processing to generate a mature protein. Targeted mutations disrupting binding of calcium to the encoded protein in mice cause death in utero due to failed blastocyst and trophectoderm formation. This gene is located adjacent to a related cadherin gene on chromosome 8. [provided by RefSeq, Oct 2015]
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 UniProt Comments for CDHE    Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7 ().
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 Research Articles on CDHE    1. This study reveals a novel role for Cdh1 in craniofacial development through promoting APC-dependent non-proteolytic ubiquitination and activation of Gsc.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CDHE antibodyPathways associated with anti-CDHE antibody
 Reference Product  PubMed Publications
 Ctnnb1 antibody  >196 publications with CDHE and Ctnnb1
 Snai1 antibody  >34 publications with CDHE and Snai1
 Snai2 antibody  >24 publications with CDHE and Snai2
 Mmp7 antibody  >5 publications with CDHE and Mmp7
 Jup antibody  >5 publications with CDHE and Jup
 Cbll1 antibody  >2 publications with CDHE and Cbll1
 Klrg1 antibody  >1 publications with CDHE and Klrg1
 Ctnnd1 antibody  >1 publications with CDHE and Ctnnd1
 Products by Pathway  Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junction Pathway antibodies  Adherens Junction Pathway Diagram
 Adherens Junctions Interactions Pathway antibodies  Adherens Junctions Interactions Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cell Adhesion Proteins Pathway antibodies  Apoptotic Cleavage Of Cell Adhesion Proteins Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Bacterial Invasion Of Epithelial Cells Pathway antibodies  Bacterial Invasion Of Epithelial Cells Pathway Diagram
 Bladder Cancer Pathway antibodies  Bladder Cancer Pathway Diagram
Diseases associated with anti-CDHE antibodyOrgans/Tissues associated with anti-CDHE antibody
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >631 publications with CDHE and Carcinoma
 Stomach Neoplasms Antibodies  >360 publications with CDHE and Stomach Neoplasms
 Breast Neoplasms Antibodies  >306 publications with CDHE and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >219 publications with CDHE and Neoplasm Metastasis
 Neoplasm Invasiveness Antibodies  >201 publications with CDHE and Neoplasm Invasiveness
 Disease Progression Antibodies  >143 publications with CDHE and Disease Progression
 Colorectal Neoplasms Antibodies  >133 publications with CDHE and Colorectal Neoplasms
 Lung Neoplasms Antibodies  >98 publications with CDHE and Lung Neoplasms
 Carcinoma, Squamous Cell Antibodies  >91 publications with CDHE and Carcinoma, Squamous Cell
 Liver Neoplasms Antibodies  >80 publications with CDHE and Liver Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Stomach Antibodies  >378 publications with CDHE and Stomach
 Lung Antibodies  >136 publications with CDHE and Lung
 Liver Antibodies  >103 publications with CDHE and Liver
 Brain Antibodies  >73 publications with CDHE and Brain
 Prostate Antibodies  >69 publications with CDHE and Prostate
 Embryonic Tissue Antibodies  >53 publications with CDHE and Embryonic Tissue
 Kidney Antibodies  >52 publications with CDHE and Kidney
 Bladder Antibodies  >38 publications with CDHE and Bladder
 Skin Antibodies  >33 publications with CDHE and Skin
 Intestine Antibodies  >23 publications with CDHE and Intestine
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