NP_004920.1
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NCBI GenBank Nucleotide #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
calbindin
NCBI Official Synonym Full Names
calbindin 1, 28kDa
NCBI Official Synonym Symbols
NCBI Protein Information
calbindin; RTVL-H protein; calbindin 1, (28kD); calbindin D28; vitamin D-dependent calcium-binding protein, avian-type
UniProt Protein Name
Calbindin
UniProt Synonym Protein Names
Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-type
UniProt Synonym Gene Names
UniProt Entry Name
CALB1_HUMAN
NCBI Summary for CALB1
The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015]
UniProt Comments for CALB1
CALB1: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. Interacts with RANBP9. Belongs to the calbindin family.
Protein type: Calcium-binding
Chromosomal Location of Human Ortholog: 8q21.3
Cellular Component: cell soma; axon; dendrite; synapse; cytosol; nucleus
Molecular Function: vitamin D binding; protein binding; zinc ion binding; calcium ion binding
Biological Process: cytosolic calcium ion homeostasis; long-term memory; short-term memory; regulation of synaptic plasticity; locomotory behavior
Research Articles on CALB1
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Products associated with anti-CALB1 antibody
Pathways associated with anti-CALB1 antibody
Diseases associated with anti-CALB1 antibody
Organs/Tissues associated with anti-CALB1 antibody
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