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anti-CAMLG antibody :: Rabbit Calcium Modulating Ligand Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2032668 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $130 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $340 +1 FREE 8GB USB
1 mg  /  $800 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Calcium Modulating Ligand (CAMLG), Polyclonal Antibody

★Popular Item★
 Also Known As   

Calcium Modulating Ligand (CAMLG) Polyclonal Antibody

 Product Synonym Names    CAML; Calcium Signal-Modulating Cyclophilin Ligand; Calcium-Signal Modulating Cyclophilin Ligand; Cyclophilin B-Binding Protein
 Product Gene Name   

anti-CAMLG antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    U18242 mRNA
 3D Structure    ModBase 3D Structure for P49069
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human, Mouse, Rat
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 Specificity    The antibody is a rabbit polyclonal antibody raised against CAMLG. It has been selected for its ability to recognize CAMLG in immunohistochemical staining and western blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4 containing 0.02% NaN3, 50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Immunoglobulin Type    IgG
 Conjugate    No Conjugate
 Organism Species    Human
 Fragment    CAMLG (Gly19~Glu184)
 Quality Control    Content: The quality control contains recombinant CAMLG (Gly19~Glu184) disposed in loading buffer.
Usage: 10uL per well when 3,3'-Diaminobenzidine(DAB) as the substrate.
5uL per well when used in enhanced chemilumescent (ECL).
Note: The quality control is specifically manufactured as the positive control.Not used for other purposes.
Loading Buffer: 100mM Tris(pH8.8), 2% SDS, 200mM NaCl, 50% glycerol,BPB 0.01%, NaN3 0.02%.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2065082
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 Other Notes    Small volumes of anti-CAMLG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CAMLG antibody    Knock-Out Validation Antibody
 Applications Tested/Suitable for anti-CAMLG antibody   

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

 Application Notes for anti-CAMLG antibody    Western Blot: 1:50-400
Immunohistochemistry in formalin fixed frozen section: 1:50-500
Enzyme-linked Immunosorbent Assay: 1:100-200
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 Western Blot (WB) Knockout Verification of anti-CAMLG antibody    Knockout Verification: Lane 1: Wild-type Jurkat cell lysate; Lane 2: CAMLG knockout Jurkat cell lysate; Predicted MW: 33kd Observed MW: 37kd Primary Ab: 1ug/ml Rabbit Anti-Human CAMLG Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
anti-CAMLG antibody Western Blot (WB) Knockout Verification (WB) image
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 Western Blot (WB) of anti-CAMLG antibody    Western Blot; Sample: Human HepG2 cell lysate; Primary Ab: 1ug/ml Rabbit Anti-Human CAMLG Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
anti-CAMLG antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-CAMLG antibody    Western Blot; Sample: Recombinant protein.
anti-CAMLG antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CAMLG antibody    DAB staining on fromalin fixed paraffin- embedded Kidney tissue)
anti-CAMLG antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CAMLG. It may not necessarily be applicable to this product.
 NCBI GI #    4502559
 NCBI GeneID    819
 NCBI Accession #    NP_001736.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001745.3 [Other Products]
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 UniProt Primary Accession #    P49069 [Other Products]
 UniProt Secondary Accession #    A1L3Y3 [Other Products]
 UniProt Related Accession #    P49069 [Other Products]
 Molecular Weight    32,953 Da
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 NCBI Official Full Name    calcium signal-modulating cyclophilin ligand
 NCBI Official Synonym Full Names    calcium modulating ligand
 NCBI Official Symbol    CAMLG [Similar Products]
 NCBI Official Synonym Symbols   
CAML; GET2
[Similar Products]
 NCBI Protein Information    calcium signal-modulating cyclophilin ligand
 UniProt Protein Name    Calcium signal-modulating cyclophilin ligand
 Protein Family    Calcium signal-modulating cyclophilin ligand
 UniProt Gene Name    CAMLG [Similar Products]
 UniProt Synonym Gene Names    CAML; CAML [Similar Products]
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 NCBI Summary for CAMLG    The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CAMLG    CAMLG: Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B.

Protein type: Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: endoplasmic reticulum; integral component of membrane; membrane

Molecular Function: cell adhesion molecule binding; protein binding

Biological Process: defense response; epidermal growth factor receptor signaling pathway; receptor recycling; signal transduction; viral process
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 Research Articles on CAMLG    1. Found that the calcium-modulating cyclophilin ligand (CAMLG), which is involved in Ca(2+) signaling, was the major host cell PilA binding protein.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CAMLG antibodyDiseases associated with anti-CAMLG antibody
 Reference Product  PubMed Publications
 BST2 antibody  >3 publications with CAMLG and BST2
 TMUB1 antibody  >2 publications with CAMLG and TMUB1
 TNFRSF13B antibody  >2 publications with CAMLG and TNFRSF13B
 PKHD1 antibody  >1 publications with CAMLG and PKHD1
 EGFR antibody  >1 publications with CAMLG and EGFR
 PRLR antibody  >1 publications with CAMLG and PRLR
 RNF122 antibody  >1 publications with CAMLG and RNF122
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with CAMLG and Necrosis
 Carcinoma Antibodies  >1 publications with CAMLG and Carcinoma
 Kidney Diseases Antibodies  >1 publications with CAMLG and Kidney Diseases
Organs/Tissues associated with anti-CAMLG antibody
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >2 publications with CAMLG and Liver
 Bone Antibodies  >1 publications with CAMLG and Bone
 Thyroid Antibodies  >1 publications with CAMLG and Thyroid
 Vascular Antibodies  >1 publications with CAMLG and Vascular
 Prostate Antibodies  >1 publications with CAMLG and Prostate
 Kidney Antibodies  >1 publications with CAMLG and Kidney
 Thymus Antibodies  >1 publications with CAMLG and Thymus
 Uncharacterized Tissue Antibodies  >1 publications with CAMLG and Uncharacterized Tissue
 Brain Antibodies  >1 publications with CAMLG and Brain
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