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anti-CALU antibody :: Rabbit anti-Human Calumenin Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2026032 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $105 +1 FREE 8GB USB
0.02 mg  /  $125 +1 FREE 8GB USB
0.05 mg  /  $170 +1 FREE 8GB USB
0.1 mg  /  $220 +1 FREE 8GB USB
0.2 mg  /  $320 +1 FREE 8GB USB
1 mg  /  $760 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Calumenin, Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Calumenin (CALU)

 Product Gene Name   

anti-CALU antibody

[Similar Products]
 Matching Pairs    Antibody: Calumenin (MBS2026032)
Antigen: Calumenin (MBS2031508)
 Matching Pairs    Unconjugated Antibody: Calumenin (MBS2026032)
APC-CY7 Conjugated Antibody: Calumenin (CALU) (MBS2059872)
 Matching Pairs    Unconjugated Antibody: Calumenin (MBS2026032)
PE Conjugated Antibody: Calumenin (CALU) (MBS2059873)
 Matching Pairs    Unconjugated Antibody: Calumenin (MBS2026032)
APC-CY7 Conjugated Antibody: Calumenin (CALU) (MBS2059874)
 Matching Pairs    Unconjugated Antibody: Calumenin (MBS2026032)
Cy3 Conjugated Antibody: Calumenin (CALU) (MBS2059875)
 Matching Pairs    Unconjugated Antibody: Calumenin (MBS2026032)
FITC Conjugated Antibody: Calumenin (CALU) (MBS2059876)
 Matching Pairs    Unconjugated Antibody: Calumenin (MBS2026032)
HRP Conjugated Antibody: Calumenin (CALU) (MBS2059877)
 Matching Pairs    Unconjugated Antibody: Calumenin (MBS2026032)
APC-CY7 Conjugated Secondary Antibody: Immunoglobulin G (MBS2090675)
 Matching Pairs    Unconjugated Antibody: Calumenin (MBS2026032)
Unconjugated Secondary Antibody: Immunoglobulin G (MBS2090678)
 Matching Pairs    Unconjugated Antibody: Calumenin (MBS2026032)
Biotin Conjugated Antibody: Calumenin (CALU) (MBS2093856)
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Immunogen Sequence    Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below.
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- K PTEKKDRVHH EPQLSDKVHN DAQSFDYDHD AFLGAEEAKT FDQLTPEESK ERLGKIVSKI DGDKDGFVTV DELKDWIKFA QKRWIYEDVE RQWKGHDLNE DGLVSWEEYK NATYGYVLDD PDPDDGFNYK QMMVRDERRF KMADKDGDLI ATKEEFTAFL HPEEYDYMKD IVVQETMEDI DKNADGFIDL EEYIGDMYSH DGNTDEPEWV KTEREQFVEF RDKNRDGKMD KEETKDWILP SDYDHAEAEA RHLVYESDQN KDGKLTKEEI VDKYDLFVGS QATDFGEALV RHDEF
 OMIM    U67280 mRNA
 3D Structure    ModBase 3D Structure for O43852
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against CALU. It has beenselected for its ability to recognize CALU in immunohistochemical staining andwestern blotting.
 Purity/Purification    Affinity Chromatography
 Form/Format    Liquid
 Concentration    200ug/ml (lot specific)
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 Fragment    CALU (Lys20~Phe315)
 Organism Species    Homo sapiens (Human)
 Conjugate    No Conjugate
 Immunogen    Recombinant CALU (Lys20~Phe315) expressed in E Coli.
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2059874
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 Preparation and Storage    Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
 ISO Certification    Manufactured in an ISO 9001:2015 and ISO 13485:2016 Certified Laboratory.
 Supply Chain Verification    Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available. Please inquire.
 Other Notes    Small volumes of anti-CALU antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Product Categories/Family for anti-CALU antibody    Knock-Out Validation Antibody
 Applications Tested/Suitable for anti-CALU antibody   

Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA)

 Application Notes for anti-CALU antibody    Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user.
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 Western Blot (WB) Knockout Verification of anti-CALU antibody    Knockout Verification: Lane 1: Wild-type Jurkat cell lysate; Lane 2: CALU knockout Jurkat cell lysate; Predicted MW: 37kd Observed MW: 37kd Primary Ab: 3ug/ml Rabbit Anti-Human CALU Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
anti-CALU antibody Western Blot (WB) Knockout Verification (WB) image
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 Western Blot (WB) of anti-CALU antibody    Western Blot; Sample: Lane1: Human HepG2 Cells; Lane2: Human Jurkat Cells; Lane3: Mouse Kidney Tissue.
anti-CALU antibody Western Blot (WB) (WB) image
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 Western Blot (WB) of anti-CALU antibody    Western Blot; Sample: Recombinant CALU, Human.
anti-CALU antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CALU antibody    DAB staining on IHC-P; Samples: Human Kidney Tissue.
anti-CALU antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CALU antibody    DAB staining on IHC-P; Samples: Human Stomach Cancer Tissue
anti-CALU antibody Immunohistochemistry (IHC) (IHC) image
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 Immunohistochemistry (IHC) of anti-CALU antibody    DAB staining on IHC-P; Samples: Human Breast Cancer Tissue
anti-CALU antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CALU. It may not necessarily be applicable to this product.
 NCBI GI #    194578885
 NCBI GeneID    813
 NCBI Accession #    NP_001124146.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001130674.2 [Other Products]
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 UniProt Primary Accession #    O43852 [Other Products]
 UniProt Secondary Accession #    B3KPG9; D6QS48; D6QS49; D6QS50; D6QS51; D6QS52; D6QS53; D6QS54; D6QS55; D6QS56; D6QS57 [Other Products]
 UniProt Related Accession #    O43852 [Other Products]
 Molecular Weight    19,455 Da
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 NCBI Official Full Name    calumenin isoform b
 NCBI Official Synonym Full Names    calumenin
 NCBI Official Symbol    CALU [Similar Products]
 NCBI Protein Information    calumenin
 UniProt Protein Name    Calumenin
 UniProt Synonym Protein Names   
Crocalbin; IEF SSP 9302
 Protein Family    Calumenin
 UniProt Gene Name    CALU [Similar Products]
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 NCBI Summary for CALU    The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008]
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 UniProt Comments for CALU    CALU: Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity. Belongs to the CREC family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Calcium-binding; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q32.1

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; endoplasmic reticulum membrane; extracellular region; Golgi apparatus; melanosome; membrane; sarcoplasmic reticulum lumen

Molecular Function: calcium ion binding; protein binding

Biological Process: cellular protein metabolic process; post-translational protein modification
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 Research Articles on CALU    1. The Calumenin modulates Sarco/Endoplasmic reticulumCa2+ATPase (SERCA) pump activity without drastically affecting ER-Ca(2+) concentration.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CALU antibodyPathways associated with anti-CALU antibody
 Reference Product  PubMed Publications
 CFTR antibody  >141 publications with CALU and CFTR
 VKORC1 antibody  >22 publications with CALU and VKORC1
 GGCX antibody  >14 publications with CALU and GGCX
 ATP2A2 antibody  >3 publications with CALU and ATP2A2
 RYR2 antibody  >2 publications with CALU and RYR2
 Products by Pathway  Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Platelet Degranulation Pathway antibodies  Platelet Degranulation Pathway Diagram
 Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies  Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram
Diseases associated with anti-CALU antibodyOrgans/Tissues associated with anti-CALU antibody
 Disease Name  Pubmed Publications
 Lung Diseases Antibodies  >320 publications with CALU and Lung Diseases
 Lung Neoplasms Antibodies  >278 publications with CALU and Lung Neoplasms
 Fibrosis Antibodies  >181 publications with CALU and Fibrosis
 Inflammation Antibodies  >58 publications with CALU and Inflammation
 Breast Neoplasms Antibodies  >48 publications with CALU and Breast Neoplasms
 Disease Models, Animal Antibodies  >41 publications with CALU and Disease Models, Animal
 Necrosis Antibodies  >24 publications with CALU and Necrosis
 Nervous System Diseases Antibodies  >11 publications with CALU and Nervous System Diseases
 Liver Neoplasms Antibodies  >11 publications with CALU and Liver Neoplasms
 Liver Diseases Antibodies  >10 publications with CALU and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >635 publications with CALU and Lung
 Blood Antibodies  >110 publications with CALU and Blood
 Vascular Antibodies  >49 publications with CALU and Vascular
 Kidney Antibodies  >41 publications with CALU and Kidney
 Trachea Antibodies  >34 publications with CALU and Trachea
 Brain Antibodies  >32 publications with CALU and Brain
 Liver Antibodies  >30 publications with CALU and Liver
 Muscle Antibodies  >22 publications with CALU and Muscle
 Intestine Antibodies  >21 publications with CALU and Intestine
 Prostate Antibodies  >19 publications with CALU and Prostate
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