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anti-CNR2 antibody :: Rabbit Cannabinoid receptor 2 Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS851908
Unit / Price
0.1 mg  /  $330 +1 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Cannabinoid receptor 2 (CNR2), Polyclonal Antibody

 Also Known As   

Cannabinoid receptor 2 Antibody

 Product Gene Name   

anti-CNR2 antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    605051
 3D Structure    ModBase 3D Structure for P34972
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 Clonality    Polyclonal
 Host    Rabbit
 Species Reactivity    Human
Predicted: Mouse, Rat
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 Form/Format    Purified by protein A column containing 0.02% NaN3
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 Preparation and Storage    Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
 Other Notes    Small volumes of anti-CNR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for anti-CNR2 antibody

   Rabbit polyclonal Cannabinoid receptor 2 (1) antibody was raised against a recombinate human Cannabinoid receptor 2 protein 1-360aa (NM_001841).
 Product Categories/Family for anti-CNR2 antibody    Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
 Applications Tested/Suitable for anti-CNR2 antibody   

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

 Application Notes for anti-CNR2 antibody    ELISA: 1:20,000-1:80,000
WB: 1:200-1:1,000
IHC: 1:50-200
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 Testing Data of anti-CNR2 antibody    anti-CNR2 antibody Testing Data image
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 Testing Data of anti-CNR2 antibody    anti-CNR2 antibody Testing Data image
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NCBI/Uniprot data below describe general gene information for CNR2. It may not necessarily be applicable to this product.
 NCBI GI #    4502929
 NCBI GeneID    1269
 NCBI Accession #    NP_001832.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001841.2 [Other Products]
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 UniProt Primary Accession #    P34972 [Other Products]
 UniProt Secondary Accession #    Q4VBK8; Q5JRH7; Q6B0G7; Q6NSY0; C6ES44 [Other Products]
 UniProt Related Accession #    P34972 [Other Products]
 Molecular Weight    39,681 Da [Similar Products]
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 NCBI Official Full Name    cannabinoid receptor 2
 NCBI Official Synonym Full Names    cannabinoid receptor 2
 NCBI Official Symbol    CNR2 [Similar Products]
 NCBI Official Synonym Symbols   
CB2; CX5; CB-2
[Similar Products]
 NCBI Protein Information    cannabinoid receptor 2
 UniProt Protein Name    Cannabinoid receptor 2
 UniProt Synonym Protein Names   
CX5
 Protein Family    Cannabinoid receptor
 UniProt Gene Name    CNR2 [Similar Products]
 UniProt Synonym Gene Names    CB2A; CB2B; CB-2; CB2; hCB2 [Similar Products]
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 NCBI Summary for CNR2    The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors. [provided by RefSeq, Jul 2008]
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 UniProt Comments for CNR2    Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis.
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Product References and Citations for anti-CNR2 antibody

   (1) Ishiguro, H., Carpio, O., Horiuchi, Y., et al; .A nonsynonymous polymorphism in cannabinoid CB2 receptor gene is associated with eating disorders in humans and food intake is modified in mice by its ligands.Synapse 64 (1), 92-96 (2010).
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 Research Articles on CNR2    1. CB2 activation with sub-micromolar doses of agonists, which could be more similar to endogenous levels of cannabinoids, promote colon cancer progression in a process that involves AKT and GSK3beta.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CNR2 antibodyPathways associated with anti-CNR2 antibody
 Reference Product  PubMed Publications
 FAAH antibody  >16 publications with CNR2 and FAAH
 Products by Pathway  Pathway Diagram
 Class A/1 (Rhodopsin-like Receptors) Pathway antibodies  Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
 Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway antibodies  Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 G Alpha (i) Signalling Events Pathway antibodies  G Alpha (i) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 GPCR Ligand Binding Pathway antibodies  GPCR Ligand Binding Pathway Diagram
 GPCRs, Class A Rhodopsin-like Pathway antibodies  GPCRs, Class A Rhodopsin-like Pathway Diagram
 Metabolic Disorders Of Biological Oxidation Enzymes Pathway antibodies  Metabolic Disorders Of Biological Oxidation Enzymes Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
 Neuroactive Ligand-receptor Interaction Pathway antibodies  Neuroactive Ligand-receptor Interaction Pathway Diagram
Diseases associated with anti-CNR2 antibodyOrgans/Tissues associated with anti-CNR2 antibody
 Disease Name  Pubmed Publications
 Pain Antibodies  >47 publications with CNR2 and Pain
 Inflammation Antibodies  >41 publications with CNR2 and Inflammation
 Disease Models, Animal Antibodies  >35 publications with CNR2 and Disease Models, Animal
 Hyperalgesia Antibodies  >17 publications with CNR2 and Hyperalgesia
 Immune System Diseases Antibodies  >16 publications with CNR2 and Immune System Diseases
 Necrosis Antibodies  >14 publications with CNR2 and Necrosis
 Heart Diseases Antibodies  >12 publications with CNR2 and Heart Diseases
 Edema Antibodies  >10 publications with CNR2 and Edema
 Fibrosis Antibodies  >7 publications with CNR2 and Fibrosis
 Fatty Liver Antibodies  >4 publications with CNR2 and Fatty Liver
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >37 publications with CNR2 and Blood
 Liver Antibodies  >18 publications with CNR2 and Liver
 Bone Marrow Antibodies  >5 publications with CNR2 and Bone Marrow
 Placenta Antibodies  >2 publications with CNR2 and Placenta
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