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anti-CRAT antibody :: Rabbit anti-Human Carnitine Acetyltransferase Polyclonal Antibody

Scan QR to view Datasheet Catalog #    MBS2026731 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
0.01 mg  /  $110 +1 FREE 8GB USB
0.02 mg  /  $130 +1 FREE 8GB USB
0.05 mg  /  $175 +1 FREE 8GB USB
0.1 mg  /  $225 +1 FREE 8GB USB
0.2 mg  /  $340 +1 FREE 8GB USB
1 mg  /  $800 +1 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Carnitine Acetyltransferase (CRAT), Polyclonal Antibody

★Popular Item★
 Also Known As   

Polyclonal Antibody to Carnitine Acetyltransferase (CRAT)

 Product Gene Name   

anti-CRAT antibody

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 OMIM    BT006801 mRNA
 3D Structure    ModBase 3D Structure for P43155
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 Clonality    Polyclonal
 Isotype    IgG
 Host    Rabbit
 Species Reactivity    Human
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 Specificity    The antibody is a rabbit polyclonal antibody raised against CRAT. It has beenselected for its ability to recognize CRAT in immunohistochemical staining andwestern blotting.
 Purity/Purification    Antigen-specific Affinity Chromatography
 Form/Format    Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
 Concentration    200ug/ml (lot specific)
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 Source    Polyclonal antibody preparation
 Traits    Liquid
 Immunogen    Recombinant CRAT (Lys363~Leu626) expressed in E.coli
 Conjugated Antibody    The APC conjugated antibody version of this item is also available as catalog #MBS2065358
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 Preparation and Storage    Storage: Avoid repeated freeze/thaw cycles.
Store at 4 degree C for frequent use.
Aliquot and store at -20 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.
 Other Notes    Small volumes of anti-CRAT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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 Applications Tested/Suitable for anti-CRAT antibody   


 Application Notes for anti-CRAT antibody    Western blotting: 0.5-2ug/ml
Immunocytochemistry in formalin fixed cells: 5-20ug/ml
Immunohistochemistry in formalin fixed frozen section: 5-20ug/ml
Immunohistochemistry in paraffin section: 5-20ug/ml
Enzyme-linked Immunosorbent Assay: 0.05-2ug/ml
Optimal working dilutions must be determined by end user
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 Western Blot (WB) of anti-CRAT antibody    (Figure. Western Blot; Sample: Recombinant CRAT, Human.)
anti-CRAT antibody Western Blot (WB) (WB) image
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 Immunohistochemistry (IHC) of anti-CRAT antibody    (Used in DAB staining on formalin fixed paraffin-embedded testis tissue)
anti-CRAT antibody Immunohistochemistry (IHC) (IHC) image
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NCBI/Uniprot data below describe general gene information for CRAT. It may not necessarily be applicable to this product.
 NCBI GI #    530390532
 NCBI GeneID    1384
 NCBI Accession #    XP_005251765.1 [Other Products]
 NCBI GenBank Nucleotide #    XM_005251708.3 [Other Products]
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 UniProt Primary Accession #    P43155 [Other Products]
 UniProt Secondary Accession #    Q5T952; Q9BW16 [Other Products]
 UniProt Related Accession #    P43155 [Other Products]
 Molecular Weight    61,870 Da
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 NCBI Official Full Name    carnitine O-acetyltransferase isoform X3
 NCBI Official Synonym Full Names    carnitine O-acetyltransferase
 NCBI Official Symbol    CRAT [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    carnitine O-acetyltransferase
 UniProt Protein Name    Carnitine O-acetyltransferase
 UniProt Synonym Protein Names   
Carnitine acetyltransferase; CAT; CrAT
 Protein Family    Carnitine O-acetyltransferase
 UniProt Gene Name    CRAT [Similar Products]
 UniProt Synonym Gene Names    CAT1; Carnitine acetylase; CAT; CrAT [Similar Products]
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 NCBI Summary for CRAT    This gene encodes carnitine O-acetyltransferase, a member of the carnitine acyltransferase family and a key metabolic pathway enzyme which plays an important role in energy homeostasis and fat metabolism. This enzyme catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acyl-CoA/CoA. It is found in both the mitochondria and the peroxisome. Alternative splicing results in transcript variants encoding different isoforms that may localize to different subcellular compartments. [provided by RefSeq, Oct 2016]
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 UniProt Comments for CRAT    CRAT: Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria. Belongs to the carnitine/choline acetyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Acetyltransferase; EC; Mitochondrial

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: endoplasmic reticulum; mitochondrial inner membrane; mitochondrion; peroxisomal matrix; peroxisome

Molecular Function: carnitine O-acetyltransferase activity; receptor binding

Biological Process: carnitine metabolic process, CoA-linked; fatty acid beta-oxidation using acyl-CoA oxidase; transport
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 Research Articles on CRAT    1. We provide evidence that the downregulation of hsa-miR-124-3p, hsa-miR-129-5p and hsa-miR-378 induced an increase in both expression and activity of CPT1A, CACT and CrAT in malignant prostate cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with anti-CRAT antibodyPathways associated with anti-CRAT antibody
 Reference Product  PubMed Publications
 CPT2 antibody  >10 publications with CRAT and CPT2
 CPT1A antibody  >9 publications with CRAT and CPT1A
 CPT1B antibody  >5 publications with CRAT and CPT1B
 CPT1C antibody  >2 publications with CRAT and CPT1C
 SLC25A20 antibody  >2 publications with CRAT and SLC25A20
 Products by Pathway  Pathway Diagram
 Beta-oxidation Of Pristanoyl-CoA Pathway antibodies  Beta-oxidation Of Pristanoyl-CoA Pathway Diagram
 Beta-oxidation Of Very Long Chain Fatty Acids Pathway antibodies  Beta-oxidation Of Very Long Chain Fatty Acids Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Peroxisomal Lipid Metabolism Pathway antibodies  Peroxisomal Lipid Metabolism Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Peroxisome Pathway antibodies  Peroxisome Pathway Diagram
 Mitochondrial L-carnitine Shuttle Pathway antibodies  Mitochondrial L-carnitine Shuttle Pathway Diagram
 Mitochondrial L-carnitine Shuttle Pathway antibodies  Mitochondrial L-carnitine Shuttle Pathway Diagram
Diseases associated with anti-CRAT antibodyOrgans/Tissues associated with anti-CRAT antibody
 Disease Name  Pubmed Publications
 Kidney Diseases Antibodies  >22 publications with CRAT and Kidney Diseases
 Renal Insufficiency Antibodies  >18 publications with CRAT and Renal Insufficiency
 Cardiovascular Diseases Antibodies  >9 publications with CRAT and Cardiovascular Diseases
 Inflammation Antibodies  >9 publications with CRAT and Inflammation
 Abnormalities, Drug-Induced Antibodies  >6 publications with CRAT and Abnormalities, Drug-Induced
 Heart Diseases Antibodies  >6 publications with CRAT and Heart Diseases
 Insulin Resistance Antibodies  >5 publications with CRAT and Insulin Resistance
 Fatty Liver Antibodies  >4 publications with CRAT and Fatty Liver
 Drug-Related Side Effects and Adverse Reactions Antibodies  >3 publications with CRAT and Drug-Related Side Effects and Adverse Reactions
 Mitochondrial Diseases Antibodies  >3 publications with CRAT and Mitochondrial Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >40 publications with CRAT and Blood
 Kidney Antibodies  >24 publications with CRAT and Kidney
 Bone Antibodies  >18 publications with CRAT and Bone
 Muscle Antibodies  >17 publications with CRAT and Muscle
 Heart Antibodies  >12 publications with CRAT and Heart
 Liver Antibodies  >10 publications with CRAT and Liver
 Lung Antibodies  >6 publications with CRAT and Lung
 Connective Tissue Antibodies  >5 publications with CRAT and Connective Tissue
 Brain Antibodies  >5 publications with CRAT and Brain
 Prostate Antibodies  >3 publications with CRAT and Prostate
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